Calcinosis

05/01/2014 - "This therapy may have a role in improving calcinosis, even if more studies are necessary to determine the safety and efficacy of this treatment in juvenile dermatomyositis-related calcinosis. "
10/01/2002 - "Aggressive management of juvenile dermatomyositis results in improved outcome and decreased incidence of calcinosis."
08/01/2012 - "No risk factors for calcinosis were identified in this study, although that complication was found in half of the patients with juvenile dermatomyositis studied."
08/01/2012 - "High frequency of calcinosis in juvenile dermatomyositis: a risk factor study."
01/01/2004 - "The objective of this study was to begin to relate the microstructure of calcinosis samples to clinical and laboratory characteristics of the juvenile dermatomyositis (JDM) patients. "

11/01/2015 - "Several pharmacologic therapies have been tried for calcinosis with variable results, but surgical excision of calcium deposits remains the mainstay of treatment."
01/01/2011 - "Imaging may help to distinguish metabolic calcification, such as primary tumoral calcinosis and the secondary one (associated with acquired disorders of calcium or phosphate regulation), from dystrophic calcification, which is associated to normal blood values of phosphate. "
11/01/2015 - "Our review identified observational studies that describe the frequency of calcinosis in SSc and associated clinical features, genetic studies in animal models of heritable disorders leading to calcium deposition, and case series and case reports describing new diagnostic approaches and therapeutic interventions. "
11/01/2005 - "The significant depression of serum calcium at the eastern LIS site correlates with excretory calcinosis, a calcium storage disease described from lobsters at this site, but contrasts with a seasonal elevation in serum calcium recorded in the temporal component of the study. "
11/01/2005 - "The findings of this study could explain why canine HAC may cause clinical signs such as calcinosis cutis that are associated with altered calcium metabolism."

04/01/1998 - "These results do not clearly indicate that diltiazem is effective in calcinosis associated with SSc. "
05/01/2010 - "We emphasize the fact that the presence of calcinosis cutis has not been described previously in patients with SS, and that diltiazem has partially improved our patient's cutaneous lesions."
06/01/1995 - "Diltiazem induces remission of calcinosis in scleroderma."
04/01/2014 - "Diltiazem is recommended by some authors as first-line approach in calcinosis cutis and is also the therapeutic principal referred by the largest number of available publications. "
04/01/2001 - "Treatment with diltiazem completely suppressed the development of calcinosis."

04/01/1990 - "Our findings support the suggestion that EHDP therapy can be an effective treatment for the inhibition of dystrophic arterial calcinosis."
10/01/2003 - "She was treated with 800 mg of etidronate 3 months after the etidronate therapy; periarticular calcinosis was diminished although arterial calcification was unchanged. "
03/01/1985 - "Calcinosis universalis treated with disodium etidronate."
05/01/1982 - "After 9 months of therapy with 12 mg/kg/Day of EHDP, a small decrease in the calcinosis was accompanied by a dramatic increase in joint mobility. "
05/01/1982 - "The use of disodium etidronate (EHDP) for the treatment of calcinosis is complicated by the threat of drug-induced inhibition of skeletal mineralization. "

08/01/2006 - "We suggest that probenecid is useful for the treatment of calcinosis of JDM."
01/01/1981 - "The authors call for controlled studies of probenecid treatment in calcinosis."
08/01/1988 - "Probenecid has also been utilized in the treatment of calcinosis."
01/22/1972 - "She was then treated with probenecid up to 2 g daily and her calcinosis lessened steadily over three years. "
01/22/1972 - "Treatment of calcinosis circumscripta with probenecid."

03/01/2007 - "To report the case of a woman with idiopathic sporadic tumoral calcinosis treated successfully with orally administered bisphosphonates. "
07/01/2014 - "To evaluate the efficacy of bisphosphonates for the management of tumoral calcinosis on optimized medical treatment. "
07/01/2015 - "Bisphosphonates were unable to either decelerate the progression of calcinosis or improve calcinosis in cases 5 and 6. In case 5, it took a relatively long time to control the disease activity despite the appropriate immunsuppressive treatment and she experienced multiple flares of active JDM. "
07/01/2014 - "Differential response of idiopathic sporadic tumoral calcinosis to bisphosphonates."
07/01/2014 - "When calcinosis is disseminated, it may require additional treatments (aluminium hydroxyde, bisphosphonates) possibly associated with surgery in case of large lesions. "

01/01/2010 - "In all three cases, calcinosis significantly decreased, and even totally cleared in patient 1. Total clearance of pre-existing calcinosis in JDM with pamidronate therapy has not been previously described with any of the aforementioned treatments. "
01/01/2010 - "We report three children with JDM who developed calcinosis and who received intravenous pamidronate with good results. "
01/01/2013 - "After receiving intravenous pamidronate, calcinosis lesions decreased and the patient regained full range of movement and quality of life. "
01/01/2014 - "Three administrations of intravenous pamidronate produced significant improvement in calcinosis, pain and function, leading to remission less than 1 year after induction of therapy. "
01/01/2010 - "Pamidronate (2mg/kg/year) produced dramatic improvement of pain and function within 2 months and calcinosis had completely resolved by 2 years. "

03/01/2003 - "Minocycline may be effective in the control of calcinosis in systemic sclerosis. "
03/01/2003 - "Patients with lcSSc who had cutaneous calcinosis causing pain or ulceration, or both, were prescribed minocycline 50 or 100 mg daily regularly in an open label manner between November 1994 and April 2000. "
03/01/2003 - "To evaluate the effect of minocycline as treatment for cutaneous calcinosis in limited cutaneous systemic sclerosis (lcSSc). "
03/01/2003 - "Treatment of cutaneous calcinosis in limited systemic sclerosis with minocycline."
06/01/2012 - "Pharmacologic agents used in the treatment of SSc-associated calcinosis include diltiazem, minocycline, warfarin, biphosphonates, and intravenous immunoglobulin. "

10/01/2004 - "Low dose warfarin may serve as an effective treatment for calcinosis in a selected group of patients who have small and relatively new onset calcinosis. "
07/01/1993 - "Since there seem to be few adverse effects, the use of warfarin in patients with calcinosis warrants further study."
07/01/1987 - "Four patients with calcinosis universalis were treated with 1 mg per day of warfarin for 18 months in a non-blind initial study. "
10/01/2004 - "Two of the patients, who had newly diagnosed, diffuse, and relatively small calcinotic lesions, responded to warfarin treatment, with complete resolution of the calcinosis. "
10/01/2004 - "Three patients with disseminated subcutaneous calcinosis were treated with low doses of warfarin for 1 year. "

08/01/2010 - "Although iatrogenic calcinosis cutis is generally a benign entity, the early recognition of the presentation of extravasation of calcium gluconate is important to avoid severe complications and possible medical malpractice disputes. "
11/01/2008 - "Iatrogenic calcinosis cutis following extravasation of calcium gluconate."
05/01/2008 - "Neonate with calcinosis cutis following extravasation of calcium gluconate."
12/01/2006 - "Calcinosis cutis in a newborn caused by minimal calcium gluconate extravasation."
09/01/2003 - "Calcinosis cutis following calcium gluconate extravasation."

01/01/2001 - "[Tumorous calcinosis in hemodialysis: anatomo-clinical study apropos of 3 cases]."
07/01/2014 - "Amelioration of uremic tumoral calcinosis with high-flux hemodialysis treatment."
06/01/2012 - "A 41-year-old male receiving hemodialysis for 10 years was referred to our hospital for multiple masses progressively growing in multiple joints and buttocks, which were diagnosed as giant tumoral calcinosis (TC) by radiographic findings. "
01/01/2012 - "Uremic tumoral calcinosis in a patient on hemodialysis."
10/01/2011 - "Massive, painful tumoral calcinosis in a long-term hemodialysis patient."

11/01/2012 - "Rapid resolution of uremic tumoral calcinosis after parathyroidectomy."
04/01/2009 - "The patient underwent parathyroidectomy and several weeks later, there was a dramatic regression of the tumoral calcinosis. "
07/01/1999 - "Tumoral calcinosis regression after subtotal parathyroidectomy: a case presentation and review of the literature."
01/01/1997 - "The case of a female patient with tumoral calcinosis disappearing after parathyroidectomy is presented."
01/01/1965 - "[DISCUSSION OF PARATHYROIDECTOMY IN RENAL CALCINOSIS]."

12/01/2008 - "Uremic tumoral calcinosis improved by kidney transplantation."
06/01/2012 - "Complete resolution of tumoral calcinosis after renal transplantation."
01/01/1991 - "In the second patient, fulminant necrotizing vascular calcinosis developed after successful renal transplantation. "
01/01/1991 - "Fulminant calcinosis in two patients after kidney transplantation."
06/01/1986 - "Pulmonary calcinosis after renal transplantation in pediatric patients."

09/01/2001 - "Tumour-like calcinosis causing reversible tetraparesis in a patient on continuous ambulatory peritoneal dialysis."
03/01/2001 - "Tumour-like calcinosis causing reversible tetraparesis in a patient on continuous ambulatory peritoneal dialysis."
01/01/1998 - "A 32-year-old male patient with a 2-year history of CAPD rapidly developed multiple metastatic calcification (tumoral calcinosis) adjacent to his fingers, elbows, and knee joints. "
01/01/1998 - "The present case suggests that combined therapy with hemodialysis and CAPD using a low-Ca dialysate, together with Ca-modulating agents, can be effective in ameliorating tumoral calcinosis in patients on CAPD."
01/01/1998 - "Successful treatment of tumoral calcinosis using continuous ambulatory peritoneal dialysis (CAPD) combined with hemodialysis is described. "

01/01/2012 - "After treatment failure, a biopsy specimen revealed calcium phosphate salt deposition in the soft tissue around the metacarpophalangeal joint, which was treated by excision of the tumoral calcinosis masses. "
10/01/1998 - "Regression of massive tumoral calcinosis of the ischium in a dialysis patient after treatment with reduced calcium dialysate and i.v. administration."
07/01/1986 - "Kidney histology of five infants who died during or immediately after treatment with adrenocorticotrophic hormone (ACTH) showed severe tubular and interstitial calcinosis. "
12/08/1978 - "The evolution of the mineral constituents of subcutaneous calcinosis induced in rats by topical calciphylaxis was studied by the method of quantitative chemical analysis, and after treatment with excited gases by electron spin resonance (ESR) analysis. "
04/01/1999 - "This report concerns two Filipino women, one with dermatomyositis, the other with undifferentiated connective tissue disease, who showed significant reduction of widespread calcinosis after treatment with diltiazem."