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Cetylpyridinium (Cetylpyridinium Chloride)

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Cationic bactericidal surfactant used as a topical antiseptic for skin, wounds, mucous membranes, instruments, etc.; and also as a component in mouthwash and lozenges.

Also Known As:

Cetylpyridinium Chloride; Angifonil; Aventis Pharma Brand of Cetylpyridinium Chloride; Biosept; Boots Brand of Cetylpyridinium Chloride; Catamium; Ceepryn Chloride; Cetamium; Cetylpyridium; Cetylyre; Diviser Aquilea Brand of Cetylpyridinium Chloride; Dobendan; Hexadecylpyridinium; Intra Veno Brand of Cetylpyridinium Chloride; Merocets; Pristacin; Pyrisept; Sterogenol; UPSA Conseil Brand of Cetylpyridinium Chloride; Chloride, Ceepryn; Chloride, Cetylpyridinium; Pyridinium, 1-hexadecyl-

Networked: 94 relevant articles (23 outcomes, 19 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Pyridines: 41
    - Pyridinium Compounds: 5
      - Cetylpyridinium: 94
        tserigel: 3
        Fungoid Tincture: 2
        cetylpyridinium chloride drug combination benzoncaine: 1
        Scope mouthwash: 1
        4-vinyl-N-cetylpyridinium
        cetylpyridinium tetrachlorozincate
        Crest Pro-Health mouthrinse
        dexa-phebrocon
        imposit
        TDZ (hemostatic)
        zinc acetate drug combination cetylpyridinium chloride

Experts

1.	Stewart, Bernal: 7 articles (09/2015 - 01/2009)
2.	DeVizio, William: 5 articles (01/2011 - 01/2009)
3.	Mateo, Luis R: 4 articles (09/2015 - 01/2011)
4.	Winkel, E G: 4 articles (09/2015 - 04/2003)
5.	Miller, Jeffrey M: 3 articles (09/2015 - 09/2015)
6.	Pilch, Shira: 3 articles (09/2015 - 09/2015)
7.	Charles, Christine Ann: 3 articles (08/2015 - 07/2009)
8.	Van Winkelhoff, A J: 3 articles (05/2015 - 04/2003)
9.	Sanz, Mariano: 3 articles (11/2013 - 09/2010)
10.	Herrera, David: 3 articles (11/2013 - 09/2010)

Related Diseases

1.	Gingivitis 01/01/1998 - "Thus, the results of this 6-month clinical study support the conclusion that a newly developed mouthrinse containing 0.05% cetylpyridinium chloride provides a statistically significant, clinically relevant level of efficacy for the control of supragingival plaque, and for the control of gingivitis, in accordance with the criteria provided by current ADA guidelines." 11/01/2013 - "Efficacy of a new mouth rinse formulation based on 0.07% cetylpyridinium chloride in the control of plaque and gingivitis: a 6-month randomized clinical trial." 01/01/1998 - "Efficacy of a mouthrinse containing 0.05% cetylpyridinium chloride for the control of plaque and gingivitis: a 6-month clinical study in adults." 05/01/2015 - "Long-term efficacy of a 0.07% cetylpyridinium chloride mouth rinse in relation to plaque and gingivitis: a 6-month randomized, vehicle-controlled clinical trial." 05/01/2012 - "Clinical and microbiological efficacy of an antimicrobial mouth rinse containing 0.05% cetylpyridinium chloride in patients with gingivitis."
2.	Dental Plaque 01/01/2009 - "Clinical investigation of the efficacy of a commercial mouthrinse containing 0.05% cetylpyridinium chloride in preventing dental plaque." 01/01/2009 - "Clinical investigation of the efficacy of a commercial mouthrinse containing 0.05% cetylpyridinium chloride in reducing dental plaque." 11/01/2009 - "A randomized, double-blind clinical study to assess the antimicrobial effects of a cetylpyridinium chloride mouth rinse on dental plaque bacteria." 01/01/1984 - "Effect of a 0.1% cetylpyridinium chloride mouthrinse on the accumulation and biochemical composition of dental plaque in young adults." 01/01/2009 - "A clinical investigation of the efficacy of a commercial mouthrinse containing 0.05% cetylpyridinium chloride to control established dental plaque and gingivitis."
3.	Halitosis 11/01/2013 - "Cetylpyridinium chloride suppresses gene expression associated with halitosis." 11/01/2015 - "Antimicrobial Effectiveness of Cetylpyridinium Chloride and Zinc Chloride-Containing Mouthrinses on Bacteria of Halitosis and Peri-implant Disease." 08/01/2014 - "To investigate the effect of cetylpyridinium chloride buccal tablets on halitosis induced by oral conditions. " 08/01/2014 - "[Effects of cetylpyridinium chloride buccal tablets on halitosis induced by oral conditions]." 08/01/2013 - "This in vitro observation supports the use of chlorhexidine and cetylpyridinium chloride in the treatment of oral halitosis."
4.	Hemorrhage 07/01/2011 - "Cetylpyridinium mouth rinse 0.7% was found to be effective in reducing the bleeding and plaque index scores. " 07/01/2011 - "Paired t test showed significant differences in bleeding index for pre and post treatment recordings for cetylpyridinium group. " 01/01/2005 - "This single-blind, five parallel-arm, four-week randomized clinical trial was designed to compare the efficacy of a 0.05% cetylpyridinium chloride gel-releasing interdental brush (IDB) with standard interproximal cleaning devices for plaque and gingivitis reduction, and decreased frequency in interproximal gingival bleeding. " 09/01/1975 - "Effects of cetylpyridinium chloride containing lozenges on dental plaque and gingival bleeding." 05/01/2015 - "This randomized double-blind in vivo pilot study has evaluated the effects of a toothpaste containing fluoride (control) versus toothpaste containing fluoride, triclosan, cetylpyridinium chloride and essential oils (experimental) in controlling supragingival dental plaque and bleeding on probing in a sample of healthy schoolchildren. "
5.	Pulmonary Tuberculosis 10/01/2013 - "Application of cetylpyridinium chloride and sodium chloride decontamination method for recovery of Mycobacterium tuberculosis from clinically suspected cases of pulmonary tuberculosis." 10/01/2013 - "The study was designed to compare the efficacy of cetylpyridinium chloride (CPC) and sodium chloride (NaCl) decontamination method with N-acetyl L-Cystine (NALC) and sodium hydroxide (NaOH) decontamination (the reference method) method for the recovery of Mycobacterium tuberculosis (MTB) from clinically suspected cases of pulmonary tuberculosis. "

Related Drugs and Biologics

1.	cytidylyl-(3'-5')-cytidine (CpC)
2.	Fluorides
3.	Chlorhexidine
4.	Sodium Fluoride (Ossin)
5.	Triclosan (pHisoHex)
6.	Volatile Oils (Essential Oils)
7.	Zinc
8.	Mouthwashes
9.	Sodium Chloride (Saline Solution)
10.	Sodium Hydroxide (Caustic Soda)

Related Therapies and Procedures

1.	Dental Prophylaxis
2.	Aftercare (After-Treatment)
3.	Toothbrushing
4.	Oral Hygiene (Dental Hygiene)