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Carotid Body Tumor

Benign paraganglioma at the bifurcation of the COMMON CAROTID ARTERIES. It can encroach on the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies.
Also Known As:
Carotid Body Tumors; Carotid Body Paraganglioma; Carotid Body Paragangliomas; Paragangliomas, Carotid Body; Tumor, Carotid Body; Tumors, Carotid Body; Paraganglioma, Carotid Body
Networked: 179 relevant articles (4 outcomes, 10 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Paraganglioma (Paragangliomas)
3. Wounds and Injuries (Trauma)
4. Cranial Nerve Injuries
5. Glomus Jugulare Tumor

Experts

1. Pacak, Karel: 3 articles (01/2021 - 07/2003)
2. Karemaker, John M: 3 articles (06/2004 - 03/2002)
3. Lenders, Jacques W M: 3 articles (06/2004 - 03/2002)
4. Timmers, Henri J L M: 3 articles (06/2004 - 03/2002)
5. Wieling, Wouter: 3 articles (06/2004 - 03/2002)
6. Carrafiello, Gianpaolo: 2 articles (04/2022 - 01/2021)
7. Hohenstatt, Sophia: 2 articles (04/2022 - 01/2021)
8. Ierardi, Anna Maria: 2 articles (04/2022 - 01/2021)
9. Paolucci, Aldo: 2 articles (04/2022 - 01/2021)
10. Dralle, H: 2 articles (01/2019 - 12/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Carotid Body Tumor:
1. Hormones (Hormone)IBA
11/01/1985 - "Ten of the 11 carotid body tumors demonstrated immunoreactivity for multiple hormones. "
01/01/1985 - "All 18 cases demonstrated immunostaining for NSE; 10 of the 11 carotid body tumors had immunostaining for multiple hormones. "
10/13/2021 - "Paragangliomas (PGLs) are benign hypervascular tumors that can develop in head and neck at different locations, primarily in the carotid bifurcation, jugular bulb, tympanic plexus, and vagal ganglia.1 Different gene mutations have been linked to the familial inherited forms, which can represent approximately 30% of all PGLs.1,2 These are classified into 5 different clinical syndromes: PGL 1 to 5.1 These patients have increased risk for synchronous and metachronous lesions requiring an extensive work-up for hormone secretion and other associated neoplasms, as well as attentive follow-up for lifelong management.1,3 Surgical resection is the best treatment option as it can be curative when the resection is total.2-4 Preservation of the lower cranial nerve function is central to the management of head and neck PGLs, given the gravity of bilateral injuries.3 Irradiation therapy should be considered if the risk for bilateral lower cranial nerve injuries is high.5 Surgically, intrabulbar resection with preservation of the medial wall of the jugular bulb protects the lower cranial nerve function.3 Other technical finesses, including maintaining the facial nerve in its bony fallopian canal (facial bridge), avoiding carotid artery sacrifice, preservation of the ear canal, and preoperative embolization, contributed markedly to outcome improvement.2,3 We report a case of a 34-yr-old male with PGL 3 with a left glomus jugulare tumor that recurred and a right carotid body tumor. "
2. lutetium Lu 177 dotatateIBA
3. Succinate Dehydrogenase (Fumarate Reductase)IBA
4. Chromogranin AIBA
5. pentetreotide (OctreoScan)FDA Link
6. ethylene-vinyl alcohol copolymerIBA
7. Phosphopyruvate Hydratase (Enolase)IBA
8. IndiumIBA
9. gallium Ga 68 dotatateIBA
10. CatecholaminesIBA

Therapies and Procedures

1. Therapeutics
2. Radiotherapy
3. Operative Surgical Procedures
4. Vascular Surgical Procedures
5. Prostheses and Implants (Prosthesis)