Chancre

09/01/2015 - "The typical finding in primary syphilis stage is a unique, painless chancre with indurated borders. "
08/01/2015 - "Extragenital chancres occur in at least 5% of patients with primary syphilis, and the oral mucosa is the most frequent location as a consequence of orogenital/oroanal contact with an infectious lesion. "
08/01/2015 - "Primary syphilis of the oropharynx: an unusual location of a chancre."
04/01/2015 - "Tonsillar chancre as unusual manifestation of primary syphilis."
01/01/2012 - "Two (9.5%) of primary syphilis showed multiple chancre. "

03/27/2013 - "Secondary syphilis with persisting hard chancre on the forearm."
02/01/2013 - "Three cases of primary syphilitic chancre and one case of secondary syphilis were included. "
01/01/2012 - "Concomitant primary chancre and lesions of secondary syphilis were seen in 2 (20%) patients. "
09/29/2008 - "Two case stories are presented; one case illustrates how a patient with classical symptoms of secondary syphilis was overlooked by doctors of several specialities for one year, and the other case is of a patient with a lesion on the penis presenting clinically, serologically and histologically as a syphilitic chancre, but it proved to be a rare chronic inflammatory condition known as a pseudotumor. "
04/01/2007 - "pallidum in swabs of chancres and primary and secondary syphilis mucocutaneous lesions. "

12/01/1980 - "Thus a uniform and standard penicillin dosage allowing no safety margin may help in the superficial healing of a syphilitic chancre or the resolution of a roseola but it will certainly be insufficient to kill Treponema pallidum. "
07/01/1963 - "[PROBLEM OF TREATMENT OF A SYPHILITIC CHANCRE IN A NEPHRITIC PATIENT HYPERALLERGIC TO PENICILLIN]."
01/01/1955 - "[Penicillin-resistant syphilitic chancre]."
08/01/1951 - "Local herxheimer reaction following application of penicillin solution to syphilitic chancres."
08/03/1946 - "Delayed Syphilitic Chancre after Penicillin."

03/01/2006 - "Chancre redux or reinfection? "
07/01/1978 - "Monorecidive or chancre redux."
12/01/1964 - "CHANCRE REDUX."
09/01/1964 - "PSEUDO-CHANCRE REDUX WITH NEGATIVE SEROLOGY. "
12/01/1961 - "[A case of chancre redux caused by indiscriminate use of antibiotic medication]."

12/01/1994 - "By cannulating the afferent and efferent lymphatic ducts draining the skin and regional lymph node, the progressive development and migration of trypanosomes from the chancre was monitored and the expression of metacyclic antigen types (M-VATs) was determined. "
09/01/1990 - "Chancre formation would thus appear to be vital for the induction of comprehensive immune recognition of the metacyclic variable antigen repertoire deposited in the skin by infected tsetse, and hence development of protective immunity."
06/01/1987 - "It is suggested that the reduced immune response to metacyclic variable antigen types could be a result of the absence of cellular infiltration, i.e., chancre development in the skin at the tsetse bite site. "
03/01/1986 - "By 7.5 weeks of infection, syphilitic rabbit sera recognized 10 of 13 antigens; the most evident increase in serological reactivity was directed against a polypeptide of Mr 45,000, suggesting that the development of a strong serological response against this polypeptide correlated with the onset of chancre immunity."
12/01/2014 - "Healing of the primary chancre occurs as antibodies against outer membrane antigens facilitate opsonophagocytosis of the bacteria by activated macrophages. "

10/01/2005 - "After injection of penicillin G benzathine for 3 weeks, the rectal chancre and the palpable mass disappeared."
02/01/1987 - "Chancres in untreated animals were dark-field positive throughout the 16-day observation period; all benzathine penicillin-treated rabbits were dark-field negative 1 day after the initiation of therapy. "
01/01/2013 - "A 51-year-old male presented with bilateral nongranulomatous anterior uveitis associated with an isolated syphilitic chancre of the tongue that was successfully treated with parenteral benzathine penicillin. "
01/01/1990 - "Following production of primary chancres by intradermal inoculation of 10(6) Treponema pallidum, groups of six rabbits were treated with benzathine penicillin (200,000 units im weekly for two weeks), erythromycin base (30 mg/kg/day orally four times daily for 15 days) or azithromycin (30 mg/kg/day given orally once or twice daily for 15 days); one group was untreated. "

09/01/2007 - "Despite achieving high titers (>1:50,000) of serum antibodies, none of the rabbits displayed chancre immunity after intradermal challenge with viable T. "
05/01/1948 - "pallidum derived from rabbit testicular chancres regularly caused the appearance of Wassermann and flocculation antibodies in significantly increased titer. "
12/01/2014 - "Healing of the primary chancre occurs as antibodies against outer membrane antigens facilitate opsonophagocytosis of the bacteria by activated macrophages. "
06/01/2008 - "Subsequent examination of the original tissue sample by polymerase chain reaction, immunohistochemistry using Treponema pallidum-specific antibodies, and silver staining revealed large numbers of syphilis bacteria, confirming the diagnosis of extragenital chancre."

11/01/1990 - "Mononuclear cell subpopulations in local skin reactions (chancres) in sheep infected with metacyclic forms of Trypanosoma congolense were studied by indirect immunoperoxidase staining using a panel of monoclonal antibodies (MoAbs) specific for ovine leucocyte subsets. "
03/01/1990 - "Expression of nine metacyclic variable antigen types (M-VATs) of Trypanosoma congolense in chancres from infected rabbits was determined using monoclonal antibodies raised against metacyclic forms of trypanosomes. "
09/01/1990 - "Most of the trypanosomes recovered from the chancre tissue fluid were found to bear the same variable surface glycoprotein (VSG) epitopes as the corresponding metacyclics for as long as 13 days p.i., as revealed by indirect immunofluorescence using mouse anti-metacyclic VSG hyperimmune sera and monoclonal antibodies. "

03/01/1990 - "In infected sheep neutralizing antibodies against M-VATs were detected by day 14 in lymph from efferent lymphatics draining lymph nodes in the region of chancres. "
10/01/1982 - "Although animals subjected to the second challenge by tsetse flies showed no appreciable increase in parasitemia and, in most instances, no chancre reaction at the site where the tsetse bit, they developed readily detectable neutralizing antibody to the metacyclic trypanosomes. "

07/01/1953 - "[The effects of streptomycin on the course of soft chancre]."
12/01/1951 - "[Local streptomycin therapy of soft chancre; preliminary communication]."

05/01/2000 - "Syphilitic chancre despite use of condoms: "condom chancre"."
05/01/1974 - " He had intercourse with an unknown lady without using the condoms supplied by the vasectomy camp 4 days after a vasectomy; 15 days later the chancres appeared. "
11/01/2009 - " 279 syphilis cases with informative baseline clinical and serologic data, HIV infection was significantly associated with men having sex with men, French origin, multiple partners, lesser usage of condom, history of sexually transmitted disease, early syphilis, anal primary chancre, and cutaneous eruption. "

02/01/1992 - "Primary tuberculous chancre in a renal transplant patient."
10/01/1981 - "A 38-year-old, renal transplant patient developed painful, extensive, chancre-like genital ulcerations. "

01/01/1981 - "Rabbits that had been infected intravenously did not develop disseminated lesions or orchitis after treatment, and chancres produced by intradermal infection regressed and healed rapidly after the initiation of therapy. "
03/01/2006 - "An HIV-positive heterosexual man presented with a recurrent penile chancre, 20 months after treatment with intramuscular procaine benzyl penicillin. "

07/01/1953 - "[Lesions of the oral cavity due to prostheses; clinical and histological data on the relationship between oral chancre and prosthesis]."

05/01/1974 - " He had intercourse with an unknown lady without using the condoms supplied by the vasectomy camp 4 days after a vasectomy; 15 days later the chancres appeared. "
05/01/1974 - " The author knows of no other cases where chancres developed on the vasectomy wounds. "
05/01/1974 - "This is the case report of a 40-year-old Hindu male who developed bilateral and symmetrical primary chancres on his vasectomy wounds. "
05/01/1974 - "Primary chancres on vasectomy wounds."