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Cephalothin (Cefalotin)

Subscribe to New Research on Cephalothin

A cephalosporin antibiotic.

Also Known As:

Cefalotin; Seffin; Sodium Cephalothin; Cefalotina Normon; Cefalotina Sodica Spaly; Ceftina; Cephalothin Monosodium Salt; Galen Brand of Cephalothin Sodium; Keflin; Lilly Brand of Cephalothin Sodium; Normon Brand of Cephalothin Sodium; Spaly Brand of Cephalothin Sodium; Cephalothin, Sodium; Monosodium Salt, Cephalothin; Salt, Cephalothin Monosodium; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-8-oxo-7-((2-thienylacetyl)amino)-, (6R-trans)-

Networked: 431 relevant articles (43 outcomes, 33 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Venkatesh, Bala: 3 articles (12/2009 - 07/2007)
2.	Dalley, Andrew J: 3 articles (12/2009 - 07/2007)
3.	Cross, Sheree E: 3 articles (12/2009 - 07/2007)
4.	Lipman, Jeffrey: 3 articles (12/2009 - 07/2007)
5.	Roberts, Michael S: 3 articles (12/2009 - 07/2007)
6.	Rudd, Michael: 3 articles (12/2009 - 07/2007)
7.	Pichichero, Michael E: 3 articles (03/2007 - 02/2006)
8.	Deans, Renae: 2 articles (12/2009 - 01/2009)
9.	Kuo, David: 1 article (03/2015)
10.	Ghannoum, Mahmoud: 1 article (03/2015)

Related Diseases

1.	Infection 01/01/1972 - "Its therapeutic efficacy was comparable to that of cephalothin in infections produced by strains of Staphylococcus aureus, Klebsiella pneumoniae, and Proteus mirabilis." 05/01/1987 - "A randomized double-blind placebo-controlled study was performed to determine the efficacy of cephalothin in preventing postoperative shunt infection. " 11/01/1987 - "Cephalothin clearance of Staphylococcus aureus from two experimental infection sites in the presence and absence of local phagocytic cells." 11/01/1987 - "Animals were treated with cephalothin, 100 mg/kg im every 8 h for sixteen doses, beginning 24 h after inoculation of the infection sites with S. " 05/01/1987 - "Sixty-three children who presented for elective VP shunt insertion between January 1982 and December 1985 and who did not have a history of shunt infections were randomly assigned to receive four doses of prophylactic cephalothin, 25 mg/kg (32 patients), or of a multivitamin placebo (31 patients). "
2.	Endocarditis 06/01/1984 - "Whether a strain of methicillin-resistant Staphylococcus aureus susceptible to cephalothin by the disk-diffusion method was also susceptible to cephalothin in vivo was evaluated in the rabbit model of endocarditis. " 03/09/1977 - "Endocarditis due to Citrobacter diversus developing resistance to cephalothin." 04/01/1978 - "The occurrence of cephalothin induced neutropenia in 3 patients with infective endocarditis is described. " 05/01/1981 - "Cefoperazone (10 mg/kg) and cephalothin (20 mg/kg) administered intramuscularly every 6 h were both effective in reducing the number of Staphylococcus aureus cells in vegetations in rabbits with endocarditis. " 01/01/1989 - "We report a case of Stomatococcus mucilaginosus endocarditis in which the isolate was relatively resistant to penicillins and cephalothin. "
3.	Wounds and Injuries (Trauma) 01/01/1976 - "No shift towards cephalothin-resistant strains was observed in isolates from septic wounds in the treatment group." 01/01/1976 - "Achieved levels of cephalothin activity in serum and interstitial water were studied, and the sensitivity of isolated bacteria at the end of operation and from septic wounds was defined. " 05/01/1975 - "Sodium cephalothin levels in the wound drainage were below measurable levels in 3 of 4 patients. " 10/01/1977 - "There was no significant reduction in wound infections in either study in the groups receiving cephalothin, although over two thirds of the organisms cultured from the infected wounds were sensitive to cephalothin. " 01/01/2009 - "The aim of this study was to directly evaluate the influence of burn trauma on the distribution of cephalothin to peripheral tissues. "
4.	Sepsis (Septicemia) 03/01/1968 - "Serratia septicemia during cephalothin therapy." 12/16/1966 - "[Cephalothin in sepsis caused by Salmonella cholerae suis]." 08/01/1977 - "To assay the efficiency of cephalothin prophylaxis in open-heart surgery, bacteriological examination of pressure-measurement units, intravenous catheter tips, and urine were made in 211 consecutive patients as well as blood cultures and sputum in suspected postoperative sepsis. " 08/01/1976 - "The safety and efficacy of tobramycin and cephalothin in treatment of suspected sepsis were studied in neutropenic children with various malignancies. " 03/01/1999 - "Hence, cephalothin remained the antibiotic of first choice in the treatment of CONS septicemia in our unit, with vancomycin selected exclusively for cases not responding to initial cephalothin treatment, or for patients developing CONS septicemia during or after recent cephalothin treatment. "
5.	Osteomyelitis 09/01/1978 - "A recently developed rabbit model for osteomyelitis due to Staphylococcus aureus was used to compare the results of treatment with HBO, cephalothin, a combination of both, or no treatment. " 12/01/1980 - "Although hyperbaric oxygen (HBO) is as effective as cephalothin against osteomyelitis due to Staphylococcus aureus in the rabbit, the effect is not by directing killing. " 01/01/2011 - "We present a case of osteomyelitis requiring prolonged intravenous cephalothin complicated by symptomatic calcium oxalate urocalculi formation. " 04/01/1983 - "Comparative evaluation of cefamandole and cephalothin in the treatment of experimental Staphylococcus aureus osteomyelitis in rabbits." 01/01/1981 - "Authors examined the changes of antibiotic concentration in the inflammatory focus after administering Gentamycin and Cephalothin intravenously or intraarterially in case of experimentally induced osteomyelitis in the tibia of rabbit. "

Related Drugs and Biologics

1.	Gentamicins (Gentamicin)
2.	Tobramycin (Nebcin)
3.	Cefoxitin (Cefoxitin Sodium)
4.	Cefamandole
5.	Ampicillin (Omnipen)
6.	Cephalexin (Cefalexin)
7.	Carbenicillin (Pyopen)
8.	Ceftazidime (Fortum)
9.	Cefotiam
10.	Cefazolin (Ancef)

Related Therapies and Procedures

1.	Continuous Ambulatory Peritoneal Dialysis (CAPD)
2.	Vaginal Hysterectomy
3.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)
4.	Antibiotic Prophylaxis
5.	Transplants (Transplant)