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Catechin (Z 7300)

An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.

Also Known As:

Z 7300; Epicatechin; Cianidanol; (+)-Catechin; (+)-Cyanidanol; (+)-Cyanidanol-3; 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R-cis)-; 3,3',4',5,7-Flavanpentol; Catergen; Cyanidanol-3; KB-53; Zyma; Acid, Catechinic; Acid, Catechuic; Cyanidanol 3; KB 53; KB53; Catechinic Acid; Catechuic Acid; 2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-, (2R-trans)-

Networked: 702 relevant articles (60 outcomes, 134 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- Pyrans: 5
  - Benzopyrans: 11
    - Chromones: 27
      - Flavonoids: 2256
        Catechin: 702
        epigallocatechin gallate: 891
        gallocatechol: 140
        procyanidin: 86
        polyphenon E: 47
        epicatechin gallate: 46
        theaflavin: 33
        oligonol: 24
        procyanidin B2: 22
        flavocoxid: 21
        SP 303: 10
        catechin gallate: 8
        procyanidin B3: 6
        procyanidol oligomer: 5
        gallocatechin gallate: 4
        theaflavin digallate: 4
        thearubigin: 4
        Veregen: 4
        epigallocatechin-(4-8,2-O-7)epicatechin: 3
        3-O-methylcatechin: 2
        4'-O-methylepigallocatechin: 2
        epiafzelechin: 2
        procyanidin B: 2
        procyanidin B1: 2
        Capsibiol-T: 1
        Diprim: 1
        epicatechin sulfate: 1
        Eucatex: 1
        procyanidin B5: 1
        procyanidin B5-3'-gallate: 1
        Rhodopes: 1
        (4beta-8)-7-O-beta-D-xylopyranosyl-epicatechin
        3'-O-cinnamoylprocyanidin A-2
        3'-O-methylcatechin
        3'-O-methylepicatechin
        3,3',4,4',7-flavanpentol
        3,5,7,3',4'-Pentaacetyl catechin
        3-O-(3,4,5-trimethoxybenzoyl)epicatechin
        3-O-(3-methylgalloyl)catechin
        3-O-galloylepicatechin-4b,8-3-O-galloylcatechin
        3-O-octanoyl-catechin
        3-palmitoylcatechin
        3-propionylcatechin
        4',4''-di-O-methyl-EGCG
        4-(2-aminoethylthio)epicatechin
        4-(2-aminoethylthio)epicatechin 3-O-gallate
        4-(S-cysteinyl)catechin
        4-(S-cysteinyl)epicatechin 3-O-gallate
        6-chloroepicatechin
        7-O-beta-D-xylopyranosyl-epicatechin
        8,8-methylmethine catechin
        8-vinylcatechin
        aesculitannin C
        amurensisin
        benzotropolone
        bis-fisetinidol-(4alpha-6,4alpha-8)catechin 3-gallate
        catechin sulfate
        catechin-(5,6-bc)-4beta-(4''-hydroxyphenyl)-dihydro-2(H)-pyranone
        catiguanin A
        catiguanin B
        dehydrotheasinensin A
        dideoxy-epigallocatechin gallate
        ent-epiafzelechin-(4alpha-8)epiafzelechin
        epicatechin 5-gallate
        epicatechin dimer B2
        epicatechin-(4beta-8)-epicatechin-(4beta-8,2beta-O-7)-epicatechin-(4beta-8)-epicatechin
        epicatechin-(4beta-8,2beta-O-7)-epicatechin-(4beta-8)-epicatechin
        epicatechin-2-sulfonate sodium salt
        epicatechin-3'-O-glucuronide
        epicatechin-glucuronide
        epigallocatechin gallate 7-O-alpha-D-glucopyranoside
        epigallocatechin-3-(3''-O-methyl)gallate
        epigeoside
        fisetinidol-(4alpha-8)catechin 3-gallate
        galactopyranosylepicatechin (2-7,4-8)epicatechin
        gallocatechin-(4-8)-catechin
        gallocatechin-(4-8)-gallocatechin
        gallocatechin-(4-8)-gallocatechin-(4-8)-catechin
        gallocatechin-7-gallate
        heptyl-3-catechin
        P183-1
        parabaroside A
        parabaroside B
        parabaroside C
        peracetylated epigallocatechin-3-gallate
        pro-F-EGCG2
        pro-F-EGCG4
        procyanidin A1
        procyanidin A2
        procyanidin B5 3'-O-gallate
        procyanidin C
        procyanidin D
        pyranomalvidin-3-glucoside-catechin
        SR 13193
        theacitrin C
        theaflavine gallate
        vitisinol
        vitisinol D
    - Chromans: 1
      - Catechin: 702
        epigallocatechin gallate: 891
        gallocatechol: 140
        procyanidin: 86
        polyphenon E: 47
        epicatechin gallate: 46
        theaflavin: 33
        oligonol: 24
        procyanidin B2: 22
        flavocoxid: 21
        SP 303: 10
        catechin gallate: 8
        procyanidin B3: 6
        procyanidol oligomer: 5
        gallocatechin gallate: 4
        theaflavin digallate: 4
        thearubigin: 4
        Veregen: 4
        epigallocatechin-(4-8,2-O-7)epicatechin: 3
        3-O-methylcatechin: 2
        4'-O-methylepigallocatechin: 2
        epiafzelechin: 2
        procyanidin B: 2
        procyanidin B1: 2
        Capsibiol-T: 1
        Diprim: 1
        epicatechin sulfate: 1
        Eucatex: 1
        procyanidin B5: 1
        procyanidin B5-3'-gallate: 1
        Rhodopes: 1
        (4beta-8)-7-O-beta-D-xylopyranosyl-epicatechin
        3'-O-cinnamoylprocyanidin A-2
        3'-O-methylcatechin
        3'-O-methylepicatechin
        3,3',4,4',7-flavanpentol
        3,5,7,3',4'-Pentaacetyl catechin
        3-O-(3,4,5-trimethoxybenzoyl)epicatechin
        3-O-(3-methylgalloyl)catechin
        3-O-galloylepicatechin-4b,8-3-O-galloylcatechin
        3-O-octanoyl-catechin
        3-palmitoylcatechin
        3-propionylcatechin
        4',4''-di-O-methyl-EGCG
        4-(2-aminoethylthio)epicatechin
        4-(2-aminoethylthio)epicatechin 3-O-gallate
        4-(S-cysteinyl)catechin
        4-(S-cysteinyl)epicatechin 3-O-gallate
        6-chloroepicatechin
        7-O-beta-D-xylopyranosyl-epicatechin
        8,8-methylmethine catechin
        8-vinylcatechin
        aesculitannin C
        amurensisin
        benzotropolone
        bis-fisetinidol-(4alpha-6,4alpha-8)catechin 3-gallate
        catechin sulfate
        catechin-(5,6-bc)-4beta-(4''-hydroxyphenyl)-dihydro-2(H)-pyranone
        catiguanin A
        catiguanin B
        dehydrotheasinensin A
        dideoxy-epigallocatechin gallate
        ent-epiafzelechin-(4alpha-8)epiafzelechin
        epicatechin 5-gallate
        epicatechin dimer B2
        epicatechin-(4beta-8)-epicatechin-(4beta-8,2beta-O-7)-epicatechin-(4beta-8)-epicatechin
        epicatechin-(4beta-8,2beta-O-7)-epicatechin-(4beta-8)-epicatechin
        epicatechin-2-sulfonate sodium salt
        epicatechin-3'-O-glucuronide
        epicatechin-glucuronide
        epigallocatechin gallate 7-O-alpha-D-glucopyranoside
        epigallocatechin-3-(3''-O-methyl)gallate
        epigeoside
        fisetinidol-(4alpha-8)catechin 3-gallate
        galactopyranosylepicatechin (2-7,4-8)epicatechin
        gallocatechin-(4-8)-catechin
        gallocatechin-(4-8)-gallocatechin
        gallocatechin-(4-8)-gallocatechin-(4-8)-catechin
        gallocatechin-7-gallate
        heptyl-3-catechin
        P183-1
        parabaroside A
        parabaroside B
        parabaroside C
        peracetylated epigallocatechin-3-gallate
        pro-F-EGCG2
        pro-F-EGCG4
        procyanidin A1
        procyanidin A2
        procyanidin B5 3'-O-gallate
        procyanidin C
        procyanidin D
        pyranomalvidin-3-glucoside-catechin
        SR 13193
        theacitrin C
        theaflavine gallate
        vitisinol
        vitisinol D
- 2-Ring Heterocyclic Compounds
  - Benzopyrans: 11
    - Chromones: 27
      - Flavonoids: 2256
        Catechin: 702
        epigallocatechin gallate: 891
        gallocatechol: 140
        procyanidin: 86
        polyphenon E: 47
        epicatechin gallate: 46
        theaflavin: 33
        oligonol: 24
        procyanidin B2: 22
        flavocoxid: 21
        SP 303: 10
        catechin gallate: 8
        procyanidin B3: 6
        procyanidol oligomer: 5
        gallocatechin gallate: 4
        theaflavin digallate: 4
        thearubigin: 4
        Veregen: 4
        epigallocatechin-(4-8,2-O-7)epicatechin: 3
        3-O-methylcatechin: 2
        4'-O-methylepigallocatechin: 2
        epiafzelechin: 2
        procyanidin B: 2
        procyanidin B1: 2
        Capsibiol-T: 1
        Diprim: 1
        epicatechin sulfate: 1
        Eucatex: 1
        procyanidin B5: 1
        procyanidin B5-3'-gallate: 1
        Rhodopes: 1
        (4beta-8)-7-O-beta-D-xylopyranosyl-epicatechin
        3'-O-cinnamoylprocyanidin A-2
        3'-O-methylcatechin
        3'-O-methylepicatechin
        3,3',4,4',7-flavanpentol
        3,5,7,3',4'-Pentaacetyl catechin
        3-O-(3,4,5-trimethoxybenzoyl)epicatechin
        3-O-(3-methylgalloyl)catechin
        3-O-galloylepicatechin-4b,8-3-O-galloylcatechin
        3-O-octanoyl-catechin
        3-palmitoylcatechin
        3-propionylcatechin
        4',4''-di-O-methyl-EGCG
        4-(2-aminoethylthio)epicatechin
        4-(2-aminoethylthio)epicatechin 3-O-gallate
        4-(S-cysteinyl)catechin
        4-(S-cysteinyl)epicatechin 3-O-gallate
        6-chloroepicatechin
        7-O-beta-D-xylopyranosyl-epicatechin
        8,8-methylmethine catechin
        8-vinylcatechin
        aesculitannin C
        amurensisin
        benzotropolone
        bis-fisetinidol-(4alpha-6,4alpha-8)catechin 3-gallate
        catechin sulfate
        catechin-(5,6-bc)-4beta-(4''-hydroxyphenyl)-dihydro-2(H)-pyranone
        catiguanin A
        catiguanin B
        dehydrotheasinensin A
        dideoxy-epigallocatechin gallate
        ent-epiafzelechin-(4alpha-8)epiafzelechin
        epicatechin 5-gallate
        epicatechin dimer B2
        epicatechin-(4beta-8)-epicatechin-(4beta-8,2beta-O-7)-epicatechin-(4beta-8)-epicatechin
        epicatechin-(4beta-8,2beta-O-7)-epicatechin-(4beta-8)-epicatechin
        epicatechin-2-sulfonate sodium salt
        epicatechin-3'-O-glucuronide
        epicatechin-glucuronide
        epigallocatechin gallate 7-O-alpha-D-glucopyranoside
        epigallocatechin-3-(3''-O-methyl)gallate
        epigeoside
        fisetinidol-(4alpha-8)catechin 3-gallate
        galactopyranosylepicatechin (2-7,4-8)epicatechin
        gallocatechin-(4-8)-catechin
        gallocatechin-(4-8)-gallocatechin
        gallocatechin-(4-8)-gallocatechin-(4-8)-catechin
        gallocatechin-7-gallate
        heptyl-3-catechin
        P183-1
        parabaroside A
        parabaroside B
        parabaroside C
        peracetylated epigallocatechin-3-gallate
        pro-F-EGCG2
        pro-F-EGCG4
        procyanidin A1
        procyanidin A2
        procyanidin B5 3'-O-gallate
        procyanidin C
        procyanidin D
        pyranomalvidin-3-glucoside-catechin
        SR 13193
        theacitrin C
        theaflavine gallate
        vitisinol
        vitisinol D
    - Chromans: 1
      - Catechin: 702
        epigallocatechin gallate: 891
        gallocatechol: 140
        procyanidin: 86
        polyphenon E: 47
        epicatechin gallate: 46
        theaflavin: 33
        oligonol: 24
        procyanidin B2: 22
        flavocoxid: 21
        SP 303: 10
        catechin gallate: 8
        procyanidin B3: 6
        procyanidol oligomer: 5
        gallocatechin gallate: 4
        theaflavin digallate: 4
        thearubigin: 4
        Veregen: 4
        epigallocatechin-(4-8,2-O-7)epicatechin: 3
        3-O-methylcatechin: 2
        4'-O-methylepigallocatechin: 2
        epiafzelechin: 2
        procyanidin B: 2
        procyanidin B1: 2
        Capsibiol-T: 1
        Diprim: 1
        epicatechin sulfate: 1
        Eucatex: 1
        procyanidin B5: 1
        procyanidin B5-3'-gallate: 1
        Rhodopes: 1
        (4beta-8)-7-O-beta-D-xylopyranosyl-epicatechin
        3'-O-cinnamoylprocyanidin A-2
        3'-O-methylcatechin
        3'-O-methylepicatechin
        3,3',4,4',7-flavanpentol
        3,5,7,3',4'-Pentaacetyl catechin
        3-O-(3,4,5-trimethoxybenzoyl)epicatechin
        3-O-(3-methylgalloyl)catechin
        3-O-galloylepicatechin-4b,8-3-O-galloylcatechin
        3-O-octanoyl-catechin
        3-palmitoylcatechin
        3-propionylcatechin
        4',4''-di-O-methyl-EGCG
        4-(2-aminoethylthio)epicatechin
        4-(2-aminoethylthio)epicatechin 3-O-gallate
        4-(S-cysteinyl)catechin
        4-(S-cysteinyl)epicatechin 3-O-gallate
        6-chloroepicatechin
        7-O-beta-D-xylopyranosyl-epicatechin
        8,8-methylmethine catechin
        8-vinylcatechin
        aesculitannin C
        amurensisin
        benzotropolone
        bis-fisetinidol-(4alpha-6,4alpha-8)catechin 3-gallate
        catechin sulfate
        catechin-(5,6-bc)-4beta-(4''-hydroxyphenyl)-dihydro-2(H)-pyranone
        catiguanin A
        catiguanin B
        dehydrotheasinensin A
        dideoxy-epigallocatechin gallate
        ent-epiafzelechin-(4alpha-8)epiafzelechin
        epicatechin 5-gallate
        epicatechin dimer B2
        epicatechin-(4beta-8)-epicatechin-(4beta-8,2beta-O-7)-epicatechin-(4beta-8)-epicatechin
        epicatechin-(4beta-8,2beta-O-7)-epicatechin-(4beta-8)-epicatechin
        epicatechin-2-sulfonate sodium salt
        epicatechin-3'-O-glucuronide
        epicatechin-glucuronide
        epigallocatechin gallate 7-O-alpha-D-glucopyranoside
        epigallocatechin-3-(3''-O-methyl)gallate
        epigeoside
        fisetinidol-(4alpha-8)catechin 3-gallate
        galactopyranosylepicatechin (2-7,4-8)epicatechin
        gallocatechin-(4-8)-catechin
        gallocatechin-(4-8)-gallocatechin
        gallocatechin-(4-8)-gallocatechin-(4-8)-catechin
        gallocatechin-7-gallate
        heptyl-3-catechin
        P183-1
        parabaroside A
        parabaroside B
        parabaroside C
        peracetylated epigallocatechin-3-gallate
        pro-F-EGCG2
        pro-F-EGCG4
        procyanidin A1
        procyanidin A2
        procyanidin B5 3'-O-gallate
        procyanidin C
        procyanidin D
        pyranomalvidin-3-glucoside-catechin
        SR 13193
        theacitrin C
        theaflavine gallate
        vitisinol
        vitisinol D

Experts

1.	Ceballos, Guillermo: 9 articles (12/2014 - 08/2008)
2.	Villarreal, Francisco: 7 articles (12/2014 - 08/2008)
3.	Hara, Yukihiko: 7 articles (10/2009 - 02/2002)
4.	Oteiza, Patricia I: 6 articles (07/2015 - 10/2006)
5.	Yang, Chung S: 6 articles (03/2015 - 04/2003)
6.	Ramirez-Sanchez, Israel: 6 articles (12/2014 - 09/2011)
7.	Chopra, Kanwaljit: 6 articles (05/2014 - 11/2003)
8.	Taub, Pam R: 6 articles (01/2014 - 06/2010)
9.	Hase, Tadashi: 6 articles (09/2013 - 06/2007)
10.	Tokimitsu, Ichiro: 6 articles (04/2013 - 06/2007)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2014 - "The objectives of this study were to evaluate the potential of (-)-epicatechin to stimulate mitochondrial respiration in cancer cells and to selectively sensitize cancer cells to radiation. " 10/01/2005 - "Various studies have shown significant suppressive effects of catechin on mammalian cells, either tumor or normal cells, including lymphoid cells. " 01/01/2005 - "In additional studies, catechin, the main monomeric polyphenol of red wine, delayed tumor onset in this mouse model in a positive, linear relationship when incorporated into the diet at levels of 0.5-4 mmol/kg diet. " 07/01/2003 - "These studies were guided by assays of the putative catechin-vanilloid target protein tNOX, a cell surface growth-related enzymatic activity specific to cancer. " 10/01/2002 - "No significant effects on tumor onset were observed when mice consumed a diet supplemented with wine solids containing <0.22 mmol catechin/kg diet, whereas a previous study showed that wine solids with a similar total polyphenol concentration but containing approximately 4 times more catechin significantly delayed tumor onset by approximately 30 d compared with a control diet. "
2.	Inflammation 04/01/2011 - "The nanocatechin group showed statistically significant decrease in bacterial growth and improvement in prostatic inflammation compared with the catechin group. " 08/01/2012 - "The objective of this study was to assess the catechin effect in GRX liver cells in activities such as cell growth and inflammation. " 07/01/2012 - "The current study was intended to evaluate the hepatoprotective effect of Epicatechin (EC) against radiation-induced oxidative stress, in terms of inflammation and lipid peroxidation. " 01/01/2012 - "This study was pathway of (-)-epicatechin (EC) in the prevention and treatment of intestine inflammation in acute and chronic rat models. " 01/01/2015 - "Moreover, (+)-catechin blocked the activation of Akt and its inhibition was shown to play a crucial role in LPS-induced inflammation in BV-2 microglial cells. "
3.	Hepatitis 11/01/1983 - "Induction of hepatitis did not affect the fast clearance of unchanged 3-O-methyl-(+)-catechin from plasma but plasma clearance of the metabolites was reduced from 112 to 89 ml/hr." 01/01/1987 - "For in vivo studies, HBV hepatitis patients were treated with cianidanol at a daily dose of 3.0 g cianidanol for seven days and were investigated before and after the treatment. " 10/01/1977 - "[A double-blind clinical study of the effect of a new molecule (+)-cyanidanol-3 on the course of the clinical symptoms and biological parameters of viral hepatitis]." 01/01/1987 - "Chronic HBV hepatitis patients showed a moderate decrease in NK cell activity compared to the controls, but after the cianidanol therapy their NK cell activity significantly rose to 68.0% +/- 9.5% (p less than 0.01). " 07/15/1985 - "["Catergen" in the treatment of hepatitis]."
4.	Breast Neoplasms (Breast Cancer) 01/01/2001 - "Our data showed that mixed GTE and its individual catechin components were effective in inhibiting breast cancer and endothelial cell proliferation. " 04/01/2010 - "In conclusion, high epicatechin may be related to a reduced risk of breast cancer. " 04/01/2010 - "In spline regression, we found an overall dose-response relationship between epicatechin level and risk of breast cancer, although it was not apparent in low and middle urinary excretion range. " 04/01/2010 - "Urinary excretion of epicatechin was inversely associated with breast cancer risk [odds ratio (OR) and 95% confidence interval (CI) of 0.59 (0.39-0.88) for the intermediate tertile]. " 01/01/2008 - "Here we report an innovative enzymatic strategy for the oligomerization of catechins (specifically epicatechin) that yields stable, water-soluble oligomerized epicatechins with enhanced and highly specific anti-proliferative activity for human breast cancer cells. "
5.	Obesity 01/01/2011 - "The purpose of this research is to determine whether the specially manufactured GSE, catechin-rich GSE (CGSE), can protect against obesity induced by a high-fat diet (HFD) and to address the mechanism underlying this effect. " 06/01/2008 - "These findings suggest that ingestion of a catechin-rich beverage ameliorates serious obesity and cardiovascular disease risk factors without raising any safety concerns in Japanese children." 07/01/2009 - "These findings suggest that multiple effects of catechins, including anti-obesity and anti-cancer effects, are mediated, at least in part, by the activation of LKB1/AMPK in various tissues, and that these effects vary according to the catechin structure." 01/01/2012 - "This study compared the effect of RTP on biochemical and molecular markers of oxidative stress to equimolar doses (0.66 mmol) of RES and catechin-rich grape seed extract (CGSE) in a model of oxidative and metabolic stress associated with obesity in humans. " 03/01/2012 - "Green tea catechin has been proposed to have an anti-obesity effect. "

Related Drugs and Biologics

1.	Tea
2.	Catechin (Z 7300)
3.	epigallocatechin gallate (epigallocatechin-3-gallate)
4.	Insulin (Novolin)
5.	Flavonoids
6.	Glutathione (Reduced Glutathione)
7.	Ciprofloxacin (Cipro)
8.	Gallic Acid
9.	epigallocatechin-(4-8,2-O-7)epicatechin
10.	Caffeine (No Doz)

Related Therapies and Procedures

1.	Oral Administration
2.	Root Planing
3.	Homologous Transplantation (Allograft)
4.	Heterologous Transplantation (Xenotransplantation)
5.	Home Nursing (Nursing, Home)