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Carbon Monoxide Poisoning (Poisoning, Carbon Monoxide)

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Toxic asphyxiation due to the displacement of oxygen from oxyhemoglobin by carbon monoxide.

Also Known As:

Poisoning, Carbon Monoxide; Poisoning, Illuminating Gas; Carbon Monoxide Poisonings; Gas Poisoning, Illuminating; Gas Poisonings, Illuminating; Illuminating Gas Poisonings; Monoxide Poisoning, Carbon; Monoxide Poisonings, Carbon; Poisonings, Carbon Monoxide; Poisonings, Illuminating Gas; Illuminating Gas Poisoning

Networked: 799 relevant articles (19 outcomes, 45 trials/studies)

Relationship Network

Disease Context: Research Results

Substance-Related Disorders: 9381
- Poisoning: 26707
  - Gas Poisoning: 114
    - Carbon Monoxide Poisoning: 799

Related Diseases

1.	Air Embolism (Gas Embolism)
2.	Gas Gangrene (Gangrene, Gas)
3.	Burns
4.	Wounds and Injuries (Trauma)
5.	Parkinsonian Disorders (Parkinsonism)

Experts

1.	Hampson, Neil B: 9 articles (03/2013 - 03/2002)
2.	Weaver, Lindell K: 7 articles (07/2014 - 10/2002)
3.	Kuriiwa, Fumi: 6 articles (03/2012 - 07/2003)
4.	Hara, Shuichi: 6 articles (03/2012 - 07/2003)
5.	Mukai, Toshiji: 6 articles (03/2012 - 07/2003)
6.	Hopkins, Ramona O: 6 articles (11/2007 - 10/2002)
7.	Yip, Paul S F: 5 articles (04/2014 - 01/2007)
8.	Kurosaki, Kunihiko: 5 articles (09/2011 - 07/2003)
9.	Thom, Stephen R: 5 articles (01/2010 - 10/2002)
10.	Brvar, Miran: 4 articles (02/2015 - 06/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Carbon Monoxide Poisoning:

1.	OxygenIBA 05/01/2014 - "His work on high altitude physiology, diving physiology, oxygen therapy, and carbon monoxide poisoning led to a sea change in clinical medicine and improved safety and reduced mortality and morbidity in many high risk situations. " 09/01/2011 - "Currently, the use of hyperbaric oxygen is a valid therapeutic for carbon monoxide poisoning management. " 01/01/2011 - "To examine randomised trials of the efficacy of hyperbaric oxygen (HBO) compared to normobaric oxygen (NBO) for the prevention of neurologic sequelae in patients with acute carbon monoxide poisoning. " 01/01/2010 - "Hyperbaric oxygen ameliorates delayed neuropsychiatric syndrome of carbon monoxide poisoning." 11/04/2015 - "A commentary on "The effectiveness of oxygen therapy in carbon monoxide poisoning is pressure- and time-dependent: A study on cultured astrocytes"."
2.	Carbon MonoxideIBA 01/01/2001 - "The different course of acute carbon monoxide poisoning in two young people exposed to the same Carbon monoxide source are reported in the study. " 01/01/1961 - "A study of the effect of protracted occupational exposure to carbon monoxide with special reference to the occurrence of so-called chronic carbon monoxide poisoning." 01/01/2016 - "Acute carbon monoxide poisoning was achieved by exposing the rats to carbon monoxide at 2,500 ppm for 40 minutes, followed by 3,000 ppm for 20 minutes. " 02/01/2015 - "Carbon monoxide intoxication is the most prevalent cause of death from carbon monoxide poisoning. " 01/01/2015 - "Results provide evidence that exposure to cautionary tales positively influences adoption of attitudes and intentions to purchase a carbon monoxide detector and talk about accidental carbon monoxide poisoning. "
3.	Charcoal (Charbon)IBA 03/01/2010 - "We conducted an exploratory controlled trial to examine the efficacy of restricting access to charcoal in preventing suicides from carbon monoxide poisoning by charcoal burning in Hong Kong. " 09/01/2014 - "Forensic aspects of carbon monoxide poisoning by charcoal burning in Denmark, 2008-2012: an autopsy based study." 02/01/2015 - "In the late 1990s, an epidemic rise in suicides by carbon monoxide poisoning from burning barbecue charcoal began in Hong Kong and Taiwan. " 01/01/2015 - "Many cases of carbon monoxide poisoning in Taiwan are due to burning charcoal. " 01/01/2015 - "Acute carbon monoxide poisoning due to charcoal is well reported worldwide, and increased use of charcoal in the restaurant industry raises concern for an increase in occupational health problems. "
4.	CarboxyhemoglobinIBA 01/01/2014 - "The fact that all the Paramedic Rescue Squads were equipped with medical triage sets and were able to conduct non-invasive measurements of carboxyhemoglobin made it possible to introduce effective procedures in the cases of suspected carbon monoxide poisoning and abandon costly and complicated organisational procedures when they proved to be unnecessary." 01/01/2014 - "Case of interval form of carbon monoxide poisoning without increased carboxyhemoglobin level diagnosed by characteristic MR spectroscopy findings." 03/01/2012 - "Symptoms of carbon monoxide poisoning do not correlate with the initial carboxyhemoglobin level." 01/01/2011 - "[Estimation of carbon monoxide poisonings frequency, based on carboxyhemoglobin determinations performed in Toxicology Laboratory in Krakow in years 2002-2010]." 06/01/2010 - "[Carboxyhemoglobin concentration in carbon monoxide poisoning. "
5.	SmokeIBA 01/01/2009 - "Carbon monoxide poisoning has been reported as a result of exposure to various sources of smoke, such as car exhaust fumes, home water heaters and tobacco smoke. " 11/01/1993 - "Carbon monoxide poisoning usually results from inhalation of exhaust fumes from motor vehicles, smoke from fires or fumes from faulty heating systems. " 07/01/1990 - "Carbon monoxide poisoning in smoke inhalation." 03/01/1990 - "Severe carbon monoxide poisoning with fatal levels of HbCO (greater than 50 percent) was found at the end of smoke inhalation. " 05/01/1989 - "We then audited the medical records of all patients treated during a four-year period with the diagnosis of carbon monoxide poisoning or smoke inhalation to determine the actual utilization of this therapeutic modality. "
6.	Protons (Proton)IBA 03/01/1996 - "Neither CT scan nor MRI adequately demonstrated the source of visual dysfunction; however, single proton emission tomography (SPECT) scanning in a patient with carbon monoxide poisoning and positron emission tomography (PET) scanning in a patient with post-hypoxic delayed encephalopathy were helpful in confirming the organic substrate of their visual impairment. " 09/28/1998 - "Clinical studies on three cases of the interval form of carbon monoxide poisoning: serial proton magnetic resonance spectroscopy as a prognostic predictor." 04/15/1995 - "Serial proton magnetic resonance spectroscopy in a patient with acute carbon monoxide poisoning." 01/01/1995 - "Serial proton magnetic resonance spectroscopy in a patient with the interval form of carbon monoxide poisoning."
7.	HydrogenIBA 08/01/2010 - "Hydrogen as a novel and effective treatment of acute carbon monoxide poisoning." 05/01/2013 - "Neuroprotective effect of hydrogen-rich saline in acute carbon monoxide poisoning." 01/01/2013 - "Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning." 08/01/2010 - "Based on the findings abovementioned, we hypothesize that hydrogen therapy may be an effective, simple, economic and novel strategy in the treatment of acute carbon monoxide poisoning." 12/01/2012 - "Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning."
8.	SootIBA 06/01/2000 - "Children extracted from a closed-space fire who had airway soot, singed facial hair/facial burns, or respiratory distress were defined as having smoke inhalation and carbon monoxide poisoning (CO/SI). " 01/01/1992 - "The postmortem findings of soot in the airway and elevated carbon monoxide in the blood of most of these victims [the carboxyhemoglobin (COHb) concentration was in one case less than 10%, in ten cases greater than or equal to 10 to 50%, and in seven cases greater than 50%] were helpful in determining that the individuals were not only alive at the time of the fire but also that a significant number died from smoke inhalation and carbon monoxide poisoning. "
9.	phenylmethylpyrazoloneIBA 05/01/2013 - "The free radical scavenger, edaravone, ameliorates delayed neuropsychological sequelae after acute carbon monoxide poisoning in rabbits." 12/01/2015 - "Effect of free radical scavenger, edaravone, for patients with carbon monoxide poisoning." 05/01/2013 - "Our present research demonstrates that edaravone could ameliorate DNS after acute carbon monoxide poisoning in rabbits. "
10.	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/01/2016 - "To test the hypothesis that hyperbaric oxygen therapy ameliorates delayed cognitive impairment after acute carbon monoxide poisoning by promoting neurogenesis through upregulating the brain-derived neurotrophic factor in the hippocampus. " 01/01/2016 - "Hyperbaric Oxygen Therapy Alleviates Carbon Monoxide Poisoning-Induced Delayed Memory Impairment by Preserving Brain-Derived Neurotrophic Factor-Dependent Hippocampal Neurogenesis." 01/01/2016 - "The early hyperbaric oxygen treatment may alleviate delayed memory impairment after acute carbon monoxide poisoning by preserving adult neurogenesis via an increase in hippocampal brain-derived neurotrophic factor content." 01/01/2016 - "Blockade of hippocampal brain-derived neurotrophic factor signaling with intracerebroventricular infusion of recombinant human TrkB-Fc chimera significantly blunted the protection by the hyperbaric oxygen on hippocampal neurogenesis; whereas intracerebroventricular infusion of brain-derived neurotrophic factor mimicked the action of hyperbaric oxygen and preserved hippocampal neurogenesis after acute carbon monoxide poisoning. " 01/01/2016 - "Rats were divided into five groups: (1) non-carbon monoxide-treated control, (2) acute carbon monoxide poisoning, (3) acute carbon monoxide poisoning followed by 7-day hyperbaric oxygen treatment, (4) carbon monoxide + hyperbaric oxygen with additional intracerebroventricular infusion of Fc fragment of tyrosine kinase receptor B protein (TrkB-Fc) chimera, and (5) acute carbon monoxide poisoning followed by intracerebroventricular infusion of brain-derived neurotrophic factor. "

Therapies and Procedures

1.	Hyperbaric Oxygenation 10/01/2013 - "Acupuncture treatment can effectively strengthen the efficacy of hyperbaric oxygen therapy in the treatment of delayed encephalopathy caused by carbon monoxide poisoning." 03/01/2013 - "[A 25-year study (1983-2008) of children's health outcomes after hyperbaric oxygen therapy for carbon monoxide poisoning in utero]." 07/01/2011 - "Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials." 03/01/2011 - "Hyperbaric oxygen therapy for acute domestic carbon monoxide poisoning: two randomized controlled trials." 12/01/1996 - "The object of this study was to determine the nature of carbon monoxide poisoning and to evaluate the effect of hyperbaric oxygen therapy for such patients. "
2.	Decompression 06/01/1999 - "Although it has been used successfully to treat decompression illness and arterial air embolism, its role in the treatment of carbon monoxide poisoning remains somewhat controversial. " 01/01/2014 - "Most discrepant ratings were in the indications of decompression illness (C, high), carbon monoxide poisoning (A, very low), and later presentations of idiopathic sudden hearing loss (A, very low). " 01/01/2000 - "Decompression illness, iatrogenic gas embolism, and carbon monoxide poisoning: the role of hyperbaric oxygen therapy."
3.	Ligation 01/01/1953 - "Vestibular symptoms in carbon monoxide poisoning after unilateral ligation of the common carotid artery; an experimental study in cats." 01/01/1969 - "[Animal experiments on the effect of carbon monoxide poisoning on the cerebral circulation impaired by carotid ligation]." 09/01/1973 - "[Experimental studies on carbon monoxide poisoning--histopathological examinations of cat's white and gray matters with lesions induced by unilateral common carotid ligation followed by carbon monoxide inhalation (author's trransl)]."
4.	Resuscitation 06/01/1973 - "[Resuscitation treatment of patients with carbon monoxide poisoning]." 04/01/1973 - "[Resuscitation measures in carbon monoxide poisoning]." 11/01/1970 - "[Resuscitation measures in the treatment of acute carbon monoxide poisoning]." 11/01/1968 - "[Resuscitation of patients in severe forms of carbon monoxide poisoning]." 09/02/1959 - "Resuscitation of dogs from severe acute carbon monoxide poisoning."
5.	Artificial Respiration (Mechanical Ventilation) 02/01/2015 - "Predicting duration of mechanical ventilation in patients with carbon monoxide poisoning: a retrospective study." 03/01/1968 - "Treatment of carbon monoxide poisoning by mechanical ventilation: case report." 12/01/2009 - "Assessment of myocardial injury in the emergency department independently predicts the short-term poor outcome in patients with severe carbon monoxide poisoning receiving mechanical ventilation and hyperbaric oxygen therapy." 06/01/2008 - "A 4-year-old boy was found unconscious due to carbon monoxide poisoning, and required cardiopulmonary resuscitation, mechanical ventilation and inotropic support. " 05/01/2000 - "This paper reports the outcome after carbon monoxide poisoning in 31 consecutive patients treated with mechanical ventilation and hyperbaric oxygen therapy, compared with another study of mechanically ventilated patients treated with normobaric oxygen. "