Cortisone

A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)

Also Known As:

Networked: 5496 relevant articles (103 outcomes, 286 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Walker, Brian R: 12 articles (02/2015 - 02/2002)
2.	Andrew, Ruth: 10 articles (02/2015 - 07/2002)
3.	Stewart, P M: 8 articles (04/2015 - 11/2000)
4.	Stewart, Paul M: 7 articles (12/2010 - 01/2002)
5.	Fardella, Carlos E: 6 articles (01/2016 - 01/2005)
6.	Carvajal, Cristian A: 5 articles (01/2016 - 01/2005)
7.	Tomlinson, Jeremy W: 5 articles (12/2010 - 01/2002)
8.	Walker, B R: 5 articles (10/2004 - 11/2000)
9.	Jonas, J B: 5 articles (09/2001 - 09/2000)
10.	Campino, Carmen: 4 articles (01/2016 - 01/2005)

Related Diseases

1.	Rheumatoid Arthritis 12/01/2005 - "Following the announcement in 1949 in the USA that cortisone offered rheumatoid arthritis sufferers effective treatment for their crippling disease, the Ministry of Health came under considerable pressure from the medical profession and the public to make cortisone available in Britain. " 06/01/2002 - "Fifty years of experience with cortisone therapy in the study and treatment of rheumatoid arthritis." 07/01/1984 - "Of the 15 patients investigated, 6 (40%) developed during the period of study severe forms of rheumatoid arthritis (RA) which required the introduction of continuous cortisone therapy. " 06/01/1959 - "Trials of cortisone analogues in the treatment of rheumatoid arthritis." 01/01/1958 - "Cortisone in long-term treatment of rheumatoid arthritis: a three year study."
2.	Pain (Aches) 01/01/2012 - "Autologous blood injection improved pain and function in a worker's compensation cohort of patients with chronic lateral epicondylitis, who had not had relief with cortisone injection." 11/01/1977 - "In selected cases immediate relief from pain occurs after administration of cortisone or a suitable cortisone-derivative. " 05/01/2014 - "I recently received a cortisone injection in my knee, and it substantially reduced the pain and stiffness. " 12/01/2013 - "Disability and pain after cortisone versus placebo injection for trapeziometacarpal arthrosis and de Quervain syndrome." 03/01/2012 - "Arthroscopic arthrolysis of the knee joint and intensive active and passive physical treatment, in combination with a cortisone regime, temporarily increased the ROM and reduced pain. "
3.	Addison Disease (Addison's Disease) 05/21/2012 - "The patient was diagnosed with Addison's disease and responded well to treatment with cortisone. " 02/25/1961 - "[An improvement in the treatment of Addison's disease: the cortisone-fluorohydrocortisone combination]." 01/01/1990 - "No evidence of nerve cell loss was found in three cases of Addison's disease that had received cortisone treatment, which is consistent with the experimental observation that even very low levels of cortisone in adrenalectomized rats are sufficient to prevent granule cell loss." 01/01/1981 - "In primary Addison's disease, very high levels (654-1 413 pg/ml) before cortisone therapy and their decline to nearly normal values during therapy are described. " 04/01/1980 - "The patient was on cortisone therapy for Addison's disease prior to the pregnancy. "
4.	Dermatomyositis (Dermatopolymyositis) 07/01/1953 - "[Anatomoclinical and metabolic modifications in a case of dermatomyositis apparently cured by cortisone]." 06/01/1955 - "[Clinical aspects and cortisone therapy of dermatomyositis]." 04/01/1954 - "[Successful cortisone therapy of dermatomyositis]." 01/01/1954 - "[Subacute dermatomyositis and necrotic capillaritis with rapid fatal evolution; failure of cortisone]." 03/01/1953 - "[Fatal acute dermatomyositis; failure of cortisone therapy]."
5.	Waterhouse-Friderichsen Syndrome 05/01/1953 - "[A case of Waterhouse-Friderichsen syndrome cured with cortisone]." 05/01/1965 - "[WATERHOUSE-FRIDERICHSEN SYNDROME--CORTISONE THERAPY OR NOT?]." 06/07/1952 - "Waterhouse-Friderichsen syndrome treated with cortisone; report of two cases." 07/28/1951 - "Waterhouse-Friderichsen syndrome; report of cure effected with cortisone." 07/28/1951 - "Nature of Waterhouse-Friderichsen syndrome; report of case with successful treatment with cortisone."

Related Drugs and Biologics

1.	Adrenocorticotropic Hormone (ACTH)
2.	Hydrocortisone (Cortisol)
3.	Anti-Bacterial Agents (Antibiotics)
4.	Steroids
5.	Prednisolone (Predate)
6.	Adrenal Cortex Hormones (Corticosteroids)
7.	Cyclophosphamide (Cytoxan)
8.	Histamine (Histamine Dihydrochloride)
9.	Isoniazid (Ftivazide)
10.	Griseofulvin (Grifulvin V)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Splenectomy
3.	Intra-Articular Injections
4.	Hypophysectomy
5.	Tenotomy