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Caplan Syndrome

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A condition characterized by the presence of RHEUMATOID ARTHRITIS associated with a specific form of pneumoconiosis, often in coal miners and asbestos workers.

Also Known As:

Caplan's Syndrome; Caplan Syndromes; Caplans Syndrome

Networked: 12 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Pneumoconiosis
2.	Rheumatoid Arthritis
3.	Silicosis
4.	Systemic Scleroderma (Systemic Sclerosis)
5.	Nephritis

Experts

1.	Matsuzaki, Hidenori: 1 article (07/2012)
2.	Chen, Ying: 1 article (07/2012)
3.	Fujimoto, Wataru: 1 article (07/2012)
4.	Nishimura, Yasumitsu: 1 article (07/2012)
5.	Maeda, Megumi: 1 article (07/2012)
6.	Otsuki, Takemi: 1 article (07/2012)
7.	Takei-Kumagai, Naoko: 1 article (07/2012)
8.	Lee, Suni: 1 article (07/2012)
9.	Hayashi, Hiroaki: 1 article (07/2012)
10.	Kumagai, N: 1 article (01/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Caplan Syndrome:

1.	CoalIBA 12/01/1978 - "Pulmonary function in coal workers with Caplan's syndrome and non-rheumatoid complicated pneumosoniosis." 03/01/1962 - "[Caplan's syndrome in coal miners in the Ostrava-Karvina basin]." 06/01/1956 - "[Caplan's syndrome; first observation in the Lorraine coal fields]." 12/01/1978 - "This retrospective study compares the pulmonary function of 24 coal workers with Caplan's syndrome with that of 36 subjects with non-rheumatoid progressive massive fibrosis (PMF). " 03/01/1955 - "Pathological studies of modified pneumoconiosis in coal-miners with rheumatoid arthritis; Caplan's syndrome."
2.	Rheumatoid FactorIBA 05/01/1963 - "[CHROMATOGRAPHICAL STUDY OF THE RHEUMATOID FACTOR IN A CASE OF CAPLAN'S SYNDROME]."
3.	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/01/2011 - "Caplan syndrome complicated with rheumatoid arthritis (RA) is well known epidemiologically, and the incidence of complicated systemic sclerosis (SSc), systemic lupus erythematosus (SLE) and antineutrophilic cytoplasmic antibody (ANCA)-related nephritis have been reported frequently in silicosis patients. " 07/01/2012 - "Among the most typical factors involving these substances, it is well known that silica exposure causes not only pulmonary fibrosis known as silicosis, but also induces autoimmune diseases such as rheumatoid arthritis known as Caplan's syndrome, systemic sclerosis, systemic lupus erythematosus, and anti-neutrophil cytoplasmic autoantibody (ANCA)-related vasculitis/nephritis. "
4.	Silicon Dioxide (Sand)FDA LinkGeneric 09/01/2009 - "Although rare, rheumatoid pneumoconiosis, also known as Caplan's syndrome, can occur in workers exposed to silica, as well as in patients with silicosis, coal workers' pneumoconiosis or asbestosis. " 07/01/2012 - "Among the most typical factors involving these substances, it is well known that silica exposure causes not only pulmonary fibrosis known as silicosis, but also induces autoimmune diseases such as rheumatoid arthritis known as Caplan's syndrome, systemic sclerosis, systemic lupus erythematosus, and anti-neutrophil cytoplasmic autoantibody (ANCA)-related vasculitis/nephritis. "
5.	AsbestosIBA 12/01/1961 - "Rheumatoid pneumoconiosis (Caplan's syndrome) in an asbestos worker." 06/01/1979 - "Rheumatoid "pneumoconiosis" (Caplan's syndrome) in an asbestos worker: a 17 years' follow-up."
6.	AntigensIBA 09/10/1975 - "[Case of fulminant, HB antigen-associated hepatitis probably caused by blood transfusion during the clinical course of Caplan's syndrome]." 07/01/1983 - "HLA-A, B and DR antigens and properdin factor B allotypes in Caplan's syndrome."
7.	HLA-A Antigens (HLA-A)IBA 07/01/1983 - "HLA-A, B and DR antigens and properdin factor B allotypes in Caplan's syndrome."
8.	Complement Factor B (Factor B)IBA 07/01/1983 - "HLA-A, B and DR antigens and properdin factor B allotypes in Caplan's syndrome."
9.	A 17 (A-17)IBA 06/01/1979 - "Rheumatoid "pneumoconiosis" (Caplan's syndrome) in an asbestos worker: a 17 years' follow-up."

Therapies and Procedures

1.	Blood Transfusion (Blood Transfusions) 09/10/1975 - "[Case of fulminant, HB antigen-associated hepatitis probably caused by blood transfusion during the clinical course of Caplan's syndrome]."