Divalent Cations

01/01/2022 - "ZAJ-2c was characterized with high binding ability independent of the presence of divalent cations at a temperature range from 4 to 37 °C, showing promise for measuring the expression of CD49c on cancer cells. "
07/01/1985 - "Effects of divalent cations on the interaction of platelets with tumor cells: aggregation and perfusion studies with two homologous human systems."
03/01/1991 - "Furthermore, the observation that tumour cells grown in culture are influenced by external divalent cations confirms the involvement of Mg2+ in cancer as well as in normal cell proliferation. "
01/01/1988 - "The presence of divalent cations and plasma factors was necessary for the cancer cells to exert their activating capacity. "
04/14/1987 - "Furthermore, the broadening and splitting of individual signals were also noted with tumor-bearing mice; this is interpreted as indicating a variety of changes in chemical shift occurring in the brain of the animals due to heterogeneous distribution of pH. Binding or detaching of divalent cations to and from phosphometabolites may also be responsible for these changes."

03/01/1982 - "Therefore 133Ba2+ flux studies were used to delineate the effects of hypoxia and reoxygenation on sarcolemmal permeability to divalent cations. "
01/01/2012 - "Several types of stress, such as hypoxia, exposure to farnesol or elevated concentrations of certain divalent cations, trigger a differentiation in A. "
06/01/1984 - "The relationship between creatine phosphokinase (CPK) release and sarcolemmal permeability to divalent cations (Ca2+ and Ba2+) during hypoxia and reoxygenation was studied in the isolated arterially perfused septal preparation of the newborn and adult rabbit. "
03/15/2012 - "Manganese and iron, which are known to regulate the release of other divalent cations from sub-oxic sediments, were released from sediments at all sites as hypoxia developed. "
01/30/1999 - "Pharmacological blocking agents which are relatively selective for L- (verapamil, diltiazem, nifedipine) and N- (omega-conotoxin GVIA) type calcium channels were significantly protective against anoxia-induced loss of conduction, as was non-specific block using divalent cations. "

04/08/2005 - "The thermo-protective effects of various concentrations of trehalose in mycoplasma growth medium, various concentrations of trehalose in the dehydration stabilizer and the importance of some divalent cations were assessed. "
06/15/2004 - "The comparative analysis of the dehydration effects suggests that the divalent cations bind to the polynucleotides in inner-sphere manner. "
01/01/1999 - "However, the dehydration energies of cations clearly explain the selectivity for monovalent versus divalent cations. "
01/01/2020 - "All atomistic MD simulations quantitatively reveal that the divalent cations in solution lead to more interchain electrostatic cross-links between peptide chains, especially for peptides with block charges, which causes dehydration of the zwitterionic peptides and diminishes their antifouling performances."
06/15/2004 - "In the case of single-helical poly(rA) binding is more specific: dehydration effects correspond to three to five direct contacts and must involve atomic groups of adenines, and the divalent cations stabilize and aggregate the polynucleotide."

01/01/2014 - "It has been reported that host-encoded mammalian RNA molecules and divalent cations play a role in the pathogenesis of prion diseases, and RNA molecules have also been shown to improve the sensitivity of PMCA assays. "
09/01/2006 - "Interaction of metals with prion protein: possible role of divalent cations in the pathogenesis of prion diseases."
11/15/2012 - "Recent evidence indicates that PrP is a metalloprotein since the octapeptide repeat sequences in the protein have high affinity for various divalent cations and the binding sites appear to play a role in the pathogenesis of prion diseases. "
03/03/2009 - "Divalent cations, such as zinc and copper, have allosteric effects on misfolded aggregates of comparable neurodegenerative disorders including Alzheimer disease, prion diseases, and ALS. "

06/01/2001 - "Divalent cations in women with PCOS: implications for cardiovascular disease."
03/01/1994 - "The resulting relationships between divalent cations and hypertrophy were presented to draw attention to areas which remain unexplored with perspective to cardiovascular disease."
01/01/2022 - "Background EDTA is an intravenous chelating agent with high affinity to divalent cations (lead, cadmium, and calcium) that may be beneficial in the treatment of cardiovascular disease (CVD). "