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Charcoal (Charbon)

An amorphous form of carbon prepared from the incomplete combustion of animal or vegetable matter, e.g., wood. The activated form of charcoal is used in the treatment of poisoning. (Grant & Hackh's Chemical Dictionary, 5th ed)

Also Known As:

Charbon; Activated Charcoal; Actidose; Actidose-Aqua; Adsorba; Cambridge Laboratories Brand of Activated Charcoal; Carbomix; Central Brand of Activated Charcoal; CharcoAid; CharcoCaps; Charcodote; Chefaro Brand of Activated Charcoal; Cheplapharm Brand of Activated Charcoal; Formocarbine; Gambro Brand of Activated Charcoal; GlaxoSmithKline Brand of Activated Charcoal; Hevert Brand of Activated Charcoal; Insta-Char; Kerr Brand of Activated Charcoal; Kohle-Compretten; Kohle-Hevert; Kohle-Pulvis; Kohle-Tabletten Boxo-Pharm; Köhler Brand of Activated Charcoal; Liqui-Char; Little Remedies Brand of Activated Charcoal; Merck Brand of Activated Charcoal; Merck Selbstmedikation Brand of Activated Charcoal; Monarch Brand of Activated Charcoal; Norit; Paddock Brand 1 of Activated Charcoal; Paddock Brand 2 of Activated Charcoal; Penn Brand of Activated Charcoal; Pharmascience Brand of Activated Charcoal; Pharmygiène Brand of Activated Charcoal; Requa Brand of Activated Charcoal; Ultracarbon; Charcoal, Activated

Networked: 1495 relevant articles (105 outcomes, 110 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Elements
  - Carbon: 4704
    - Charcoal: 1495

Experts

1.	Manoguerra, Anthony S: 7 articles (01/2008 - 07/2002)
2.	Chyka, Peter A: 7 articles (01/2008 - 08/2003)
3.	Chen, Ying-Yeh: 6 articles (02/2015 - 11/2009)
4.	Yip, Paul S F: 6 articles (04/2014 - 01/2007)
5.	Eddleston, Michael: 6 articles (05/2013 - 09/2003)
6.	Erdman, Andrew R: 6 articles (01/2008 - 01/2006)
7.	Booze, Lisa L: 6 articles (01/2008 - 01/2006)
8.	Nelson, Lewis S: 6 articles (01/2008 - 01/2006)
9.	Woolf, Alan D: 6 articles (01/2008 - 01/2006)
10.	Caravati, E Martin: 6 articles (01/2008 - 01/2006)

Related Diseases

1.	Poisoning 01/01/2010 - "Oral activated charcoal (oAC) is a safe and well tolerated treatment for acute poisoning, more recently shown to have significant immunomodulatory effects in man. " 05/01/2009 - "Administration of repeated doses of charcoal (1-2 g/h every 2-4 hours) may be effective in case of oleander poisoning. " 09/01/2007 - "Charcoal HP was an effective treatment for severe FAM poisoning. " 01/01/2007 - "Although activated charcoal is widely used for the treatment of self-poisoning, its effectiveness is unknown. " 12/01/2003 - "Activated charcoal is useful in the management of poisonings, but it is not harmless. "
2.	Renal Insufficiency (Renal Failure) 07/01/1988 - "Consequently, the increase in both drugs transported into the intestinal lumen induced by renal failure may enhance the intestinal clearance of the drug by oral administration of activated charcoal." 02/01/1990 - "The apparent changes in the pharmacokinetic parameters induced by charcoal administration were more marked in rabbits with renal failure than in normal rabbits; however, induction of renal failure did not augment the charcoal-induced clearance of gentamicin quantitatively." 10/01/2009 - "The efficacy of an enterosorbent based on low-esterified pectin, activated charcoal, and polyphepan was evaluated in rats with experimental renal failure. " 06/01/1978 - "Charcoal, in divided oral doses totalling 35 g/day, was administered to six patients with renal insufficiency (creatinine clearance of 0 to 45 ml/min). " 03/01/1990 - "If so, treatment of renal failure rats with activated charcoal should partly reverse the increased CNS sensitivity to phenobarbital and to other drugs similarly affected. "
3.	Overdose 01/01/2014 - "This study shows that acute overdoses with thiopurines have a favourable outcome in the majority of cases and provides preliminary evidence that gastrointestinal decontamination with activated charcoal may reduce symptom development after overdose of these substances if patients present to medical services soon after ingestion." 07/01/2010 - "There are clinical trials, research and position statements that have examined the effectiveness of activated charcoal in a number of overdoses of different medications, but there is still a debate surrounding the evidence based practice of administering activated charcoal in patients who have taken a drug overdose due to lack of evidence. " 01/01/2004 - "Additional study is required to determine whether in patients with anticholinergic drug overdose, activated charcoal is effective at times beyond the recommendation for overdoses of drugs without this pharmacodynamic effect." 01/01/1987 - "These findings support previous in vitro and human volunteer studies advocating the rapid administration of activated charcoal in acute tricyclic antidepressant overdoses." 09/01/2010 - "In addition, the charcoal cookie was rated as more palatable than the aqueous charcoal suspension, suggesting that the charcoal cookie could be an attractive alternative to the charcoal slurry for managing drug overdoses."
4.	Acute Liver Failure (Fulminant Hepatic Failure) 01/01/1985 - "Charcoal haemoperfusion also reduced the incidence of cerebral oedema which is a major cause of death in fulminant hepatic failure. " 09/25/1982 - "Earlier charcoal haemoperfusion in fulminant hepatic failure." 01/01/1982 - "The increased platelet adhesiveness might predispose to the formation of platelet aggregates in the blood observed during charcoal haemoperfusion in patients with fulminant hepatic failure." 01/01/1980 - "The effects of 8-hour haemoperfusion through an activated charcoal column on fulminant hepatic failure were assessed in 10 dogs. " 01/01/1980 - "Haemoperfusion through activated charcoal in dogs with fulminant liver failure."
5.	Breast Neoplasms (Breast Cancer) 08/01/2007 - "A well-tolerated, low-diffusion charcoal suspension has been designed to tattoo breast tumors. " 02/01/1995 - "Pre-operative localization of non-palpable lesions in breast cancer by charcoal suspension." 01/01/1992 - "Control of proliferation of MCF-7 breast cancer cells in a commercial preparation of charcoal-stripped adult bovine serum." 08/01/2007 - "In a series of 109 patients with large breast tumors, a 4% or 10% charcoal suspension was injected at the time of the initial biopsy before preoperative chemotherapy. " 10/01/2006 - "In a separate experiment using rats bearing breast cancer (Walker 256-TC), TJ-14, Neo/Bac, and charcoal at the same dose regimen improved CPT-11-induced intestinal toxicity without reducing CPT-11's antitumor activity. "

Related Drugs and Biologics

1.	Acetaminophen (Paracetamol)
2.	Acetylcysteine (Siran)
3.	Theophylline (Theon)
4.	Charcoal (Charbon)
5.	Phenobarbital (Luminal)
6.	Castor Oil (Oil, Castor)
7.	Digoxin (Digitek)
8.	Atropine (Hyoscyamine)
9.	Cholestyramine Resin (Questran)
10.	Coffee

Related Therapies and Procedures

1.	Hemoperfusion
2.	Oral Administration
3.	Renal Dialysis (Hemodialysis)
4.	Drug Therapy (Chemotherapy)
5.	Tattooing