Carbonic Acid

Carbonic acid (H2C03). The hypothetical acid of carbon dioxide and water. It exists only in the form of its salts (carbonates), acid salts (hydrogen carbonates), amines (carbamic acid), and acid chlorides (carbonyl chloride). (From Grant & Hackh's Chemical Dictionary, 5th ed)

Also Known As:

Networked: 84 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Schwartz, G J: 2 articles (01/2007 - 06/2000)
2.	Kourehpaz, Zohreh: 1 article (12/2015)
3.	Mohammadipour Anvari, Hassan: 1 article (12/2015)
4.	Movassaghi, Reza: 1 article (12/2015)
5.	Aghamohammadi, Davood: 1 article (12/2015)
6.	Peirovifar, Ali: 1 article (12/2015)
7.	Golzari, Samad Ej: 1 article (12/2015)
8.	Taghavi, Seyed Mohammad: 1 article (09/2015)
9.	Amidon, Gregory E: 1 article (09/2015)
10.	Amidon, Gordon L: 1 article (09/2015)

Related Diseases

1.	Dehydration (Water Stress) 09/01/2015 - "Assuming carbonic acid is irreversible in the dehydration direction: CO2 + H2 O ← H2 CO3 , the transport analysis can accurately predict rotating disk dissolution of weak acid and weak base drugs in bicarbonate buffer. " 06/01/1986 - "The kinetic rate-determining step for this reaction is the dehydration of carbonic acid. " 06/01/1982 - "During a bicarbonate diuresis, final urine Pco2 considerably exceeds systemic Pco2, an effect thought to reflect the postpapillary delayed dehydration of carbonic acid. " 05/01/1977 - "The rise in urine PCO2 due to phosphate could be the result of either (1) a distal mechanism, by affecting the delayed dehydration of carbonic acid, or (2) an increase in the medullary PCO2. " 10/01/1969 - "The effect of delayed dehydration of carbonic acid on renal bicarbonate clearance, and its significance for acid-base balance."
2.	Neoplasms (Cancer) 07/01/2005 - "Carbonic anhydrase IX (MN/Ca9) catalyses the reversible metabolism of carbon dioxide to carbonic acid and has also been linked to malignant transformation and hypoxia in various cancers. " 12/01/2004 - "Carbonic anhydrase (CA) IX, an endogenous marker for tumor hypoxia, catalyzes the hydration of carbon dioxide into carbonic acid and contributes to the pH regulation of tumor cells. " 03/01/2015 - "However, hyperglycemia substantially increases lactic acid production in tumors by a factor of approximately six (p < 0.05), but hyperglycemia did not increase the effects of LND on acidification of the tumor, most probably because of the strong buffering action of carbon dioxide (the pKa of carbonic acid is 6.4). " 04/01/2010 - "One of these proteins is carbonic anhydrase IX (CA IX), which catalyzes the reversible hydration of carbon dioxide to carbonic acid outside the cell, leading to an acidic extracellular pH and a physiological intracellular pH. The aim of this article was to study semiquantitatively the expression of CA IX in non-small cell lung cancer (NSCLC) and to assess the existence of a possible relationship between CA IX expression and tumor FDG uptake, reflecting glucose metabolism. "
3.	Myocardial Infarction 01/01/1975 - "The ballistocardiographic studies conducted with a diagnostic purpose indicate that carbonic acid balneotherapy may be used in patients after the third month following the onset of myocardial infarction. "
4.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/01/2010 - "One of these proteins is carbonic anhydrase IX (CA IX), which catalyzes the reversible hydration of carbon dioxide to carbonic acid outside the cell, leading to an acidic extracellular pH and a physiological intracellular pH. The aim of this article was to study semiquantitatively the expression of CA IX in non-small cell lung cancer (NSCLC) and to assess the existence of a possible relationship between CA IX expression and tumor FDG uptake, reflecting glucose metabolism. "
5.	Anoxia (Hypoxia) 01/01/1958 - "[Sensitivity of individual impulseforming centers of the heart toward carbonic acid and hypoxia]." 01/01/2008 - "On this level of hypoxia such effect is highly important, as unchecked strengthening of respiration activating mechanisms may result in excessive hyperventilation and consequent respiration slowing down to standstill because of low blood content of carbonic acid. " 06/01/1999 - "Blood gas measurements of WA1-infected mice showed reduced oxygen saturation and pH, and increased carbonic acid compared to controls, indicating hypoxia and respiratory acidosis. " 07/01/2005 - "Carbonic anhydrase IX (MN/Ca9) catalyses the reversible metabolism of carbon dioxide to carbonic acid and has also been linked to malignant transformation and hypoxia in various cancers. " 12/01/2004 - "Carbonic anhydrase (CA) IX, an endogenous marker for tumor hypoxia, catalyzes the hydration of carbon dioxide into carbonic acid and contributes to the pH regulation of tumor cells. "

Related Drugs and Biologics

1.	Carbonic Anhydrases (Carbonic Anhydrase)
2.	Carbon Dioxide
3.	Proteins (Proteins, Gene)
4.	Sodium Bicarbonate (Baking Soda)
5.	Hydrochloric Acid (Hydrogen Chloride)
6.	Glucose (Dextrose)
7.	Phenobarbital (Luminal)
8.	Carbon Monoxide
9.	Lactic Acid
10.	Protons (Proton)

Related Therapies and Procedures

1.	Balneology
2.	Baths
3.	Vagotomy
4.	Lasers (Laser)
5.	Laser Therapy (Surgery, Laser)