Chlorohydrins

Any of the compounds derived from a group of glycols or polyhydroxy alcohols by chlorine substitution for part of the hydroxyl groups. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)

Also Known As:

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Casas, Josefina: 1 article (05/2013)
2.	Closa, Daniel: 1 article (05/2013)
3.	Fabriàs, Gemma: 1 article (05/2013)
4.	Franco-Pons, Neus: 1 article (05/2013)
5.	Gea-Sorlí, Sabrina: 1 article (05/2013)
6.	Gelpí, Emilio: 1 article (05/2013)
7.	de-Madaria, Enrique: 1 article (05/2013)
8.	Dever, Gary: 1 article (01/2005)
9.	Spickett, Corinne M: 1 article (01/2005)

Related Diseases

1.	Atherosclerosis 01/01/2005 - "There is some evidence that chlorohydrins have biological effects that may be relevant to atherosclerosis, but further work is needed to elucidate their pro-inflammatory properties, and to understand the mechanisms and balance of biological effects that could result from oxidation of complex mixtures of lipids in a pathophysiological situation."
2.	Pancreatitis 05/01/2013 - "Administration of 250-μM lipid chlorohydrins, which is the concentration found in ascitic fluid, induces the expression of TNFα and interleukin-1β in peritoneal macrophages and increases the systemic inflammatory response in pancreatitis. " 05/01/2013 - "Induced acute pancreatitis results in a substantial release not only of free fatty acids but also of the chlorohydrins of both oleic and linoleic acids from adipose tissue. "
3.	Inflammation (Inflammations) 05/01/2013 - "Chlorohydrins were also instilled in the rats' peritoneal cavity, and their effects on peritoneal macrophages activation and in systemic inflammation were evaluated. "
4.	Hemolysis 10/01/1997 - "Modification of red cell membrane lipids by hypochlorous acid and haemolysis by preformed lipid chlorohydrins."
5.	Carcinoma (Carcinomatosis) 08/01/1996 - "When intact red cells, neutrophils, and MCF7 mammary carcinoma cells were exposed to HOCl, cholesterol chlorohydrins were formed, as detected by TLC. "

Related Drugs and Biologics

1.	Lipids
2.	Complex Mixtures
3.	Membrane Lipids
4.	Linoleic Acids
5.	Hypochlorous Acid (Hypochlorite)
6.	Nonesterified Fatty Acids (NEFA)
7.	Cholesterol