Cardiac Tamponade

Compression of the heart by accumulated fluid (PERICARDIAL EFFUSION) or blood (HEMOPERICARDIUM) in the PERICARDIUM surrounding the heart. The affected cardiac functions and CARDIAC OUTPUT can range from minimal to total hemodynamic collapse.

Also Known As:

Networked: 1259 relevant articles (41 outcomes, 40 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Pericardial Effusion
2.	Pericarditis
3.	Neoplasms (Cancer)
4.	Constrictive Pericarditis
5.	Hemorrhage

Experts

1.	Aneman, A: 5 articles (02/2009 - 07/2000)
2.	Takala, Jukka: 4 articles (01/2013 - 01/2002)
3.	Imazio, Massimo: 4 articles (08/2012 - 03/2004)
4.	Ristić, Arsen D: 3 articles (01/2011 - 05/2003)
5.	Seferović, Petar M: 3 articles (01/2011 - 05/2003)
6.	Maisch, Bernhard: 3 articles (01/2011 - 05/2003)
7.	De Backer, D: 3 articles (10/2001 - 10/2000)
8.	Vincent, J L: 3 articles (10/2001 - 10/2000)
9.	French Society of Cardiology: 2 articles (11/2015 - 02/2010)
10.	Takagi, H: 2 articles (10/2015 - 01/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cardiac Tamponade:

1.	Cisplatin (Platino)FDA LinkGeneric 04/30/1987 - "Intracavitary cisplatin in malignant cardiac tamponade." 08/01/2006 - "[A case of pericardial tamponade caused by recurrent breast cancer treated with intrapericardial and intrapleural infusion of cisplatin (CDDP)]." 01/01/2004 - "Evaluation of intrapericardial cisplatin administration in cases with recurrent malignant pericardial effusion and cardiac tamponade." 01/01/1996 - "[Evaluation of intrapericardial cisplatin administration in cases of recurrent malignant pericardial effusion and cardiac tamponade]." 06/01/1997 - "The aim of this study was to evaluate the effectiveness and side-effects of intrapericardial administration of cisplatin (IAC), in cases of abundant malignant pericardial effusion (MPE) and/or cardiac tamponade occurring in the course of adenocarcinoma of the lung (AL). "
2.	salicylhydroxamic acid (SHAM)IBA 01/01/1982 - "Of the 7 patients on sham exchange, 3 improved by more than 10 points (26, 15, and 16), 3 remained unchanged (-5, 4, and 8) and 1 was not able to complete the study due to cardiac tamponade. " 10/01/1991 - "The fall in mean arterial pressure with cardiac tamponade was significantly greater in splenectomized dogs than in either sham-operated or control dogs (P less than 0.001). " 10/01/1991 - "The percent increase in hematocrit from baseline to the third stage of cardiac tamponade was 19.6 +/- 9.8 and 22.3 +/- 5.6% in control and sham dogs, respectively. " 10/01/1991 - "Hematocrit increased significantly with cardiac tamponade in controls and sham-operated but not splenectomized dogs. " 10/01/1991 - "Cardiac output was more depressed at the third level of cardiac tamponade in splenectomized than in sham-operated or control dogs (12.8 +/- 14.5 vs. 29.3 +/- 8.7 and 25.4 +/- 9.4 ml.min-1.kg-1, respectively; both P less than 0.05 vs. splenectomy). "
3.	ColchicineFDA LinkGeneric 03/02/2002 - "[Spectacular efficacy of colchicine in a beginning cardiac tamponade]." 11/01/2015 - "In total, 13 cases of cardiac tamponade occurred during the 14-day treatment (7 and 6 in the placebo and colchicine groups, respectively; p=0.80). " 04/01/2012 - "Secondary end points were symptom persistence after 72 h, remission rate at 1 week, number of recurrences, time to first recurrence, disease-related hospitalizations,cardiac tamponade, and constrictive pericarditis rates.120 patients (60 in the colchicine and 60 in the placebo group) were included in the analysis. " 11/01/2015 - "In patients with pericardial effusion after cardiac surgery, colchicine administration does not reduce the effusion volume or prevent late cardiac tamponade. " 01/01/2012 - "This case presents UCTD as a rare cause of cardiac tamponade and large pericardial effusions and suggests that colchicine can be used to treat UCTD-associated effusions. "
4.	OxygenIBA 06/01/1993 - "Systemic oxygen extraction can be improved during repeated episodes of cardiac tamponade." 03/01/2001 - "Thirty minutes later, cardiac tamponade was introduced to study organ perfusion and tissue oxygen extraction capabilities. " 10/01/2000 - "Cardiac tamponade was then induced by saline injection in the pericardial sac to progressively reduce cardiac index and thereby allow study of tissue oxygen extraction capabilities. " 07/01/1993 - "The present study used a model of cardiac tamponade to investigate the effects of endotoxin on the oxygen extraction capabilities of the body during an acute reduction in blood flow, when blood volume and arterial oxygen content were maintained. " 03/01/2008 - "Mixed venous oxygen saturation in the diagnosis of cardiac tamponade."
5.	AclarubicinIBA 08/01/1999 - "To determine the efficacy of aclarubicin hydrochloride in local control of malignant pericardial effusion, the authors carried out a trial of pericardial drainage with local administration of this agent in five patients, whose effusions had produced cardiac tamponade. "
6.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 11/01/2013 - "Retrograde wire passage using a septal collateral is the preferred route as the consequences of vessel perforation are more benign than epicardial collateral perforation which may produce cardiac tamponade. " 01/01/2011 - "We should also note that time elapsed from the vessel cannulation to cardiac tamponade first signs does not preclude this procedure as a cause of this fatal complications." 02/01/1999 - "This vessel retracted into the pericardial sac where it bled causing a pericardial tamponade." 01/01/2014 - " believe that in our patient an injury of a nutritional pericardial or descending aorta vessel caused by the Lima stitch resulted in oozing bleeding, which gradually leaded to cardiac tamponade. " 04/01/1993 - "Nine patients had a major complication resulting directly from vessel perforation (cardiac tamponade, myocardial infarction or need for bypass surgery) and 14 had no clinical complications after successful sealing of the puncture site. "
7.	Adenocarcinoma of lungIBA 01/01/2014 - "Recurrent cardiac tamponade: an initial presentation of lung adenocarcinoma." 05/01/2008 - "A 53-year-old man presented with cardiac tamponade due to direct invasion of left atrium by a large cell neuroendocrine metastatic lung adenocarcinoma. " 09/01/2005 - "Twenty-five patients (19 males and 6 females, median age 55 years) with lung adenocarcinoma confirmed by cytological examination and cardiac tamponade were studied. " 12/08/1990 - "We report three patients with lung adenocarcinoma clinically presenting as cardiac tamponade. " 01/01/2014 - "Pericardial tamponade and coexisting pulmonary embolism as first manifestation of non-advanced lung adenocarcinoma."
8.	SteroidsIBA 07/01/1977 - "Intrapericardial steroids in treatment of rheumatoid pericardial tamponade." 02/01/2014 - "Therefore, in children presenting with cardiac tamponade, systemic lupus erythematosus should be considered as one of the differential diagnoses, as morbidity and mortality associated with cardiac tamponade can be dramatically reduced with early diagnosis and use of steroids. " 01/01/2011 - "Neuroendocrine carcinoma presenting as cardiac tamponade and dramatic response to steroids." 02/01/2014 - "We present a case of DILE presenting with cardiac tamponade associated with infliximab use that resolved with discontinuation of the medication and administration of high-dose steroids. " 06/01/2010 - "Despite pharmacological treatment with nonsteroidal anti-inflammatory drugs, steroids, diuretics and antibiotics the symptoms of cardiac tamponade occurred. "
9.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/2013 - "The patient, who developed cardiac tamponade shortly after admission, experienced a rapid resolution of symptoms following pericardial drainage and initiation of antibiotics." 02/01/1992 - "A five year old girl with cardiac tamponade due to purulent pericarditis caused by Staphylococcus aureus was treated successfully with a combination therapy of appropriate antibiotics and surgical open drainage. " 05/01/2010 - "He was treated with antibiotics and anticoagulation, and his course was complicated by hemorrhagic pericarditis and cardiac tamponade. " 08/01/1993 - "An 88 year old woman with streptococcal pneumonia developed purulent pericarditis and cardiac tamponade despite treatment with antibiotics. " 06/01/2010 - "Despite pharmacological treatment with nonsteroidal anti-inflammatory drugs, steroids, diuretics and antibiotics the symptoms of cardiac tamponade occurred. "
10.	Methotrexate (Mexate)FDA LinkGeneric 10/01/2001 - "This case suggests that intrapericardial application of methotrexate may be very useful in the management of carcinomatous cardiac tamponade without any serious side effects." 12/01/1996 - "More on pericardial tamponade during methotrexate therapy." 10/01/2001 - "Pericardiocentesis followed by methotrexate instillation 6 times in a dose of 110 mg successfully controlled the cardiac tamponade, after which the catheter could be removed from the pericardial space. " 07/01/1995 - "Accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate therapy." 05/01/1994 - "Accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate therapy."

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 01/01/2013 - "Due to the recurrence of the life-threatening cardiac tamponade, video-assisted thoracoscopic pericardial fenestration was performed and systemic chemotherapy was introduced with good results." 05/01/2003 - "Intrapericardial chemotherapy may be effective in the management of cardiac tamponade secondary to malignancy." 01/01/1992 - "In all cases, systemic chemotherapy or hormonal therapy was started after the pericardial tamponade was cured. " 03/01/2007 - "While systemic chemotherapy (CAF) was started after admission,she presented with cardiac tamponade. " 11/28/2005 - "However, three cases who underwent systemic chemotherapy survived for more than 10 mo. Cases that developed metachronous cardiac tamponade for more than 2 years after the diagnosis of GC generally survived for a longer period of time, although this was not statistically significant. "
2.	Catheters 06/01/1998 - "A significant reduction in myocardial temperature, without the development of cardiac tamponade, can be attained using a pericardial catheter to cool the pericardial space. " 01/01/1996 - "Percutaneous catheter drainage is an effective treatment for pediatric oncology patients with pericardial tamponade. " 01/01/1996 - "Cardiac tamponade was effectively treated in all patients and did not recur with percutaneous catheter drainage alone. " 01/01/1995 - "Ultrasound-guided pigtail catheter drainage is a minimally invasive, safe and effective method for the palliation of cardiac tamponade in patients with malignant pericardial disease." 05/01/1983 - "Bedside hemodynamic studies with a Swan-Ganz catheter confirmed the diagnosis of pericardial tamponade. "
3.	Pericardiectomy 02/01/1983 - "We had four patients with neoplastic cardiac tamponade who were treated successfully with subxiphoid pericardiotomy and pericardial drainage. " 07/01/1990 - "Immediate relief from acute cardiac tamponade was obtained in all except one patient, who was treated by pericardiotomy because of insufficient drainage. " 09/01/2015 - "This study involved 90 consecutive patients (58 males and 32 females) with a mean age of 57.4 ± 14.1 years, who underwent emergent pericardiotomy in the years 2006 to 2011 due to symptomatic primary cardiac tamponade. " 09/01/2015 - "Pericardiotomy, although invasive, is a safe method to relieve cardiac tamponade. " 09/01/2015 - "Early and long-term outcomes of pericardiotomy in the treatment of primary cardiac tamponade."
4.	Thoracotomy 04/01/2015 - "Resuscitative thoracotomy for nontraumatic pericardial tamponade: case reports and review of the literature." 02/01/2013 - "A 67-year-old patient with severe comorbidities and acute type A aortic dissection with pericardial tamponade was treated with an endograft introduced through a mini-thoracotomy and puncture of the left ventricular apex. " 04/01/2012 - "A smaller pericardial incision than is traditionally used during ED thoracotomy deserves further consideration and research to determine whether and when it may be most useful as a temporizing treatment of cardiac tamponade when other methods have failed." 04/01/2012 - "Modified emergency department thoracotomy for postablation cardiac tamponade." 05/01/2011 - "We describe acute pericardial tamponade in a young man who underwent left posterolateral thoracotomy for left upper lobectomy. "
5.	Stents 04/01/1997 - "Following stent implantation, the patient developed cardiac tamponade, treated successfully with percutaneous pericardiocentesis and autologous platelet administration." 01/01/2014 - "Delayed cardiac tamponade after stent fracture." 10/01/2013 - "Biliary stent migration as a cause of cardiac tamponade." 09/01/2012 - "Here we report a rare case of a patient who developed coronary perforation during PCI for the CTO lesion and suffered from delayed cardiac tamponade due to collateral flow from the contralateral coronary artery despite complete hemostasis of the perforated site by the covered stent." 06/01/2012 - "The mean stent size was 3.51 ± 0.67 mm and the mean stent length was 20.3 ± 4.4 mm. There was 1 case of in-hospital death due to cardiac tamponade. "