HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Carbimazole

Subscribe to New Research on Carbimazole

An imidazole antithyroid agent. Carbimazole is metabolized to METHIMAZOLE, which is responsible for the antithyroid activity.

Also Known As:

Carbimazole Henning; Henning Berlin Brand of Carbimazole; Herbrand Brand of Carbimazole; Neo Tomizol; Neo-Mercazole; Neo-Thyreostat; Neomercazole; Roche Brand of Carbimazole; Sanofi Synthelabo Brand of Carbimazole; Tarbis Brand of Carbimazole; 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester

Networked: 425 relevant articles (30 outcomes, 29 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Azoles: 413
    - Imidazoles: 107
      - Carbimazole: 425

Experts

1.	Laurberg, Peter: 7 articles (11/2015 - 11/2013)
2.	Andersen, Stine Linding: 5 articles (11/2015 - 11/2013)
3.	Basu, Ansu: 2 articles (09/2015 - 07/2004)
4.	Chowdhury, Subhankar: 2 articles (11/2014 - 06/2008)
5.	Olsen, Jørn: 2 articles (10/2014 - 11/2013)
6.	Wu, Chun Sen: 2 articles (10/2014 - 11/2013)
7.	Humar, Matjaz: 2 articles (12/2013 - 03/2009)
8.	Heimrich, Bernd: 2 articles (12/2013 - 03/2009)
9.	Kek, Peng Chin: 2 articles (07/2013 - 11/2011)
10.	Taylor, Peter N: 2 articles (10/2012 - 01/2009)

Related Diseases

1.	Graves Disease (Basedow Disease) 06/01/1983 - "Carbimazole 30 mg once daily is a convenient and effective treatment for hyperthyroid Graves' disease. " 09/01/2014 - "To analyze the efficacy of low dose radioiodine therapy (5 mCi) in treatment of naive patients of Graves' disease in comparison to that in which it was already primed with an antithyroid drug, carbimazole. " 01/01/2013 - "Graves disease remained in remission after carbimazole withdrawal. " 01/01/2007 - "Carbimazole leads to remission in 61% of cases of Graves disease. " 05/01/1998 - "TSH suppression combined with carbimazole for Graves' disease: effect on remission and relapse rates."
2.	Hyperthyroidism 07/01/2006 - "The results of this study indicate that twice daily administration of carbimazole ointment to the inner pinna of the ear is an effective treatment for hyperthyroidism in cats. " 01/01/2005 - "We conclude that carbimazole therapy is effective in treating nonautoimmune hyperthyroidism. " 01/01/1994 - "Carbimazole treatment was effective in controlling hyperthyroidism. " 06/01/2006 - "Carbimazole ameliorates hyperthyroidism but reduces radioiodine uptake and adversely affects the outcome of simultaneous radioiodine therapy. " 06/01/2012 - "We performed a prospective observational study in 20 adults (19 women) with acquired hyperthyroidism before and during carbimazole treatment. "
3.	Thyrotoxicosis 03/01/1993 - "Comparison of the efficacy of single and multiple regimens of carbimazole in the treatment of thyrotoxicosis." 03/01/1993 - "This study was undertaken to determine the effect of once, twice or thrice daily doses of carbimazole on thyroid function in patients with thyrotoxicosis. " 04/11/1984 - "Eleven patients had evidence of thyroid autonomy and the three patients with absent TRH responses each gave a past history of goitre or thyrotoxicosis; a trial of carbimazole treatment in these three was without clinical benefit. " 03/01/1959 - "Thyrotoxicosis with special reference to treatment with neomercazole; a study of 120 cases." 01/01/2013 - "The medical history included a diagnosis of thyrotoxicosis made 6 months previously that was being treated with carbimazole by her general practitioner. "
4.	Tremor (Tremors) 01/01/2014 - "During treatment with the antithyroid agent carbimazole, the parkinsonian tremor clearly improved within two weeks. " 01/01/1997 - "Tremor also improved during the 1st month of the study by 31% in the carbimazole + placebo group versus 59% in the carbimazole + propranolol group. " 10/01/1985 - "The effects of nadolol (or placebo) and carbimazole on thyrotoxic tremor were investigated in 18 thyrotoxic patients. " 01/01/1997 - "We evaluated the use of propranolol as an adjunct to carbimazole in the treatment of hyperthyroid tremor and tachycardia in a double-blind, cross-over and placebo-controlled study. " 10/01/1985 - "Both nadolol and carbimazole produced significant reductions in tremor power although nadolol did not cause any change in serum free tri-iodothyronine and free thyroxine concentrations. "
5.	Body Weight (Weight, Body) 08/01/1981 - "Male rats (200 g body weight) were either untreated or given carbimazole (0.1 g/100 mg) in their drinking water for up to 24 weeks. " 10/01/1978 - "Female rats (200 g body weight) were either untreated or given carbimazole (0.1 g/100 ml) in their drinking water for up to 12 weeks. " 07/28/1990 - "The efficacy of treatment with TSH-suppressive doses of L-thyroxine (T4, 2.5 micrograms/kg body weight daily) either alone or combined with carbimazole (CBZ, 40 mg daily) was studied in 78 patients with sporadic non-toxic goitre in a prospective placebo-controlled double-blind randomised clinical trial. " 08/01/1981 - "Thyroid proliferation, body weight, thyrotropin and thyroid hormones in chronic antithyroid (carbimazole) treatment in rats." 11/01/2006 - "The first four groups were fed a control diet and in addition were given respectively 1% carboxymethyl cellulose (CMC); 10 mg/kg body weight carbimazole (CM); 10 mg CM + 40 mg/kg body weight piperine and 10 mg CM + 2 mg/kg body weight atorvastatin (ATV). "

Related Drugs and Biologics

1.	Iodine
2.	Iopanoic Acid (Telepaque)
3.	Methimazole (Thiamazole)
4.	Thyroxine (Levothyroxine)
5.	Propylthiouracil
6.	Propranolol (Inderal)
7.	Triiodothyronine (Liothyronine)
8.	Thyrotropin Receptors (Thyrotropin Receptor)
9.	Amiodarone (Amiodarona)
10.	potassium perchlorate

Related Therapies and Procedures

1.	Thyroidectomy
2.	Aftercare (After-Treatment)
3.	Cutaneous Administration
4.	Drug Therapy (Chemotherapy)
5.	Electric Countershock (Cardioversion)