Chromium

A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002,1985), chromium and some of its compounds have been listed as known carcinogens.

Networked: 2733 relevant articles (119 outcomes, 511 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Thyssen, Jacob P: 20 articles (11/2021 - 02/2010)
2.	Johansen, Jeanne D: 19 articles (11/2021 - 03/2011)
3.	Vincent, John B: 17 articles (03/2021 - 01/2004)
4.	Stone, Gregg W: 15 articles (01/2022 - 04/2008)
5.	Menné, Torkil: 14 articles (11/2021 - 09/2002)
6.	Zachariae, Claus: 11 articles (11/2021 - 11/2013)
7.	Bagchi, Debasis: 11 articles (01/2021 - 01/2002)
8.	Mao, Frank Chiahung: 10 articles (04/2020 - 04/2009)
9.	Serruys, Patrick W: 9 articles (01/2022 - 10/2013)
10.	Costa, Max: 9 articles (01/2020 - 06/2007)

Related Diseases

1.	Insulin Resistance 12/01/2023 - "Chromium (Cr) results in a range of effects when fed to ruminants, but most studies have shown improved insulin sensitivity. " 02/01/2017 - "Chromium (Cr) has been reported to improve insulin sensitivity in pigs. " 04/01/2015 - "Treatment with chromium has been shown to improve insulin sensitivity in adults with PCOS. " 11/01/2011 - "Chromium supplementation produces modest improvement in insulin sensitivity in adults. " 03/01/2010 - "In summary, chromium improved insulin resistance, metabolic abnormalities, and body composition in HIV+ patients. "
2.	Type 2 Diabetes Mellitus (MODY) 11/01/1998 - "In a study performed in China, the use of 1000 micrograms of chromium per day (five times above the upper limit of the estimated safe and adequate daily dietary intake) was highly effective in relieving many of the symptomatic manifestations of type 2 diabetes mellitus, including a return of the HbA1C levels into the normal range. " 07/01/2018 - "As one of chromium supplements, the purpose of this study is to examine the efficacy of high chromium yeast on the type 2 diabetes and drying method on its bioactivity, which will be useful for research and development of high-chromium yeast and improvement of pharmacological activity-based quality control." 11/01/2015 - "Significant reduction in chromium levels are probable indicators of metabolic response to oxidative stress in patients with type 2 diabetes mellitus. " 03/01/2006 - "There is no evidence that high-dose chromium treatment is effective in obese Western patients with type 2 diabetes." 12/01/1994 - "Ours is the first report of a significant reduction in serum TGs in a group of NIDDM patients treated with chromium. "
3.	Weight Gain 07/01/2001 - "3. Results showed that 1 mg/kg chromium supplementation significantly improved weight gain and food intake at 9 to 18 weeks of age but did not significantly influence performance at 19 to 22 week of age. " 06/01/2009 - "A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to prevent weight gain on smoking cessation." 01/01/2017 - "Supplementation of chromium and nano-chromium improved performance including weight gain and feed conversion ratio of heat-stressed chickens. " 06/01/2009 - "Insufficient people stopped smoking to properly test the efficacy of chromium in preventing weight gain, but the point estimate indicates a potentially worthwhile benefit." 01/01/2002 - "Chromium had no effect on weight gain, but 20 mg/kg supplemental Cr resulted in 18.57% reduction in feed consumption and improved feed efficiency by 16.77%. "
4.	Body Weight (Weight, Body) 12/01/1995 - "However, the chromium group failed to show a significantly greater reduction in either percent body fat or body weight, or a greater increase in lean body mass, than did the placebo group. " 04/01/2010 - "Chromium supplemented diet had lower body weight loss and improved dry matter intake with consequent reduction in the energy balance deficits during the first period after calving when compared with the control group. " 10/01/2002 - "Increased supplemental chromium resulted in an increase in body weight (p = 0.01, linear), feed intake (p < or = 0.05, linear), and carcass characteristics (p < or = 0.05, linear) and improved feed efficiency (p = 0.01, linear). " 06/01/2002 - "Increased supplemental chromium increased body weight (P = 0.05, linear), feed intake (P = 0.05, linear), egg production (P = 0.01, linear) and also improved feed efficiency (P = 0.01, linear). " 11/07/2023 - "To achieve this, PubMed, Scopus, Embase, Cochrane Library, and Web of Science were searched for randomized clinical trials (RCTs) that reported the effects of chromium supplementation on body composition such as body weight (BW), body mass index (BMI), fat mass (FM), and waist circumference (WC) in patients with T2DM from inception until July 2023. "
5.	Coronary Artery Disease (Coronary Atherosclerosis) 10/01/1984 - "Recent measurements have demonstrated that plasma chromium levels in patients with coronary artery disease are very much lower than in normal subjects. " 04/01/1978 - "The group with coronary artery disease had significantly lower serum chromium concentrations than did the group with normally patent arteries." 04/01/1978 - "Only subjects free of coronary artery disease had chromium concentrations greater than or equal to 5.50 microgram/liter. " 04/01/1978 - "Serum chromium and angiographically determined coronary artery disease." 12/01/2009 - "Chromium status and glucose tolerance in Saudi men with and without coronary artery disease."

Related Drugs and Biologics

1.	Cobalt
2.	Glucose (Dextrose)
3.	Zinc
4.	Erbium
5.	Insulin (Novolin)
6.	Edetic Acid (EDTA)
7.	Lipids
8.	Everolimus
9.	Scandium
10.	Gallium

Related Therapies and Procedures

1.	Stents
2.	Solid-State Lasers
3.	Glycemic Control
4.	Therapeutics
5.	Lasers (Laser)