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Carticaine (Articaine)

A thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.

Also Known As:

Articaine; Articain; Carticain; Carticaine Hydrochloride; Hoe-045; Hoe-40045; Hoechst Brand of Carticaine Hydrochloride; Ultracaine; Hoe 045; Hoe 40045; Hoe045; Hoe40045; Hydrochloride, Carticaine; 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester

Networked: 133 relevant articles (32 outcomes, 34 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Reader, Al: 5 articles (09/2015 - 01/2004)
2.	Nusstein, John: 5 articles (09/2015 - 01/2004)
3.	Beck, Mike: 5 articles (09/2015 - 01/2004)
4.	Aggarwal, Vivek: 3 articles (06/2013 - 07/2009)
5.	Allman, K G: 3 articles (02/2004 - 10/2001)
6.	Leblanc, D: 3 articles (02/2001 - 05/2000)
7.	Gagnon, S: 3 articles (02/2001 - 05/2000)
8.	Malamed, S F: 3 articles (02/2001 - 05/2000)
9.	Drum, Melissa: 2 articles (09/2015 - 03/2009)
10.	McDonald, Neville J: 2 articles (06/2014 - 05/2011)

Related Diseases

1.	Pulpitis 09/01/2015 - "The aim of this study was to compare the efficacy of 1.8 mL and 3.6 mL articaine for an inferior alveolar nerve block (IANB) when treating molars with symptomatic irreversible pulpitis. " 01/01/2014 - "Study of the anesthetic efficacy of inferior alveolar nerve block using articaine in irreversible pulpitis." 01/01/2012 - "Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with symptomatic versus asymptomatic irreversible pulpitis." 08/01/2004 - "Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with irreversible pulpitis." 11/01/2015 - "This systematic review of double-blind, randomized clinical trials provides level 1 evidence to support the use of articaine for patients with symptomatic irreversible pulpitis. "
2.	Pain (Aches) 06/01/2011 - "For this latter procedure, the pain-related behaviour score was 1.5- times higher in the prilocain-anaesthetised children than in the articaine-anaesthetised children. " 05/01/2011 - "It can be concluded that articaine seems to be a more appropriate anesthetic for the extraction of mandibular third molars due to the shorter duration of the anesthetic effect in the soft tissues, lower pain reported by patients during the immediate postoperative period and the personal preference of patients for this drug." 07/01/2000 - "Pain ratings: Articaine: VAS (Visual Analogue Scale) scores (from 0 to 10 cm) by patients 4 to < 13 years of age were 0.5 for simple procedures and 1.1 for complex procedures, and average investigator scores were 0.4 and 0.6 for simple and complex procedures, respectively. " 06/01/1974 - "[Carticaine in the therapie of pain (author's transl)]." 09/01/2015 - "Buffered articaine did not provide any advantage over nonbuffered articaine for anesthetic success, anesthesia onset, or pain of injection for a primary buccal infiltration of the mandibular first molar."
3.	Cataract (Cataracts) 10/01/2004 - "Articaine for sub-Tenon's and peribulbar anaesthesia in cataract surgery." 03/01/2002 - "This prospective double-blind randomized study comprised 200 cataract patients assigned to 1 of 2 groups of 100 each based on type of anesthesia: carticaine 4% or lidocaine 2%. " 04/01/2008 - "Articaine (4%) is a safer and a superior anaesthetic agent than a mixture of 2% lidocaine and 0.5% levobupicaine in achieving ocular akinesia for sub-Tenon's block in phacoemulsification cataract surgery." 03/01/2002 - "To compare carticaine 4% and lidocaine 2% for peribulbar anesthesia in cataract surgery. " 03/01/2002 - "Carticaine versus lidocaine for peribulbar anesthesia in cataract surgery."
4.	Paresthesia (Dysesthesia) 01/01/2013 - "The results suggest that articaine is not toxic to the nervous structure and further studies are necessary to explain the possible relation between articaine injection and paresthesia." 01/01/2009 - "The 'question' about an increased risk of paresthesia following articaine administration via IANB has been answered by careful evaluation of case reports. " 12/01/2006 - "Despite an increase in anecdotal reports of paresthesia since articaine's introduction there is yet, no supporting scientific evidence." 01/01/2006 - "This article reviews the epidemiological evidence regarding articaine and paresthesia." 01/01/2006 - "Articaine and paresthesia: epidemiological studies."
5.	Postoperative Pain 05/01/2011 - "Regarding efficacy, patients experienced less postoperative pain at 6 and 12 hours and shorter duration of soft tissue anesthesia with articaine. " 01/01/2012 - "In the present study no significant differences were observed between lidocaine and articaine in the control of postoperative pain." 05/01/2012 - "Bupivacaine could be a valid alternative to articaine especially due to its early postoperative pain prevention ability." 05/01/2011 - "With regard to the preference of patients, it was higher for articaine, the main reasons being the greater postoperative pain and swelling with bupivacaine. " 03/01/2002 - "The mean onset of postoperative pain was 2.00 +/- 0.86 hours in the lidocaine group and 5.52 +/- 1.80 hours in the carticaine group (P <.05). "

Related Drugs and Biologics

1.	Lidocaine (Xylocaine)
2.	Epinephrine (Adrenaline)
3.	Bupivacaine (Bupivacaine Hydrochloride)
4.	Prilocaine (Citanest)
5.	Ketorolac
6.	Mepivacaine (Carbocaine)
7.	Pain-Free
8.	Anesthetics (Anesthetic Agents)
9.	Dexamethasone (Maxidex)
10.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)

Related Therapies and Procedures

1.	Anesthesia
2.	Pulpectomy
3.	Injections
4.	Local Anesthesia
5.	Phacoemulsification