Uterine Cervical Dysplasia

Abnormal development of immature squamous EPITHELIAL CELLS of the UTERINE CERVIX, a term used to describe premalignant cytological changes in the cervical EPITHELIUM. These atypical cells do not penetrate the epithelial BASEMENT MEMBRANE.

Also Known As:

Networked: 29 relevant articles (0 outcomes, 4 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Infection
2.	Neoplasms (Cancer)
3.	Papillomavirus Infections
4.	Uterine Cervical Neoplasms (Cancer of the Cervix)
5.	Carcinoma in Situ

Experts

1.	Wang, He: 1 article (01/2012)
2.	Liu, Shanling: 1 article (01/2012)
3.	Chen, Xinlian: 1 article (01/2012)
4.	Xie, Xiaoyan: 1 article (01/2012)
5.	Zhang, Xuemei: 1 article (01/2012)
6.	Liu, Hongqian: 1 article (01/2012)
7.	Zhang, Youcheng: 1 article (01/2012)
8.	Morrison, L E: 1 article (12/2006)
9.	Hopman, A H N: 1 article (12/2006)
10.	Herrington, C S: 1 article (12/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Uterine Cervical Dysplasia:

1.	DNA (Deoxyribonucleic Acid)IBA 01/01/1990 - "The present study was attempted to reveal the predictive value of DNA ploidy pattern of uterine cervical dysplasia cases in relation to cervical carcinogenesis. " 11/01/1988 - "A nuclear DNA study of uterine cervical dysplasia with reference to its prognostic significance." 01/01/2000 - "Early progression stage of malignancy of uterine cervical dysplasia as revealed by immunohistochemical demonstration of increased DNA-instability." 02/01/1990 - "[Diagnosis of prospective malignancy of cervix dysplasia using DNA cytometry]." 11/01/1988 - "To further define the nuclear DNA content of uterine cervical dysplasia and its relationship to prognosis and epidemiological features, a retrospective study using Papanicolaou stained cytological specimen and TICAS was undertaken. "
2.	viscum album peptide (Iscador)IBA 10/02/1998 - "One of these trials is using iscador to treat cervix dysplasia, and there is a very high regression of the infection. "
3.	Ascorbic Acid (Vitamin C)FDA LinkGeneric 04/01/1985 - "Plasma vitamin C and uterine cervical dysplasia." 11/01/1981 - "Dietary vitamin C and uterine cervical dysplasia." 01/01/1996 - "The effect of HPV infection on cervix dysplasia development and ascorbic acid level in 528 women was studied. " 01/01/1996 - "[Frequency of HPV infection and the level of ascorbic acid in serum of women with cervix dysplasia]." 01/01/1991 - "Plasma ascorbic acid and beta-carotene levels in women evaluated for HPV infection, smoking, and cervix dysplasia."
4.	Telomerase (Telomerase Reverse Transcriptase)IBA 01/01/2012 - "Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer." 12/01/2006 - "In conclusion, genomic integration of oncogenic HPV and gain of the human telomerase gene TERC appear to be important associated genetic events in the progression of uterine cervical dysplasia to invasive cancer." 12/01/2006 - "Genomic integration of oncogenic HPV and gain of the human telomerase gene TERC at 3q26 are strongly associated events in the progression of uterine cervical dysplasia to invasive cancer."
5.	Interferon Alfa-2c (Interferon Alfa 2c)IBA 01/01/1989 - "[The treatment of virus-associated cervix dysplasia with recombinant interferon alpha-2c or gamma]."
6.	beta Carotene (Betacarotene)FDA Link 01/01/1991 - "Plasma ascorbic acid and beta-carotene levels in women evaluated for HPV infection, smoking, and cervix dysplasia."
7.	Immunologic Factors (Immunomodulators)IBA 01/01/1992 - "[Proposal for the treatment of cervix dysplasia with immunomodulators]."
8.	Immunoglobulins (Immunoglobulin)IBA 01/01/1987 - "Specificity of secretory immunoglobulins in cervical mucus of women with uterine cervical dysplasia."
9.	HeterochromatinIBA 03/01/1980 - "Chromosomal heteromorphism in constitutive heterochromatin of chromosomes 1, 9 and 16 was studied in 8 patients with cervix cancer and 15 patients with cervix dysplasia. "
10.	Glutathione (Reduced Glutathione)IBA 01/01/1995 - "[Frequency of HPV infection and level of glutathione in serum of women with cervix dysplasia]."

Therapies and Procedures

1.	Laser Therapy (Surgery, Laser) 12/01/1988 - "[Cellular changes after laser therapy in mild uterine cervical dysplasia]." 01/01/1985 - "[Laser therapy of cervix dysplasia]." 05/01/1998 - "[The treatment of cervix dysplasia associated with papillomavirus infection by means of laser therapy]."
2.	Lasers (Laser) 10/30/1988 - "[Laser treatment of cervix dysplasia. " 01/01/1983 - "[Laser miniconization - a new method of treating mild and moderate cervix dysplasia]."
3.	Gas Lasers 07/01/1994 - "[The advantages of CO2 laser use in treatment of cervix dysplasia]."
4.	Mud Therapy (Mud Bath) 09/01/1981 - "[Detection of cervix dysplasia during selection of patients for mud therapy]."
5.	Electrocoagulation (Electrocautery) 10/01/1982 - "[Cryogenic surgery of recurrences of cervix dysplasia after electrocoagulation]."