Carbohydrates

A class of organic compounds composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n. The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES.

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Networked: 22023 relevant articles (837 outcomes, 2651 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Hu, Frank B: 50 articles (01/2022 - 02/2004)
2.	Astrup, Arne: 47 articles (01/2022 - 01/2002)
3.	Volek, Jeff S: 46 articles (03/2022 - 07/2002)
4.	Willett, Walter C: 44 articles (11/2022 - 03/2002)
5.	Noakes, Manny: 44 articles (12/2021 - 03/2002)
6.	Brown, Lindsay: 43 articles (10/2021 - 11/2010)
7.	Núñez, Julio: 33 articles (04/2022 - 06/2007)
8.	Westman, Eric C: 33 articles (12/2021 - 09/2003)
9.	Sanchis, Juan: 28 articles (04/2022 - 06/2007)
10.	Yancy, William S: 28 articles (01/2022 - 09/2003)

Related Diseases

1.	Weight Loss (Weight Reduction) 01/01/2007 - "In this Review we discuss the current evidence on the efficacy of low-fat, low-carbohydrate and Mediterranean dietary patterns for weight loss, their potential mechanisms of action and important clinical considerations." 04/01/2005 - "The very low-carbohydrate dieters had a significantly greater decrease in LogSAA (P = 0.04), but their weight loss also was significantly greater (-7.6 +/- 3.2 vs. -4.3 +/- 3.5 kg, P < 0.01). " 09/01/2022 - "While there is a strong physiologic rationale for either carbohydrate restriction or fat restriction to achieve a calorie deficit needed for weight loss, evidence from randomized controlled trials suggest either type of diet is effective for weight loss. " 12/01/2015 - "In weight loss trials, low-carbohydrate interventions led to significantly greater weight loss than did low-fat interventions (18 comparisons; WMD 1·15 kg [95% CI 0·52 to 1·79]; I(2)=10%). " 04/01/2007 - "This study investigated whether the outcomes of the Weight Watchers POINTS Weight-Loss System could be improved by encouraging dieters to select low GI, high-carbohydrate foods. "
2.	Insulin Resistance 07/01/2016 - "In comparison to carbohydrate, SFA, or MUFA, most consistent favourable effects were seen with PUFA, which was linked to improved glycaemia, insulin resistance, and insulin secretion capacity." 02/01/1997 - "Recent studies have shown that subjects on an ad-lib low fat, high carbohydrate diet lose weight and, therefore, may have even greater improvement in the metabolic disturbances of the insulin resistance syndrome." 05/01/2022 - "It is proposed that a low-carbohydrate, high-fat (LCHF) diet positively ameliorates the MetS and reverses insulin resistance. " 01/01/2015 - "Further, insulin sensitivity was significantly improved in fasted female rats from carbohydrate-fed mothers. " 12/17/2011 - "Changes in the composition of the gut microbiota and/or markers of colonic carbohydrate fermentation did not contribute explaining the observed early onset and significant improvement of whole-body insulin sensitivity with the here investigated HCF-diet. "
3.	Type 2 Diabetes Mellitus (MODY) 10/01/2008 - "These results support the view that the quantity and quality of carbohydrate and fat may play important roles in the management of patients with type 2 diabetes mellitus and could result in improved beta-cell function over the long term." 10/03/2020 - "Alow carbohydrate diet (LCD) is more beneficial for the glycometabolism in type 2 diabetes (T2DM) and may be effective in reducing depression. " 01/01/2018 - "Here, we show that the combination significantly improved endothelial function and that carbohydrate restriction alone reduced circulating endothelial microparticles in individuals with type 2 diabetes. " 06/01/2011 - "A small rice bowl based meal plan was effective for the reduction of energy intake and control of marcronutrient intake in Korean obese men with type 2 diabetes consuming a high carbohydrate diet." 01/01/2021 - "Higher intake of microbiota-accessible carbohydrates and improved cardiometabolic risk factors: a meta-analysis and umbrella review of dietary management in patients with type 2 diabetes."
4.	Neoplasms (Cancer) 10/01/2014 - "In contrast, Sd(a) carbohydrate is abundantly detected in the normal gastrointestinal mucosa but dramatically reduced or lost in cancer tissues. " 01/01/2001 - "Recently, transfection of genes encoding various glysosyltransferases gene in sense and antisense orientation helped to bring direct evidence that changes in cell surface carbohydrates are important for the metastatic behavior of tumor cells. " 01/01/2021 - "Low-carbohydrate high-fat diets (LCHFDs) are thought to be beneficial for metabolic support in patients with advanced cancer. " 04/01/2021 - "This review article focuses on the insights of advances in the development of carbohydrate-based magnetic nanocomposites for safe and effective cancer treatment. " 06/10/2010 - "The results demonstrate the potential for using a carbohydrate recognition-based approach for efficiently targeting B cells in vivo that can offer improved treatment options for patients with B-cell malignancies."
5.	Body Weight (Weight, Body) 01/12/2022 - "APE potentially ameliorates high simple carbohydrate diet-induced body weight gain by mechanisms related to gut microbiota regulation and appetite inhibition." 09/01/2019 - "The feed intake of piglets was significantly increased by dietary high carbohydrate ratio (9:1) (p < 0.01); however, this did not result in improved body weight gain (p > 0.05). " 09/01/2005 - "Key PointsAthletes with disordered eating were more likely to report restricting their intake of carbohydrate and fat and using supplements to control their weight than asymptomatic athletesAmong female athletes, those with disordered eating wanted to lose a greater percentage of their current body weight than did asymptomatic athletesDisordered eating was not associated with greater frequencies of inadequate micronutrient intake in either genderAthletes with disordered eating may be at significantly greater risk for nutritional inadequacies than athletes who are asymptomatic due to macronutrient restriction and greater alcohol consumption. " 04/01/1994 - "These fat-preferring rats exhibited significantly greater body weight gain compared with rats preferring carbohydrate.(ABSTRACT TRUNCATED AT 250 WORDS)" 11/01/1995 - "However, in obese individuals or those concerned with body weight, fat in the yogurts was less effective in reducing subsequent food intake than carbohydrate. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Antigens
3.	Glucose (Dextrose)
4.	Insulin (Novolin)
5.	Lipids
6.	Carcinoembryonic Antigen
7.	Triglycerides (Triacylglycerol)
8.	Enzymes
9.	Carbohydrates
10.	Blood Glucose (Blood Sugar)

Related Therapies and Procedures

1.	Ketogenic Diet
2.	Therapeutics
3.	Glycemic Control
4.	Fat-Restricted Diet (Diet, Fat Restricted)
5.	Carbohydrate-Restricted Diet (Low Carbohydrate Diet)