Cerebellar Diseases (Cerebellar Syndrome)

Diseases that affect the structure or function of the cerebellum. Cardinal manifestations of cerebellar dysfunction include dysmetria, GAIT ATAXIA, and MUSCLE HYPOTONIA.
Also Known As:
Cerebellar Syndrome; Cerebellar Disorders; Cerebellar Syndromes; Cerebellar Disease; Cerebellar Disorder; Cerebellar Dysfunctions; Cerebellum Disease; Disease, Cerebellar; Disease, Cerebellum; Disorder, Cerebellar; Dysfunction, Cerebellar; Syndrome, Cerebellar; Cerebellar Dysfunction; Cerebellum Diseases
Networked: 385 relevant articles (16 outcomes, 22 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Bronchogenic Carcinoma
2. Cerebellar Ataxia (Dysmetria)
3. Abducens Nerve Diseases (Sixth Nerve Palsy)
4. Gait Ataxia
5. Polyneuropathies (Polyneuropathy)


1. Strupp, Michael: 4 articles (04/2015 - 01/2008)
2. Stahl, John S: 4 articles (11/2014 - 04/2005)
3. Brandt, Thomas: 3 articles (04/2015 - 01/2008)
4. Walkley, Steven U: 3 articles (02/2015 - 12/2010)
5. Davidson, Cristin: 3 articles (02/2015 - 12/2010)
6. Paulose, C S: 3 articles (07/2011 - 11/2009)
7. Muth, C: 2 articles (09/2015 - 09/2014)
8. Strupp, M: 2 articles (09/2015 - 09/2014)
9. Böttcher, N: 2 articles (09/2015 - 09/2014)
10. Kremmyda, O: 2 articles (09/2015 - 09/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cerebellar Diseases:
1. rituximab (Mabthera)FDA Link
2. Levodopa (L Dopa)FDA LinkGeneric
11/01/2004 - "He has remained responsive to levodopa 14 years after onset and has had no overt signs suggesting cerebellar dysfunction. "
03/01/2004 - "The treatment with l-dopa was effective in patient 3, but non-effective in patient 2. Brain MRI revealed multiple high signal intensities over the subcortical white matter, basal ganglia, and/or even the brainstem in patients 1 and 2, but normal in patient 3. In DAT studies, the bindings were normal in patients 1 and 2 and was decreased in patient 3. We conclude that CS(2) exposure may induce polyneuropathy, and cerebellar dysfunction in addition to parkinsonian features and that brain MRI may show multiple lesions in the cerebral white matter and basal ganglia. "
09/01/2000 - "Difficulties encountered in establishing MSA clinical diagnosis criteria were, among others, the variable expression of the disease, the definition of autonomic failure, of the cerebellar syndrome and of the poor levodopa response of parkinsonism. "
12/01/1995 - "Helpful early points to the diagnosis included rigid-akinetic type, rapid progression, failure to respond to L-DOPA and other signs such as autoromic dysfunction, cerebellar ataxia and pyramidal signs, but these were not always present. "
01/01/2014 - "Though disrupted predictive control is typical of patients with cerebellar disease, sensorimotor deficits associated with the involuntary and often unconscious nature of l-DOPA-induced dyskinesias in Parkinson's disease (PD) suggests dyskinetic subjects may also demonstrate impaired predictive motor control. "
3. Acetazolamide (Diamox)FDA LinkGeneric
4. AntibodiesIBA
5. Episodic ataxia with nystagmusIBA
6. Intravenous Immunoglobulins (IVIG)FDA Link
7. 4-Aminopyridine (4 Aminopyridine)IBA
8. Potassium Channels (Potassium Channel)IBA
9. Estrogens (Estrogen)FDA Link
10. Diazepam (Valium)FDA LinkGeneric

Therapies and Procedures

1. Pneumonectomy (Lung Volume Reduction)
2. Activities of Daily Living (ADL)
3. Transplants (Transplant)
4. Surgical Decompression
5. Craniotomy