Chemical Burns (Chemical Burn)

12/01/2012 - "UCS eye drops are more effective in improving corneal wound healing and reducing corneal haze compared with PBS eye drops and AT in experimental chemical burns."
12/01/2012 - "To evaluate the effect of umbilical cord serum (UCS) eye drops on corneal wound healing and haze in a mouse model of ocular chemical burn and compare with that of peripheral blood serum (PBS) eye drops or artificial tears (AT). "
12/01/2012 - "Effects of umbilical cord serum eye drops in a mouse model of ocular chemical burn."
12/01/2014 - "Eye drops made from umbilical cord serum have been applied to treat various ocular surface diseases, including severe dry eye with or without Sjögren's syndrome, ocular complications in graft-versus-host disease, persistent epithelial defects, neurotrophic keratopathy, recurrent corneal erosions, ocular chemical burn, and surface problems after corneal refractive surgery. "
02/01/2011 - "In a double-blind prospective randomized controlled clinical study, 33 eyes of 32 patients with acute ocular chemical burns of grade III, IV, and V severity were randomized into three groups: umbilical cord serum (n = 12), autologous serum (n = 11), and artificial tears (0.5% HPMC+0.3% glycerin; n = 10). "

12/01/2010 - "Early treatment with bevacizumab seems to be clinically beneficial in the management of limbal injury such as chemical burn."
04/01/2009 - "Subconjunctival injection of bevacizumab (2.5 mg/0.1 ml) was performed after corneal chemical burn injury. "
01/01/2009 - "A chemical burn was induced in the mid-cornea of the right eye in 119 mice; 56 of them were untreated and 63 were bevacizumab-treated. "
01/01/2011 - "[Effect of subconjunctival bevacizumab on corneal neovascularization and reepithelization 25 days after chemical burn]."
02/01/2008 - "Patients with aggressive corneal neovascularisation not responding to conventional therapy were treated with bevacizumab (Avastin) eye drops (5x/day; 5 mg/ml) for 0.5 to 6 months (mean: 3.6 +/- 2; four patients with limbal stem cell deficiency [three due to chemical burns and one inherited] and one after perforating keratoplasty). "

05/01/2001 - "Efficacy of topical phenol decontamination strategies on severity of acute phenol chemical burns and dermal absorption: in vitro and in vivo studies in pig skin."
01/01/2011 - "In the treatment of patients with this special chemical burn, it is key scheme to block phenol absorption and promote elimination of already absorbed poison as early as possible. "
04/01/1993 - "The highest concentrations of TCA and phenol may cause full-thickness facial chemical burns and leave long-lasting scars. "
01/01/1993 - "The absence of serious toxicity and major chemical burns in this series does not eliminate concern with the corrosive and systemic risks of phenol poisoning."
11/01/2011 - "Ethanol is readily available and does not cause chemical burns on contact, but it is unclear whether ethanol can achieve similar local control rates as phenol for treating GCTs. "

05/01/2004 - "A case of successful delayed reconstruction using a collagen based dermal substitute of a chemical burn injury to the face caused by sulphuric acid."
09/01/2014 - "The aim of this study was to evaluate the safety and efficacy of very high-fluence collagen crosslinking (CXL) as a means of achieving increased corneal rigidity and reduced enzymatic digestion in the vehicle cornea of Boston keratoprosthesis (KPro) type 1. Eleven consecutive patients fitted with a KPro (5 with a previous repeat cornea graft failure, 4 with ocular cicatricial pemphigoid, and 2 with chemical burn) underwent donor vehicle cornea pretreatment with very high-fluence prophylactic CXL in a 2-step procedure. "
06/01/1992 - "Chronic corneal perforations were observed in infective keratitis, degenerative keratolysis, neurotrophic keratitis, chemical burns, dry eyes, collagen vascular diseases, and following cataract extraction. "

12/01/2009 - "To evaluate the efficacy of amniotic membrane extract (AME) for ocular chemical burns. "
12/01/2009 - "AME failed to close the epithelial defect in all eyes with chronic chemical burn coexisting diffuse limbal stem cell deficiency; however, the area of epithelial defect decreased to 58% (11.1%-68.2%) at final visit. "
12/01/2009 - "Consecutive 14 eyes of 11 patients with acute or chronic chemical burns, being recruited in one referral centre, received AME topically in combination with traditional treatment. "
12/01/2009 - "Although it is a preliminary and uncontrolled study, topical application of AME is effective in reducing inflammation, promoting reepithelization in the treatment of chemical burns, especially for mild to moderate acute cases."

01/01/1992 - "Our current conclusions are that (1) immune reactions are efficiently inhibited with constantly effective blood levels of cyclosporin A, which has enormously increased the rate of keratoplasty successful in these patients; (2) if drug blood levels fall too low due to noncompliance of the patient or to metabolic disturbances, immune reactions may occur, especially during the early postoperative months; (3) serious chronic surface problems, which are especially associated with chemical burns, atopic inflammation, and other chronic kerato-conjunctival diseases, are partly ameliorated but not completely eliminated (surface disorders are presently ranked as the number one cause of transplant failure, whereas immune reactions can be effectively suppressed by cyclosporin A); and (4) close medical follow-up has revealed no serious systemic complication of cyclosporin A prophylaxis over periods of up to 37 months. "
01/01/1987 - "[Use of cyclosporin A eyedrops in the treatment of severe chemical burns]."

06/01/2001 - "The mean age was 25 years and the male to female ratio was 3:1. Alkali drain cleaners were the major cause of chemical burns in the series and this was seen in 75% of the total study population. "
06/01/1986 - "[Value of an amphoteric isotonic solution in the early treatment of corneoconjunctival alkali chemical burns: experimental and histological study]."
02/01/2015 - "Late-onset peripheral ulcerative sclerokeratitis associated with alkali chemical burn."
12/01/2014 - "Late-onset peripheral ulcerative sclerokeratitis associated with alkali chemical burn."
12/01/2012 - "The chemical burns mainly involved young males with the relatively close time of onset, and acid and alkali were the main causative factors in the process of industrial production. "

08/01/2010 - "There were no signs of chemical burn in 52.9% of the group who applied Diphoterine first compared with 21.4% of the group who applied water first. "
01/01/2009 - "Diphoterine has more recently been used in hospitals for delayed management of chemical burns to the skin and eyes. "
08/01/2010 - "After implementation of Diphoterine the "first aid" injury rate for chemical burns fell 24.7% (95% CI 0.5–43.0%). "
03/31/2015 - "This is a retrospective review of the clinical use of Diphoterine(®) on chemical burns in an adult tertiary referral burn centre, often with a delay of several hours after the injury. "
03/31/2015 - "patients admitted with chemical burns within 24 hours of the incident with an abnormal wound pH or in pain, were treated with Diphoterine(®) spray. "

03/01/2014 - "White phosphorus is a common industrial and military compound, which can cause severe thermal and chemical burns beyond what would be predicted from body surface area alone. "
08/01/2004 - "In this study, we compare incidence, cause and outcome of chemical burn injury over time and review the management of white phosphorus injuries. "
08/01/2004 - "Over a 51-year period, we have treated 276 patients with chemical burn injury including 146 white phosphorus injuries. "
08/01/2004 - "Treatment of white phosphorus and other chemical burn injuries at one burn center over a 51-year period."
08/01/2001 - "Phosphorus burns are a rarely encountered chemical burn, typically occurring in battle, industrial accidents, or from fireworks. "

12/01/1995 - "In this paper, we describe the problems caused by chemical burns in this case (lye), the surgical treatment, and possible complications. "
01/01/1990 - "41 years following lye chemical burn]."
10/18/1963 - "[ON THE UNUSUAL OUTCOME OF A CHEMICAL BURN DUE TO LYE]."
11/01/2014 - "This study reports a unique case of a Marjolin ulcer in a patient who presented with periocular sebaceous cell carcinoma 16 years after a lye chemical burn. "
12/01/1995 - "The long-term complication of an anastomotic stenosis with a poststenotic diverticulum in the case of lye chemical burn of the esophagus at the age of 2 prompted us to present this very rare case, in which 35 years ago the defect was bridged with a section of colon. "

01/01/2012 - "It has been shown that amniotic membrane transplantation (AMT) is an effective treatment for severe chemical burns, but the phenotypes of cells that infiltrate the amniotic membrane and the clinical significance of these cellular infiltrations have not previously been reported. "
09/01/2001 - "A histopathological study to investigate the efficacy of conjunctival auto-transplantation on alkaline chemical burns of the ocular surface. "
05/01/2015 - "To compare the efficacy of umbilical cord serum (UCS) with amniotic membrane transplantation (AMT) in cases of acute ocular chemical burns. "
07/01/2014 - "The aim of this study was to compare the outcome of conjunctival limbal transplantation with and without the use of amniotic membrane (AM) transplantation for the treatment of limbal deficiency after chemical burns to the eyes. "
01/01/2010 - "This study evaluated the outcome of corneal surface reconstruction with conjunctival limbal autograft and amniotic membrane transplantation in two children with unilateral ocular chemical burn who underwent surgery. "

09/01/2014 - "Hard palate grafts were shown to be very useful in reconstruction of the upper eyelid for correction of entropium due to symblepharon and distichiasis following thermal and chemical burns. "
09/01/2002 - "In this study, MMP-2 and MMP-9 expression was analyzed by in situ zymography on rabbit corneal chemical burns with and without human amniotic membrane graft. "
04/01/2012 - "Long-term effectiveness of autologous cultured limbal stem cell grafts in patients with limbal stem cell deficiency due to chemical burns."
09/01/2010 - "Limbal allografting from related live donors is more effective to reconstruct the ocular surface of limbal stem cell deficiency secondary to ocular chemical burn than allolimbal cadaver transplant. "
06/01/2006 - "The indications for the PBIKP were chemical burns (11 cases); highly vascularized failed grafts (11 cases); severe dry eyes with total vascularized cornea (6 cases); miscellaneous (3 cases). "

06/01/2015 - "The purpose of this study is to investigate the efficacy of decontamination by immediate surgical debridement in the acute management of chemical burns as compared to conventional dilutional approaches by irrigation or wetting. "
07/01/2014 - "We present our attempts at debridement and the system in place to manage patients with complex chemical burns. "
03/01/2015 - "Although most chemical burns require only first response and wound care, some require the attention of a specialist for surgical debridement and, occasionally, skin coverage and reconstruction. "
03/01/1998 - "This study examined several treatment modalities for partial thickness chemical burns: surgical excision; laser ablation and chemical debridement with Debridase or trypsin-linked to gauze. "

07/01/2008 - "To evaluate the role of deep anterior lamellar keratoplasty (DALK) in acute ocular chemical burns. "
07/01/2008 - "Evaluation of therapeutic deep anterior lamellar keratoplasty in acute ocular chemical burns."
02/01/2000 - "Limbal stem cell deficiency was due to chemical burns in 4 patients, history of prior surgery extending to the limbus in 2 patients, chronic limbitis with dystichiasis in one patient and persistent corneal epithelial defect after keratoplasty in one case. "
01/01/1997 - "Currently the main indications for LK are "immediate" keratoplasty after chemical burns, and sclerokeratoplasty against recurrent pterygia. "
10/01/1975 - "In spite of disadvantages related to its size and weight, the pump seems to be of considerable value, especially following severe chemical burns and after keratoplasty or reconstruction of the lids and fornices in the severely dry eye."

01/01/1989 - "[Endoscopic laser therapy of chemical burns of the esophagus (clinico-morphologic studies)]."
01/01/1991 - "[Effectiveness of the treatment of chemical burns of the esophagus by local endoscopic laser therapy]."
11/01/1990 - "[The local treatment of chemical burns of the esophagus via an endoscope by means of laser therapy and adhesive application]."
01/01/2015 - "Rapidly developed squamous cell carcinoma after laser therapy used to treat chemical burn wound: a case report."
03/01/1998 - "This study examined several treatment modalities for partial thickness chemical burns: surgical excision; laser ablation and chemical debridement with Debridase or trypsin-linked to gauze. "