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Cheilitis

Inflammation of the lips. It is of various etiologies and degrees of pathology.
Also Known As:
Cheilitides
Networked: 340 relevant articles (24 outcomes, 14 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Acne Vulgaris
2. Headache (Headaches)
3. Neoplasms (Cancer)
4. Alopecia (Baldness)
5. Actinic Keratosis

Experts

1. Katoh, Norito: 3 articles (06/2020 - 10/2003)
2. Goossens, An: 3 articles (11/2018 - 03/2016)
3. Metin, Nurcan: 2 articles (10/2022 - 07/2016)
4. Jacob, Sharon E: 2 articles (12/2020 - 07/2011)
5. Foti, Caterina: 2 articles (08/2020 - 07/2014)
6. Romita, Paolo: 2 articles (08/2020 - 07/2014)
7. de Groot, Anton: 2 articles (08/2020 - 01/2017)
8. Budimir, Jozo: 2 articles (06/2020 - 01/2012)
9. Lugović-Mihić, Liborija: 2 articles (06/2020 - 06/2018)
10. Hagvall, Lina: 2 articles (08/2019 - 03/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cheilitis:
1. Isotretinoin (Accutane)FDA LinkGeneric
2. Tacrolimus (Prograf)FDA LinkGeneric
3. Trichloroacetic AcidIBA
4. Oxygen (Dioxygen)IBA
5. RetinoidsIBA
6. Adrenal Cortex Hormones (Corticosteroids)IBA
7. EtretinateFDA Link
8. Immunoglobulin E (IgE)IBA
05/01/1989 - "In a group of 535 children and 103 adult patients with atopic dermatitis no differences were observed between persons with normal and raised IgE level with respect to incidence of lesions in the first or the first three months of life, the total number of the positive RAST results and the most intense reactions, that is 4 degrees, the percent of helper and suppressor T-cells, duration of remission, darkening of lower eyelids, cheilitis, involvement of the hands, the feet, the elbow flexures or knee flexures. "
02/01/1991 - "A positive history in both parents and/or their families was associated with higher IgE titres, earlier appearance of skin changes, more frequent occurrence of urticaria, allergic respiratory diseases, cheilitis, and, in women, nipple eczema. "
01/01/2022 - "Special IgE level to FX5 and the degree of food-specific IgG to wheat were seen higher in exfoliative cheilitis patients than in healthy control (P < 0.05). "
01/01/2022 - "Laboratory tests included serum total IgE, allergen-specific IgE, and food-specific IgG. Increased serum total IgE level, positive food-specific IgG were seen more frequently in exfoliative cheilitis patients than in healthy control (P < 0.05). "
07/01/2011 - "Out of 20 examined minor criteria, most common was cutaneous infection in 168(80.0%) patients followed by coursed influenced by environmental factor in 140(66.7%), high IgE level in 126(60.0%), intolerance of wool in 105(50.0%), xerosis in 92(43.8%), infra-orbital fold in 83(39.5%), ichthyosis in 72(34.3%), early age of onset in 65(31.0%), itch on sweating in 56(26.7%), palmary hyperlinearity in 52(24.8%), food hypersensitivity in 40(19.0%), keratosis pilaris in 31(14.8%), pityriasis alba in 30(14.3%), facial erythema in 25(1.9%), cheilitis in 22(10.5%), hand eczema in 19(9.0%), foot eczema in 16(7.6%), intolerance of lipid solvent in 14(6.7% ), scalp scaling in 11(5.2%) and infra-auricular fissure in 10(4.8%). "
9. Voriconazole (Vfend)FDA LinkGeneric
10. Calcineurin InhibitorsIBA

Therapies and Procedures

1. Therapeutics
2. Lasers (Laser)
06/01/2015 - "Excimer laser therapy is a well-tolerated and effective treatment for refractory exfoliative cheilitis with twice weekly laser treatments of up to 700 mJ/cm2. "
12/01/2009 - "These include - among others - de-novo growth of hair outside the area treated by laser, potentiation of co-existing vellus hair in the treatment area, induction or aggravation of acne, rosacea-like rash, premature grayness of hair, tunneling of hair under the skin, prolonged diffuse redness and edema of the face, focal hypopigmentation of the lip, angular cheilitis, allergic reaction to the cooling gas, and inflammatory and pigmentary changes of pre-existing nevi. "
01/01/2022 - "Es wurden Empfehlungen verabschiedet zu nicht-vermehrt melanozytenhaltigen Hautveränderungen (Epheliden, postinflammatorische Hyperpigmentierungen einschließlich Berloque-Dermatitis, seborrhoische Keratosen, Schmutz- und Schmucktätowierungen sowie Metallablagerungen), Hypopigmentierungen (Vitiligo), benignen nichtpigmentierten Neoplasien (fibröse Nasenpapel, Naevus sebaceus, epidermaler Naevus, Neurofibrome, seboglanduläre Hyperplasien, Syringome, Xanthelasmata palpebrarum), entzündlichen Dermatosen (Akne papulopustulosa/conglobata, Akne inversa, Granuloma faciale, Lichen sclerosus, Lupus erythematodes, Psoriasis vulgaris, Rosazea und Rhinophym), Falten/Dermatochalasis/Striae, Hypertrichose, Narben (atroph, hypertroph; Keloide, Verbrennungs- und Verbrühungsnarben), laser-assisted skin healing, Onychomykosen, Präkanzerosen und malignen Tumoren (aktinische Keratosen/Feldkanzerisierung, Cheilitis actinica, Basalzellkarzinom), vaskulären Hautveränderungen (Angiokeratom, Angiom, Hämangiom, Malformation, Besenreiser, Granuloma teleangiekaticum (pyogenicum), Rubeosis (Erythrosis interfollicularis colli, Ulerythema ophryogenes), Naevus flammeus, Teleangiektasien und Morbus Osler (Hereditäre Hämorrhagische Teleangiektasie) sowie viralen Hautveränderungen (Condylomata acuminata, Mollusca contagiosa, Verrucae planae juveniles, Verrucae vulgares und Verrucae palmares et plantares)."
01/01/2022 - "Further recommendations focus on the treatment of skin lesions without an increased amount of melanocytes (ephelides, postinflammatory hyperpigmentation including berloque dermatitis, seborrheic keratoses, traumatic/decorative tattoos and metallic deposits), hypopigmentation (vitiligo), benign non-pigmented neoplasms (fibrous papule of the nose, nevus sebaceus, epidermal nevus, neurofibroma, sebaceous gland hyperplasia, syringoma, xanthelasma palpebrarum), inflammatory dermatoses (acne papulopustulosa/conglobata, acne inversa, granuloma faciale, lichen sclerosus, lupus erythematosus, psoriasis vulgaris, rosacea, rhinophyma), wrinkles/dermatochalasis/striae, hypertrichosis, scars (atrophic, hypertrophic; keloids, burn/scald scars), laser-assisted skin healing, onychomycosis, precancerous lesions and malignant tumors (actinic keratoses/field cancerization, cheilitis actinica, basal cell carcinoma), vascular skin lesions (angiokeratoma, angioma, hemangioma, malformation, spider veins, granuloma telangiectaticum (pyogenic granuloma), rubeosis (erythrosis interfollicularis colli, ulerythema ophryogenes), nevus flammeus, telangiectasias and Osler's disease (hereditary hemorrhagic telangiectasia) and viral skin lesions (condylomata acuminata, mollusca contagiosa, verrucae planae juveniles/vulgares/ verrucae palmares et plantares)."
01/01/2017 - "A newly developed solution in wound care in the form of a SG has proven to be a highly effective treatment for a series of 4 clinically challenging cases presented in this article: postprocedure healing after a laser treatment, nonhealing scalp wounds, chronic relapsing xerotic eczematous cheilitis, and the treatment of scars caused by third degree burns. "
3. Drug Therapy (Chemotherapy)
4. Excimer Lasers
5. Laser Therapy (Surgery, Laser)