HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Cefotaxime (Kendrick)

Semisynthetic broad-spectrum cephalosporin.

Also Known As:

Kendrick; Cefotaxime Sodium; Claforan; HR756; Aventis Brand of Cefotaxime Sodium; Aventis Pharma Brand of Cefotaxime Sodium; Benaxima; Biosint; Cefotaxim; Cefradil; Cephotaxim; Fotexina; Fustery Brand of Cefotaxime Sodium; Galen Brand of Cefotaxime Sodium; HR-756; Hoechst Brand of Cefotaxime Sodium; Klaforan; Liomont Brand of Cefotaxime Sodium; Merck Brand of Cefotaxime Sodium; Pisa Brand of Cefotaxime Sodium; Primafen; Ru-24756; Taporin; Viken Brand of Cefotaxime Sodium; HR 756; Ru 24756; Ru24756; Sodium, Cefotaxime; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-, monosodium salt, (6R-(6alpha,7beta(Z)))-

Networked: 1430 relevant articles (213 outcomes, 203 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Ko, Wen-Chien: 7 articles (11/2013 - 11/2002)
2.	Cohen, R: 5 articles (11/2013 - 10/2000)
3.	Chuang, Yin-Ching: 5 articles (08/2012 - 11/2002)
4.	Hsueh, Po-Ren: 4 articles (08/2015 - 10/2005)
5.	Wu, Chi-Jung: 4 articles (11/2013 - 10/2005)
6.	Lee, Hsin-Chun: 4 articles (12/2011 - 10/2005)
7.	Lee, Nan-Yao: 4 articles (12/2011 - 10/2005)
8.	Chang, Chia-Ming: 4 articles (12/2011 - 10/2005)
9.	Saxena, Anil K: 3 articles (07/2012 - 11/2005)
10.	Panhotra, Bodh R: 3 articles (07/2012 - 11/2005)

Related Diseases

1.	Infection 10/01/1990 - "Cefotaxime is effective as an empirical treatment of suspected infection due to susceptible organisms in immunocompromised patients and is of proven efficacy in serious, life-threatening infections in general. " 09/03/1982 - "The tissue concentrations were thus high enough to be effective against infections caused by cefotaxim-sensitive organisms. " 01/01/1977 - "Tests on different infection models also provided evidence of the high efficacy of HR 756 in vivo." 05/01/1992 - "We have compared the efficacy of a low dose of cefotaxime (2 g every 12 h) with a more usual dose (2 g every 8 h) in a prospective, randomized study of the treatment of chest infections in the seriously ill. " 05/01/1995 - "In the group with severe infection or severe underlying disease receiving 2 g 12-h cefotaxime, the overall clinical success rate (cured plus improved) was 98.4%. "
2.	Meningitis 02/26/1981 - "Because cefotaxime is active at low concentration and has a good diffusion in the CSF, it provides a particularly effective treatment in Gram-negative meningitis in children. " 01/01/1988 - "Cefotaxime was safe and effective in treating Gram-negative enteric bacillary meningitis in infants and children and should be considered as a potential drug of choice in Gram-negative neonatal meningitis due to susceptible organisms." 09/01/1985 - "Cefotaxime in a dosage of 150 mg/kg/day divided every 6 hours intravenously seems safe and effective therapy for neonatal Gram-negative bacillary meningitis." 03/01/1982 - "Cefotaxime appears to be potentially useful in the management of gram-negative bacillary meningitis." 09/01/1985 - "First clinical signs were noted after 5 days of antibiotherapy (Cefotaxime); at that time the meningitis was cured and the bacteriologic studies yielded negative results. "
3.	Pneumonia (Pneumonitis) 04/01/1986 - "Satisfactory efficacy of cefotaxime in treatment of premature infants with pneumonia during the first month of their life was shown. " 01/01/1992 - "Interim data, however, support the continued use of low-dose cefotaxime as an appropriate alternative for clinically effective and cost-effective management of nosocomially acquired pneumonia." 04/01/1995 - "Streptococcus pneumoniae was eradicated by cefotaxime, and pneumonia resolved. " 01/01/2009 - "The aim of the study was to evaluate therapeutic efficiency of ceftriabol (Russia) and claforan (both 3d generation cefalosporins) used to manage severe extrahospital pneumonia. " 05/01/1995 - "Results from this study support the use of cefotaxime as an alternative to empiric monotherapy for nosocomial pneumonia in surgical-service patients who are not neutropenic or on long-term artificial ventilation."
4.	Bacterial Meningitis 09/01/1984 - "The study demonstrates that cefotaxime is effective in the treatment of acute bacterial meningitis." 09/01/1989 - "Based on this clinical study, cefotaxime is an effective and safe drug for the treatment of childhood bacterial meningitis." 05/01/1995 - "Cefotaxime is an effective and safe drug for the treatment of childhood bacterial meningitis." 07/01/1985 - "Cefotaxime was found to be as safe and effective as standard therapy for the treatment of bacterial meningitis in children." 07/01/1986 - "We conclude that cefotaxime has similar efficacy when compared with conventional therapy for the management of bacterial meningitis in pediatric patients."
5.	Respiratory Tract Infections (Respiratory Tract Infection) 01/01/1988 - "Therapeutic efficacy and tolerability of cefotaxime--a study of acute respiratory infections in chronic lung conditions." 09/01/1984 - "The results of this study indicate that cefotaxime is safe and effective in the therapy of acute bacterial lower respiratory tract infections." 09/01/1982 - "The efficacy of cefotaxime sodium for treatment of patients with lower respiratory infections was evaluated by three protocols in multicenter trials. " 12/01/1998 - "Results from this study support the use of twice-daily cefotaxime administration for the treatment of lower respiratory tract infections in pediatric patients." 06/01/1982 - "This study indicates that cefotaxime realizes significant bronchial amounts superior to MICs of microorganisms responsible for respiratory infections."

Related Drugs and Biologics

1.	Ceftriaxone (Ceftriaxon)
2.	Ciprofloxacin (Cipro)
3.	Ampicillin (Omnipen)
4.	Moxalactam (Latamoxef)
5.	Tobramycin (Nebcin)
6.	Gentamicins (Gentamicin)
7.	Ceftazidime (Fortum)
8.	Cephalosporins (Cephalosporin Antibiotics)
9.	Vancomycin
10.	Metronidazole (Metric)

Related Therapies and Procedures

1.	Intensive Care (Surgical Intensive Care)
2.	Catheters
3.	Drug Therapy (Chemotherapy)
4.	Cesarean Section (Caesarean Section)
5.	Hysterectomy