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Cefadroxil (Duricef)

Long-acting, broad-spectrum, water-soluble, CEPHALEXIN derivative.

Also Known As:

Duricef; Ultracef; 4-Hydroxycephalexin; BL-S 578; BL-S578; Bidocef; Cephadroxyl; S-578; S578; 4 Hydroxycephalexin; BL S 578; BL S578; BLS 578; BLS578; S 578; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, (6R-(6alpha,7beta(R*)))-

Networked: 173 relevant articles (38 outcomes, 40 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Keep, Richard F: 4 articles (12/2013 - 12/2005)
2.	Smith, David E: 4 articles (12/2013 - 12/2005)
3.	Naberhuis-Stehouwer, Sharon: 3 articles (09/2003 - 04/2003)
4.	Skogerboe, Terry L: 2 articles (01/2009 - 08/2008)
5.	Chesebrough, Robert: 2 articles (01/2009 - 08/2008)
6.	Six, Robert: 2 articles (01/2009 - 08/2008)
7.	Papp, Georg: 2 articles (01/2009 - 08/2008)
8.	Lindeman, Cindy J: 2 articles (01/2009 - 08/2008)
9.	Stegemann, Michael R: 2 articles (01/2009 - 08/2008)
10.	Boucher, Joseph F: 2 articles (01/2009 - 08/2008)

Related Diseases

1.	Infection 03/01/1980 - "(3) Cefadroxil may be expected to be a highly effective and safe agent for the therapy of otorhinolaryngological infections." 02/01/1981 - "In respiratory tract, skin and gingival infections, cefadroxil was either 'excellent' or 'effective' in all 7 patients. " 12/01/2005 - "Cefadroxil is a cephalosporin antibiotic used in the treatment of infection. " 01/01/1987 - "30 patients with persistent mainly secondary urinary infection were treated with cephadroxyl. " 01/01/1987 - "[Treatment of urinary infection with cephadroxyl (Pharmachem)--microbiological and clinical research]."
2.	Pharyngitis (Sore Throat) 01/01/1988 - "The results of this study indicate that cefadroxil given once daily for streptococcal pharyngitis is an effective and well-tolerated antimicrobial agent, and suggest that the desirable pharmacokinetic properties of cefadroxil contribute to this efficacy." 09/01/1986 - "Once daily therapy for streptococcal pharyngitis with cefadroxil." 01/01/1980 - "Efficacy and safety of cefadroxil in bacterial pharyngitis." 02/01/1981 - "1. Cefadroxil was administered at a daily dose of 30 mg/kg divided into 3 times in 24 cases of acute tonsillitis and pharyngitis, and clinical results were obtained; remarkably excellent in 8 cases, good in 13 cases, and poor in 3 cases. " 07/01/1994 - "A separate meta-analysis performed by Deeter et al reported that the oral cephalosporin cefadroxil monohydrate achieved significantly greater bacteriologic cure rates (94.8% cefadroxil vs 87.5% penicillin, P < 0.05) than oral penicillin when 9 trials in 1406 patients with streptococcal pharyngitis were analyzed. "
3.	Respiratory Tract Infections (Respiratory Tract Infection) 01/01/1986 - "Efficacy of a twice-daily regimen of cefadroxil in the treatment of respiratory tract infections." 09/01/1991 - "These bacteriologic data, together with results of pharmacologic studies (long half-life and good penetration within tissues) can explain the clinical successes obtained with cefadroxil in ENT and lower respiratory tract infections." 01/01/1986 - "This multicentre open study evaluated the responses of 474 adult and paediatric patients with upper or lower respiratory tract infections to treatment with cefadroxil (25 to 50 mg/kg in children and 500 mg to 1 g in adults) twice daily for 10 to 30 days. " 03/01/1987 - "[Clinical and bacteriological evaluation of the effectiveness of cefadroxil in the treatment of respiratory tract infections]." 03/01/1986 - "[Use of cefadroxil in respiratory tract infections in children]."
4.	Pyoderma 01/01/1993 - "Cefadroxil Once Daily Pyoderma Study Group." 05/01/1991 - "Pyoderma caused by Peptostreptococcus tetradius in a pup was successfully treated with cefadroxil. " 09/01/1989 - "Once daily cefadroxil therapy for pyoderma." 08/15/1993 - "We compared efficacy of cefadroxil and generic and proprietary cephalexin in treatment of pyoderma in dogs. " 08/15/1993 - "Comparison of the efficacy of cefadroxil and generic and proprietary cephalexin in the treatment of pyoderma in dogs."
5.	Pneumonia (Pneumonitis) 07/01/1993 - "We report the case of a 3 year old asthmatic child who was hospitalized for superimposed pneumonia and was included in a study evaluating cefadroxil. " 01/01/1980 - "Cefadroxil in the treatment of lobar pneumonia." 01/01/1993 - "These results show that Cefadroxil is effective in reducing antigen-induced bronchial hyperresponsiveness, an effect independent of a reduction in the pulmonary inflammation, namely eosinophil accumulation in lung." 07/01/1986 - "Therapeutic efficacy of cefadroxil and cephalexin for pneumonia in a rat test model." 08/01/1983 - "Thirty-four patients with community-acquired acute pneumonias were treated in a prospective, randomized trial with either cefadroxil, 500 mg twice daily, or cephalexin, 250 mg four times daily. "

Related Drugs and Biologics

1.	Cephalexin (Cefalexin)
2.	Penicillins (Penicillin)
3.	Penicillin V (Phenoxymethylpenicillin)
4.	cefuroxime axetil (Ceftin)
5.	Cefaclor (Ceclor)
6.	Cephalosporins (Cephalosporin Antibiotics)
7.	Ampicillin (Omnipen)
8.	Amoxicillin (Wymox)
9.	cefovecin
10.	Suspensions

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Oral Administration