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Caseins (Casein)

A mixture of related phosphoproteins occurring in milk and cheese. The group is characterized as one of the most nutritive milk proteins, containing all of the common amino acids and rich in the essential ones.

Also Known As:

Casein; beta-Casein; AD beta-Casein; Acetylated, Dephosphorylated beta-Casein; Casein A; K-Casein; Sodium Caseinate; alpha(S1)-Casein; alpha(S1)-Casein A; alpha(S1)-Casein B; alpha(S1)-Casein C; alpha(S2)-Casein; alpha-Caseins; beta-Caseins; epsilon-Casein; gamma-Caseins; kappa-Casein; kappa-Caseins; AD beta Casein; Caseinate, Sodium; K Casein; alpha Caseins; beta Casein; beta Caseins; beta-Casein Acetylated, Dephosphorylated; beta-Casein, AD; epsilon Casein; gamma Caseins; kappa Casein; kappa Caseins

Networked: 1726 relevant articles (70 outcomes, 167 trials/studies)

Relationship Network

Drug Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Dietary Proteins: 1551
    - Milk Proteins: 1092
      - Caseins: 1726
        ameroid: 162
        casein hydrolysate: 81
        trypticase-soy broth: 70
        proteose-peptone: 50
        casein phosphopeptide-amorphous calcium phosphate nanocomplex: 43
        caseinomacropeptide: 27
        azocasein: 23
        Osmolite: 10
        thyroactive iodinated casein: 10
        calcium caseinate: 6
        pregestimil: 6
        methylated casein: 3
        caseins and magnesium hydroxide barium sulfate mixt. with calcium hydroxide: 1
        dentacal: 1
        isracidin: 1
        N,N-dimethylcasein: 1
        4-methylumbelliferyl-casein
        acetylcasein
        alpha(S1)-casein (1-197)
        alpha(S1)-casein (136-196)
        alpha(S1)-casomorphin
        alpha(S1)-casomorphin amide
        alpha(S2)-casein (164-179)
        alpha(S2)-casein (183-207)
        alpha-casein (142-149)
        alpha-casein (59-79)
        alpha-casein (90-95)
        beta-casein (1-105)
        beta-casein (1-42)
        beta-casein F (133-138)
        beta-casokinin 10
        BODIPY-alpha-casein
        Bos taurus PP3 protein
        caseinophosphopeptide 1-25
        casocidin I
        casoxin C
        FF 5005
        fluorescein thiocarbamoyl casein
        human BCLP protein
        human lactaptin
        kappa-casein glycomacropeptide
        kappa-caseinoglycopeptide
        KNQDK peptide
        neo-cholex powder
        rat casein-like phosphoprotein
        testosterone-3-carboxymethyloxime-casein
        topacal C-5
  - Phosphoproteins: 284
    - Caseins: 1726

Experts

1.	Sugiyama, Kimio: 10 articles (05/2015 - 10/2002)
2.	Simmen, Rosalia C M: 10 articles (11/2013 - 12/2004)
3.	Ruan, Xiong Z: 9 articles (01/2015 - 09/2008)
4.	Sampson, Hugh A: 9 articles (01/2015 - 04/2002)
5.	Moorhead, John F: 9 articles (01/2015 - 09/2008)
6.	Chen, Yaxi: 9 articles (01/2015 - 09/2008)
7.	Varghese, Zac: 9 articles (01/2015 - 09/2008)
8.	Yolken, Robert H: 8 articles (02/2015 - 05/2010)
9.	Zhao, Lei: 8 articles (01/2015 - 01/2011)
10.	Badger, Thomas M: 8 articles (09/2013 - 11/2002)

Related Diseases

1.	Neoplasms (Cancer) 04/01/1995 - "Whey and casein diets were more protective against the development of intestinal tumors than were the red meat or soybean diets, as evidenced by a reduced incidence of rats affected (P = 0.15), fewer tumors per treatment group (burden, P < 0.005), and a reduced pooled area of tumors (tumor mass index) that formed (P = 0.39). " 01/01/2006 - "The selenised casein diet at this concentration was effective in reducing colon tumor incidence (by 29%) and burden (decreased 52%, P < 0.05) relative to the control in rats 26 wk post-induction. " 04/01/1983 - "PMNs obtained 6 hr after casein injection were effective against tumor target cells but those obtained 3 hr after the injection were not. " 01/01/2006 - "The efficacy of selenised casein and indeed other potential dietary sources deserve further investigation with regard to their ability to prevent colon tumors at concentrations considered safe in the diet." 05/01/1998 - "A diet containing chickpeas and wheat offers less protection against colon tumors than a casein and wheat diet in dimethylhydrazine-treated rats."
2.	Body Weight (Weight, Body) 05/01/1977 - "Although daily intakes of diet throughout the study were significantly lower than those of rats maintained on a normal protein diet (25% casein) or stock diet, intakes/100 g body weight were significantly greater. " 10/01/1993 - "In the casein diet period, body weight gain was almost the same in GF and Cvd rats, but food intake was significantly greater in Cvd than in GF rats. " 01/01/2013 - "Whey significantly reduced body weight gain during the first four weeks of the study compared with casein (P<0.001-0.05). " 06/01/1982 - "In experiment 2, a similar study was conducted except that the 25 and 49% casein diets were fed ad libitum, and body weight gain was allowed. " 09/01/2013 - "Casein-fed fish similarly had significantly reduced body length, body weight, and lean and fat mass in both male and female fish, with a low percent body fat compared with other diets (leanest). "
3.	Autistic Disorder (Autism) 01/01/2015 - "These actions may provide a potential contributing mechanism for the beneficial effects of a casein-free diet in alleviating gastrointestinal symptoms in neurological conditions including autism and other conditions. " 01/01/2015 - "Casein-free, gluten-free diets have been reported to mitigate some of the inflammatory gastrointestinal and behavioral traits associated with autism, but the mechanism for this palliative effect has not been elucidated. " 05/01/2008 - "Bone development, casein-free diet use, supplements, and medications were assessed for 75 boys with autism or autism spectrum disorder, ages 4-8 years. " 11/01/2015 - "Most investigations assessing the efficacy of a gluten-free and casein-free diet in the treatment of autism are seriously flawed. " 04/01/2006 - "This study tested the efficacy of a gluten-free and casein-free (GFCF) diet in treating autism using a randomized, double blind repeated measures crossover design. "
4.	Weight Gain 08/01/1983 - "Autoclaving to very low TI values made no improvement in weight gain or pancreatic parameters measured, indicating that there may be a threshold level of TI below which rat pancreata do not respond, and that other factors in SPI are responsible for the slight pancreatic enlargement seen with SPI compared to casein." 12/01/1983 - "Significant improvement in weight gain in comparison with that recorded for larvae fed the unsupplemented casein diet could not be demonstrated when ground hulls of Tower or Candle were added to this diet. " 11/01/1984 - "Animals on the protein-free vs. 55% casein regimen exhibited a lower weight gain, a lower cumulative energy intake and a greater cumulative total protein intake during the 13-day study compared to rats selecting between 15% and 55% casein. " 11/01/1981 - "Long-term (3+ months) studies in four infants showed that 50% calories and 80% protein from wheat (casein added to 8% protein calories) supported weight gain and linear growth more than expected. " 12/14/2013 - "In comparison with casein, the effects of WPI on energy intake and hypothalamic and adipose tissue gene expression may thus represent a state of reduced susceptibility to weight gain on a HFD."
5.	Hypersensitivity (Allergy) 01/01/2006 - "Comparing extensively hydrolysed casein containing formula with cow's milk formula, one study (431 infants) reported a significant reduction in childhood allergy incidence (RR 0.72, 95% CI 0.53, 0.97). " 10/12/1985 - "The use of a RAST was especially helpful in diagnosing milk-cheese-casein allergies." 01/01/2011 - "This study aimed to characterize the role of phosphorylation of caseins in selective allergy to goat milk (GM) and sheep milk (SM) in patients with good tolerance to cow milk (CM). " 04/01/2010 - "Children with a familial predisposition for allergy whose parents agreed to participate in the prospective, double-blind intervention trial (N=2252) were randomly assigned at birth to one of four formulas: partially or extensively hydrolysed whey, extensively hydrolysed casein (eHF-C) or standard cow's milk formula. " 11/01/2000 - "[Study on casein allergy in children]."

Related Drugs and Biologics

1.	Soybean Proteins (Soy Protein)
2.	Glutens (Glutelin)
3.	amorphous calcium phosphate
4.	whey protein
5.	casein phosphopeptide-amorphous calcium phosphate nanocomplex (Recaldent)
6.	Cholesterol
7.	Methionine (L-Methionine)
8.	Threonine (L-Threonine)
9.	Glucose (Dextrose)
10.	Fluorides

Related Therapies and Procedures

1.	Oral Hygiene (Dental Hygiene)
2.	Protein-Restricted Diet (Diet, Protein Restricted)
3.	Enteral Nutrition (Feeding, Tube)
4.	Drug Therapy (Chemotherapy)
5.	Aftercare (After-Treatment)