Bursitis (Adhesive Capsulitis)

Inflammation or irritation of a SYNOVIAL BURSA, the fibrous sac that acts as a cushion between moving structures of bones, muscles, tendons or skin.

Also Known As:

Adhesive Capsulitis; Adhesive Capsulitis of the Shoulder; Capsulitis; Shoulder Adhesive Capsulitis; Adhesive Capsulitides; Adhesive Capsulitides, Shoulder; Adhesive Capsulitis, Shoulder; Bursitides; Bursitides, Pes Anserine; Bursitis, Pes Anserine; Capsulitides; Capsulitides, Adhesive; Capsulitides, Shoulder Adhesive; Capsulitis, Shoulder Adhesive; Frozen Shoulders; Pes Anserine Bursitides; Shoulder Adhesive Capsulitides; Shoulder, Frozen; Capsulitis, Adhesive; Frozen Shoulder; Pes Anserine Bursitis

Networked: 1705 relevant articles (238 outcomes, 371 trials/studies)

Relationship Network

Disease Context: Research Results

Musculoskeletal Diseases: 719
- Joint Diseases: 6509
  - Bursitis: 1705
    - Periarthritis: 346

Related Diseases

1.	Pain (Aches)
2.	Tendinopathy (Tendonitis)
3.	Shoulder Pain
4.	Bursitis (Adhesive Capsulitis)
5.	Rotator Cuff Injuries

Experts

1.	Cho, Chul-Hyun: 14 articles (05/2022 - 05/2013)
2.	Kim, Du Hwan: 9 articles (01/2022 - 05/2016)
3.	Murrell, George A C: 9 articles (02/2020 - 09/2005)
4.	Hagiwara, Yoshihiro: 8 articles (01/2021 - 05/2015)
5.	Itoi, Eiji: 8 articles (01/2021 - 03/2009)
6.	Ando, Akira: 7 articles (01/2021 - 05/2015)
7.	Koide, Masashi: 7 articles (01/2021 - 01/2016)
8.	Charalambous, Charalambos P: 6 articles (12/2021 - 01/2016)
9.	Buchbinder, Rachelle: 6 articles (01/2021 - 11/2007)
10.	Kanazawa, Kenji: 6 articles (01/2021 - 01/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bursitis:

1.	Adrenal Cortex Hormones (Corticosteroids)IBA 01/01/2018 - "Corticosteroid injection is a common treatment for frozen shoulder, but controversy still exists regarding the injection site with the best outcome. " 10/01/2011 - "A good outcome follows an MUA and injection of corticosteroid and local anaesthetic in patients with primary frozen shoulder, independent of the duration of the presenting symptoms, and this improvement is maintained in the long term." 10/01/2022 - "To determine whether multisite corticosteroid injection is more effective than a single injection in the nonsurgical treatment of frozen shoulder (FS) via a meta-analysis of randomized controlled trials. " 01/01/2022 - "Author Reply to "Regarding 'A Multisite Injection Is More Effective Than a Single Glenohumeral Injection of Corticosteroid in the Treatment of Primary Frozen Shoulder: A Randomized Controlled Trial'"." 01/01/2022 - "Regarding "A Multisite Injection Is More Effective Than a Single Glenohumeral Injection of Corticosteroid in the Treatment of Primary Frozen Shoulder: A Randomized Controlled Trial"."
2.	SteroidsIBA 01/01/2017 - "The three-site approach to steroid instillation in frozen shoulder is a safe method and provides early recovery and better improvement in shoulder function with less relapses." 12/01/1998 - "To demonstrate the therapeutic value of subacromial bursography (with a steroid injection) in adhesive capsulitis of the shoulder inadequately improved by arthrographic glenohumeral distension with steroid injection. " 01/01/2017 - "With the understanding about the pathological changes taking place in frozen shoulder and the biomechanics involved, we wanted to evaluate the short- and long-term efficacy of steroid injection by a novel three-site (NTS) injection technique and compare it with the single-site injection (SSI). " 03/01/2023 - "In the present study we compared the efficacy of single intra-articular steroid injection vs hydrodilatation with intra-articular steroids for frozen shoulder (FS) in the frozen phase. " 11/09/2022 - "Effect of the Critical Shoulder Angle on the Efficacy of Ultrasound-Guided Steroid Injection for Subacromial Bursitis."
3.	Hyaluronic Acid (Hyaluronan)IBA 01/01/2015 - "Effectiveness of hyaluronic acid administration in treating adhesive capsulitis of the shoulder: a systematic review of randomized controlled trials." 12/27/2017 - "The use of hyaluronic acid in the treatment of shoulder capsulitis: a systematic review." 02/01/2013 - "Treatment effects of ultrasound-guided capsular distension with hyaluronic acid in adhesive capsulitis of the shoulder." 04/01/2011 - "Sodium hyaluronate injection into the glenohumeral joint is a safe, effective treatment in the management of adhesive capsulitis of the shoulder. " 04/01/2011 - "Sodium hyaluronate injection into the glenohumeral joint is a treatment option in the management of adhesive capsulitis of the shoulder. "
4.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/01/2011 - "The aim of this study was to evaluate the efficacy of supervised physiotherapy supplemented with non-steroidal antiinflammatory drugs (NSAIDs) for treating adhesive capsulitis. " 01/01/2011 - "Supervised physiotherapy supplemented with NSAIDs improves the ROM values in most of patients with adhesive capsulitis. " 01/01/1998 - "The patient was treated with oral non-steroidal anti-inflammatory agents for symptoms of subacromial bursitis. " 10/01/2023 - "This case suggests that physical therapy (PT), exercise, and sporadic non-steroidal anti-inflammatory drug (NSAID) use are effective for improving chronic degenerative changes, associated bursitis, and loss of function in patients who developed CP-induced gait complications in young adulthood. " 09/01/2004 - "Conservative treatment (physical therapy and NSAIDs) is a good long-term treatment regimen for idiopathic adhesive capsulitis."
5.	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 01/01/2021 - "This study aimed to compare the efficacy of hydrodilatation with triamcinolone acetonide via the posterior glenohumeral recess and the rotator cuff interval in patients with adhesive capsulitis. " 01/01/2023 - "To investigate the efficacy of hydrodilatation with 40 mg triamcinolone acetonide (TA) compared with the same procedure with 10 mg TA in patients with adhesive capsulitis (AC) of the shoulders. " 01/01/2022 - "The aim of this study was to evaluate the clinical effect of glenohumeral injection with triamcinolone acetonide for frozen shoulder and to identify the factors related to extent of range of motion (ROM) recovery. " 09/01/2020 - "This study aimed to evaluate the feasibility and effect of triamcinolone acetonide (TA) injection for lateral malleolar (LM) bursitis. " 01/01/2022 - "Between July 2015 and May 2020, a total of 305 patients with primary frozen shoulder (147 males, 158 females; mean age: 55.8±4.3 years; range, 52 to 73 years) who underwent intra-articular glenohumeral injection of triamcinolone acetonide were retrospectively analyzed. "
6.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/2010 - "Here we report the rare case of an adolescent with septic trochanteric bursitis (treated successfully with intravenous antibiotics), review the available literature on septic bursitis, illustrate the importance of prompt recognition and treatment of this condition in any age group, and describe the clinical presentation and the radiologic findings." 02/15/2017 - "For septic bursitis, antibiotics effective against Staphylococcus aureus are generally the initial treatment, with surgery reserved for bursitis not responsive to antibiotics or for recurrent cases. " 01/01/2022 - "Efficacy of empiric antibiotic management of septic olecranon bursitis without bursal aspiration in emergency department patients." 01/01/2022 - "Our findings suggest that empiric antibiotics without bursal aspiration may be a reasonable initial approach to ED management of select patients with suspected septic olecranon bursitis." 01/01/2022 - "Eighty-eight percent of ED patients with suspected septic olecranon bursitis treated with empiric antibiotics without aspiration had resolution without need for subsequent bursal aspiration, hospitalization, or surgery. "
7.	Capsules (Microcapsules)IBA 03/01/1994 - "Arthrographic distention of the constricted capsule appears to be an excellent therapeutic intervention for achieving rapid symptomatic relief from adhesive capsulitis." 01/01/2019 - "Scapular mobilization and manual posterior capsule interventions were effective in improving the acute joint range of motion in frozen shoulder patients." 07/01/2016 - "We obtained glenohumeral joint synovium/capsule specimens from 9 patients with idiopathic adhesive capsulitis who had not shown improvement in symptoms after 5 months of physiotherapy. " 01/01/2019 - "This study aimed to compare the superiority of scapular mobilization, manual capsule stretching, and the combination of these two techniques in the treatment of frozen shoulder patients to evaluate the acute effects of these techniques on shoulder movements. " 01/01/2019 - "Control and diseased fibroblasts were cultured for in vitro studies from capsule biopsies from instability and frozen shoulder surgeries, respectively. "
8.	Lidocaine (Xylocaine)FDA LinkGeneric 08/23/2022 - "Considering the potential chondrotoxic effects of lidocaine, this retrospective study aimed to examine whether ultrasound-guided hydrodilatation without concurrent lidocaine infusion can still provide comparable treatment benefits for patients with adhesive capsulitis (AC). " 08/23/2022 - "Management of Patients with Adhesive Capsulitis via Ultrasound-Guided Hydrodilatation without Concomitant Intra-Articular Lidocaine Infusion: A Single-Center Experience." 01/01/2015 - "Correction: Addition of lidocaine injection immediately before physiotherapy for frozen shoulder: a randomized controlled trial." 01/01/2015 - "Addition of lidocaine injection immediately before physiotherapy for frozen shoulder: a randomized controlled trial." 01/01/2015 - "The intraarticular injection of lidocaine immediately before a physiotherapy session might be superior to physiotherapy alone in the treatment of a frozen shoulder. "
9.	Analgesics (Analgesic Drugs)IBA 04/19/2018 - "Due to the delayed onset of analgesic effects low dose RT results in a significantly improved long-term efficacy in comparison to the results immediately after RT particularly in patients with calcaneodynia, achillodynia, bursitis trochanterica, and shoulder syndrome." 04/01/2023 - "Combining SSNB with exercise is more effective in treatment of primary adhesive capsulitis than exercise alone and reduces the use of analgesics. " 01/01/2019 - "Analgesic gas for rehabilitation of frozen shoulder: Protocol for a randomized controlled trial." 08/01/2017 - "A progressive decrease in analgesic use, concomitant to a significant and similar reduction of bursitis and calcifications, was observed in both groups. " 07/31/2020 - "Analgesic effect of extracorporeal shock-wave therapy for frozen shoulder: A randomized controlled trial protocol."
10.	Triamcinolone (Aristocort)FDA Link 12/01/2015 - "Between 2008 and 2011 30 patients with idiopathic frozen shoulder underwent MUA, 15 of them received an additional injection of triamcinolone and bupivacain. " 10/01/2015 - "To evaluate responsiveness, assessments were performed at baseline with 4-week intervals in 23 subjects with adhesive capsulitis who were administered triamcinolone injection into the glenohumeral joint. " 11/10/2014 - "Injection of triamcinolone had satisfactory effect on the bursitis in one patient which is in contrast to previous reports. " 04/01/2005 - "To assess the effectiveness of intra-articular triamcinolone injection and physiotherapy singly or combined in the treatment of adhesive capsulitis of the shoulder. " 04/01/2005 - "A randomized controlled trial of intra-articular triamcinolone and/or physiotherapy in shoulder capsulitis."

Therapies and Procedures

1.	Injections 01/01/2017 - "Therefore, at least two monthly PRP injections may be beneficial for treating patients with minor to moderate knee OA combined with supra-patellar bursitis." 09/01/2022 - "Some recent studies reported a better outcome using platelet-rich plasma (PRP) injections in frozen shoulder cases. " 01/01/2021 - "The goal of this study is to investigate whether platelet-rich plasma (PRP) injections are effective in the management of adhesive capsulitis of the shoulder (AC). " 11/01/2021 - "Comment on "efficacy of platelet-rich plasma injections in patients with adhesive capsulitis of the shoulder"." 01/01/2021 - "Comment on "efficacy of platelet-rich plasma injections in patients with adhesive capsulitis of the shoulder"."
2.	Physical Therapy Modalities (Physical Therapy Technique) 02/01/2012 - "Adhesive capsulitis (AC) is a common and disabling shoulder condition seen in physical therapy, and there is no clear consensus as to the best treatment approach. " 06/01/2000 - "The adhesive capsulitis of both hip and shoulder were treated successfully with physical therapy. " 01/01/2006 - "The integration of acupuncture and physical therapy to treat frozen shoulder leads to a better outcome than using only one method. " 01/01/2020 - "A recent meta-analysis found that physical therapy is as effective as intra-articular distension (IAD) and that an early distension could be the primary choice for treating frozen shoulder. " 01/01/2016 - "[Conclusion] The combination of physical therapy, exercise, and manual techniques is effective in treating frozen shoulder. "
3.	Joint Capsule Release 01/01/2018 - "Arthroscopic 360° capsular release in the lateral decubitus position for idiopathic adhesive capsulitis results in a significant early and lasting improvement in ROM, excellent functional outcomes, and low revision and complication rates. " 03/01/2017 - "An investigation of recalcitrant idiopathic adhesive capsulitis of the shoulder showed good outcomes with arthroscopic capsular release. " 05/01/2010 - "Arthroscopic capsular release significantly improved the range of motion and function in idiopathic and posttraumatic frozen shoulder." 03/01/2010 - "The results of arthroscopic capsular release for frozen shoulder in diabetic patients had less good results in terms of range of motion and Constant-Score. " 01/01/2009 - "We have shown an overall rapid significant improvement following arthroscopic capsular release for primary and secondary frozen shoulder. "
4.	Therapeutics 01/01/2016 - "Arthroscopic management is most effective in treating the stiff shoulder in the setting of adhesive capsulitis recalcitrant to nonoperative therapy or posttraumatic stiffness. " 07/01/2003 - "The hydroplasty procedure combined with a therapy program is a successful treatment for idiopathic frozen shoulder." 03/01/2018 - "Navicular bursotomy in combination with systemic and local antimicrobial therapies is an effective treatment for contaminated or septic navicular bursitis. " 11/01/2015 - "Comparison for efficacy of general exercises with and without mobilization therapy for the management of adhesive capsulitis of shoulder - An interventional study." 12/01/2019 - "Efficacy of Pharmacological Therapies for Adhesive Capsulitis of the Shoulder: A Systematic Review and Network Meta-analysis."
5.	Intra-Articular Injections 10/01/2010 - "Good results after fluoroscopic-guided intra-articular injections in the treatment of adhesive capsulitis of the shoulder." 03/01/2016 - "The aim of this prospective randomized study was to compare the efficacy of 3 injection methods, intra-articular injection, subacromial injection, and hydrodilatation (HD), in the treatment of primary frozen shoulder. " 12/01/2009 - "Randomized controlled trial for efficacy of intra-articular injection for adhesive capsulitis: ultrasonography-guided versus blind technique. " 12/01/2009 - "Randomized controlled trial for efficacy of intra-articular injection for adhesive capsulitis: ultrasonography-guided versus blind technique." 12/22/2022 - "Further studies are required to ascertain the efficacy and safety of the PRP intraarticular injection as a management alternative in adhesive capsulitis."