Butadienes

Four carbon unsaturated hydrocarbons containing two double bonds.

Also Known As:

Butadiene Derivatives; Derivative, Butadiene; Derivatives, Butadiene; Butadiene Derivative

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkenes: 265
      - Polyenes: 164
        Alkadienes: 1
        Butadienes: 3
        U 0126: 741
        1,3-butadiene: 355
        isoprene: 158
        styrene-butadiene rubber: 29
        hexachlorobutadiene: 15
        polybutadiene: 14
        S-pentachlorobuta-1,3-dien-yl-cysteine: 9
        1,4-(bis-glutathion-S-yl)-1,2,3,4-tetrachloro-1,3-butadiene: 3
        ABS resin: 3
        diphenylbutadiene: 3
        N-acetyl-S-pentachloro-1,3-butadienylcysteine: 2
        S-(1,2,3,4,4-pentachloro-1,3-butadienyl)glutathione: 2
        1,3-butadiene diepoxide: 1
        1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene: 1
        2-((4-(4-methylamino)phenyl)-1,3-butadienyl)benzimidazole: 1
        JS 3: 1
        SC 53450: 1
        styrene-butadiene-styrene triblock copolymer: 1
        xanthoascin: 1
        (E)-1-(2,3,6-trimethylphenyl)buta-1,3-diene
        (E)-1-(3,4-dimethoxyphenyl) butadiene
        (E)-bis(benzoboratacyclobutylidene)
        (E,E)-1,4-bis(2,3,4-trimethoxyphenyl)buta-1,3-diene
        1,1,2,3,4-pentachloro-4-(1-methylethoxy)-1,3-butadiene
        1,4-(bis-cystein-S-yl)-1,2,3,4-tetrachloro-1,3-butadiene
        1,4-bis(2-naphthyl)-2,3-dinitro-1,3-butadiene
        1,4-bis(glutathion-S-yl)-1,2,3,4-tetrachlorobuta-1,3-diene
        1,4-di-(2-trifluoromethyl)phenyl-1,3-butadiene
        1,4-dilithio-1,3-butadiene
        1,4-diphenyl-1,4-bis(tolylmethylthio)-1,3-butadiene
        1,4-diphenylbut-2-ene-1,4-dione
        1,4-diphenylbutadiene
        1-(2-(3-indolyl)ethylamino)-4-nitro-1,3-butadiene
        1-(tert-butyldimethylsiloxy)-1,3-butadiene
        1-chloro-1,3-butadiene
        1-hydroxymethyl-4-phenylsulfonylbutadiene
        1-methoxy-1,3-bis(trimethylsilyloxy)-1,3-butadiene
        1-methoxy-3-trimethylsilyloxy-1,3-butadiene
        1-nitro-4-phenylbutadiene
        2,3-diisocyano-1-(4-methoxyphenyl)buta-1,3-diene
        2,3-diphenylbuta-1,3-diene
        2-amino-4-(4'-hydroxyphenyl)-1,1,3-tricyanobuta-1,3-diene
        2-fluoro-3-phenylthio-1,3-butadiene
        2-methoxy-1,3-butadiene
        2-phenyl-3-silyl-1,3-butadiene
        2-trifluoromethyl-3-phenylthio-1,3-butadiene
        3-methyl-1,2-butadiene
        4,4'-butylidenebis(6-t-butyl-m-cresol)
        4-carboxybenzyl trans-1,3-butadiene-1-carbamate
        A-B-A triblock copolymer
        acrylic acid-1,3-butadiene-styrene polymer
        alpha,omega-dithienylbutadiene
        alpha-1,4,4-tetraphenyl-1,3-butadiene
        benzo(1,2-4,5)dicyclobutadiene
        benzylpentachlorobuta-1,3-dienyl sulfide
        BMY 22089
        BU 4704
        butadiene-N-(acetoxyphenyl)maleimide
        caulerpenynol
        cordyformamide
        crispatenine
        dichlorobutadiene
        ethyl 2,3-butadienoate
        isoprene monoxide
        LDS-698
        Methyl 3-(3',5'-dimethoxyphenyl)-2-(1-(4-methylpiperazin-1-ylcarbamoyl)-2-phenylvinyl)-2-butenoate
        poly(1,2-butadiene-b-ethylene oxide)
        poly(butadiene)107-poly(L-lysine)27
        poly-(butadiene-b-ethylenoxide)
        polybutadiene-block-poly(methacrylic acid)-block-poly(2-(dimethylamino)ethyl methacrylate)
        polystyrene-block-polyisoprene
        tetrachloro- 1,3-butadiene
        xanthocillin X dimethyl ether
        xanthocillin X monomethyl ether
        xanthocillin Y 1
        xanthocillin Y 2
        xantocillin

Experts

1.	Chen, Xiangyang: 1 article (01/2020)
2.	Hao, Jiping: 1 article (01/2020)
3.	Houk, K N: 1 article (01/2020)
4.	Li, Yingzi: 1 article (01/2020)
5.	Lou, Liguang: 1 article (01/2020)
6.	Quan, Haitian: 1 article (01/2020)
7.	Song, Bichao: 1 article (01/2020)
8.	Wang, Lu: 1 article (01/2020)
9.	Xia, Yuanzhi: 1 article (01/2020)
10.	Xie, Peipei: 1 article (01/2020)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2017 - "The optimal butadiene derivative, 9a, exhibited IC50 values of 0.056-0.089μM for five human cancer cell lines. " 01/01/2020 - "Moreover, the polysubstituted butadienes as novel building blocks were unprecedentedly assembled into macrocycles, which efficiently inhibited the P-glycoprotein and dramatically reversed multidrug resistance in cancer cells by 190-fold." 01/01/2017 - "A series of new butadiene derivatives was synthesized and evaluated as tubulin polymerization inhibitors for the treatment of cancer. "
2.	Chromosome Aberrations (Chromosome Abnormalities) 06/17/2010 - "All of the tested polychlorinated butadienes induced chromosome aberrations. "

Related Drugs and Biologics

1.	Tubulin Modulators
2.	Member 1 Subfamily B ATP Binding Cassette Transporter