Complement C8 (C8 Complement)
A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9.
Also Known As:
C8 Complement; Complement 8; Complement Component 8; Complement Component C8 alpha; Complement Component C8 alpha Chain; Complement Component C8 beta; Complement Component C8 beta Chain; Complement Component C8 gamma; Complement Component C8 gamma Chain; C8, Complement; Complement, C8; Component 8, Complement
Networked: 15
relevant articles (0 outcomes,
3 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Coolen, Jordy P M:
1 article
(11/2021)
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2. | Henriet, Stefanie S V:
1 article
(11/2021)
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3. | Langereis, Jeroen D:
1 article
(11/2021)
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4. | de Groot, Ronald:
1 article
(11/2021)
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5. | de Jonge, Marien I:
1 article
(11/2021)
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6. | van den Broek, Bryan:
1 article
(11/2021)
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7. | van der Flier, Michiel:
1 article
(11/2021)
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8. | Afridi, Ruqayya:
1 article
(01/2021)
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9. | Choe, Youngshik:
1 article
(01/2021)
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10. | Han, Jin:
1 article
(01/2021)
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