Contractile Proteins

Proteins which participate in contractile processes. They include MUSCLE PROTEINS as well as those found in other cells and tissues. In the latter, these proteins participate in localized contractile events in the cytoplasm, in motile activity, and in cell aggregation phenomena.

Also Known As:

Networked: 345 relevant articles (1 outcomes, 32 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Sawicki, Grzegorz: 6 articles (06/2014 - 05/2003)
2.	Cadete, Virgilio J J: 4 articles (01/2014 - 05/2011)
3.	Sawicka, Jolanta: 4 articles (01/2014 - 05/2003)
4.	Debold, Edward P: 3 articles (01/2015 - 08/2012)
5.	Pearce, William J: 3 articles (10/2014 - 01/2011)
6.	Williams, James M: 3 articles (10/2014 - 01/2011)
7.	Lin, Han-Bin: 3 articles (06/2014 - 03/2013)
8.	Lin, Zhiqiang: 2 articles (11/2015 - 07/2015)
9.	Kataoka, Masaharu: 2 articles (11/2015 - 07/2015)
10.	Hu, Xiaoyun: 2 articles (11/2015 - 07/2015)

Related Diseases

1.	Hypertrophy 07/01/2002 - "The weight of evidence regarding mechanical unloading using assist devices suggests that hemodynamic restoration is accompanied by regression of cellular hypertrophy, normalization of the neuroendocrine axis, improved expression of contractile proteins, enhanced cellular respiratory control, and decreases in markers of apoptosis and cellular stress. " 07/01/1994 - "Using an adult mouse aortic-banded model of pressure-overload hypertrophy and isolated cardiomyocyte mechanics studies, we examined the hypothesis that contractile depression is due to altered cardiac contractile proteins rather than changes in left ventricular (LV) geometry, loading, or the extracellular matrix. " 07/01/1990 - "STUDY OBJECTIVE - The aim was to examine the contractile state, the inotropic response to [Ca2+]e and the Ca2+ sensitivity of the contractile proteins in different models of hypertensive hypertrophy in an early stage of evolution (3-4 weeks). " 12/01/1984 - "These studies demonstrate that physiologic and pathologic hypertrophy in the rat have distinctly opposite effects on contractile proteins and contractile performance. " 11/01/2011 - "Remarkably, myocardial hypertrophy was only evident 48 h post-ablation and was associated with increased heart weight and altered expression of contractile proteins. "
2.	Heart Failure 12/01/2013 - "Recent evidence suggests that the measurement of even minute amounts of circulating cardiac contractile proteins may be useful in the clinical assessment of patients with heart failure. " 10/01/2009 - "Recent evidence suggests that measurement of the release of cardiac contractile proteins into the bloodstream at lower levels may be useful in the clinical assessment of patients who have acute or chronic heart failure. " 06/01/2009 - "MiR-208 is involved in the shift toward a fetal gene expression pattern in contractile proteins in heart failure. " 06/01/2008 - "End-stage heart failure is characterized by a number of abnormalities at the cellular level, which include changes in excitation-contraction coupling, alterations in contractile proteins and activation/deactivation of signaling pathways. " 04/28/2007 - "[Modification of contractile proteins in heart failure]."
3.	Anoxia (Hypoxia) 06/01/1993 - "The results of this study suggest that taken individually neither the effect of a rise in [Pi] nor a fall in pH on Ca(2+)-activated force generated by the contractile proteins can account for the effect of hypoxia on spontaneous contractions." 08/01/2010 - "Signaling pathways activated by hypoxia modify cytoskeletal and contractile proteins and alter the biomechanical properties of endothelial cells. " 11/01/2002 - "Effects of long-term hypoxia and development on cardiac contractile proteins in fetal and adult sheep." 05/01/1993 - "This increased tolerance of cardiomyopathic hearts to hypoxia may be related to alterations in myocardial contractile proteins and/or energy utilization, or substrate availability." 08/01/1990 - "[Changes in the Ca2+ sensitivity of the contractile proteins in the smooth muscle cells of the rat portal vein during stretching and hypoxia]."
4.	Muscular Diseases (Myopathy) 12/01/2004 - "Multi-minicore disease (MmD) is an infrequent congenital myopathy, defined by structural changes in optic and electron microscopy, namely, multiple small areas lacking oxidative enzyme activity and focal disorganization of contractile proteins involving at most a few sarcomeres. " 04/01/2004 - "During overreaching and overtraining, a myopathy-like state is observed in skeletal muscle with depressed turnover of contractile proteins (e.g. " 07/01/1994 - "Turnover of skeletal muscle contractile proteins in glucocorticoid myopathy." 03/01/1988 - "It seems that the glucocorticoid-caused myopathy is a result of elevated degradation of contractile proteins. " 01/01/1980 - "Changes in the contractile proteins of skeletal muscles induced by steroid myopathy."
5.	Hypertrophic Cardiomyopathy (Asymmetric Septal Hypertrophy) 08/01/2000 - "The properties of mutant contractile proteins that cause hypertrophic cardiomyopathy (HCM) have been investigated in expression studies and in mouse models. " 01/01/2002 - "Hypertrophic cardiomyopathy is caused by mutations in genes, which code for sarcomeric contractile proteins. " 01/01/2002 - "Hypertrophic obstructive cardiomyopathy has been proposed to be the result of gene mutations of contractile proteins. " 03/01/2001 - "Hypertrophic cardiomyopathy (HCM) is a genetic disease of the sarcomeric contractile proteins. " 05/01/2000 - "Hypertrophic cardiomyopathy (HCM) is an inherited disorder of cardiac muscle that has been linked to mutations in the contractile proteins that make up the cardiac muscle sarcomere. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Protein Isoforms (Isoforms)
3.	Myosin-Light-Chain Kinase
4.	Desmin
5.	Myosins (Myosin)
6.	Calcium
7.	Enzymes
8.	Troponin I
9.	Collagen
10.	Antibodies

Related Therapies and Procedures

1.	Denervation
2.	Microelectrodes
3.	Induced Heart Arrest (Cardioplegia)