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Levobunolol (AKBeta)

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A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.

Also Known As:

AKBeta; Betagan; Bunolol; Akorn Brand of Levobunolol Hydrochloride; Allergan Brand of Levobunolol Hydrochloride; Apo-Levobunolol; Apotex Brand of Levobunolol Hydrochloride; Bunolol Hydrochloride; Ciba Vision Brand of Levobunolol Hydrochloride; Levobunolol Hydrochloride; Novo-Levobunolol; Novopharm Brand of Levobunolol Hydrochloride; PMS-Levobunolol; Pharm-Allergan Brand of Levobunolol Hydrochloride; Pharmascience Brand of Levobunolol Hydrochloride; Ratiopharm Brand of Levobunolol Hydrochloride; Ultracortenol; Vistagan; W-6412A; W-7000A; ratio-Levobunolol; Apo Levobunolol; ApoLevobunolol; Novo Levobunolol; NovoLevobunolol; PMS Levobunolol; PMSLevobunolol; Pharm Allergan Brand of Levobunolol Hydrochloride; W 6412A; W 7000A; W6412A; W7000A; ratio Levobunolol; 1(2H)-Naphthalenone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-, (S)-

Networked: 87 relevant articles (10 outcomes, 8 trials/studies)

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Drug Context: Research Results

Experts

1.	Garudadri, Chandrasekhar S: 1 article (01/2015)
2.	Senthil, Sirisha: 1 article (01/2015)
3.	Krishnamurthy, Rashmi: 1 article (01/2015)
4.	Lin, Lianjun: 1 article (01/2014)
5.	Wang, Yuchuan: 1 article (01/2014)
6.	Liu, Meilin: 1 article (01/2014)
7.	Chen, Yan: 1 article (01/2014)
8.	Meyer, David: 1 article (01/2013)
9.	Mohamed, Nabiel: 1 article (01/2013)
10.	Scardillo, Alessio: 1 article (01/2010)

Related Diseases

1.	Ocular Hypertension (Glaucoma, Suspect) 02/01/1983 - "A dose-response study of the effect of levobunolol on ocular hypertension." 01/01/2014 - "Levobunolol hydrochloride solution is an effective therapy for ocular hypertension, probably by reducing aqueous fluid production. " 01/01/1990 - "The corneal endothelium was examined in ten patients suffering from ocular hypertension before, during and after four months of topical levobunolol treatment. " 01/01/1987 - "We evaluated the acute effects of installation of 0.5% levobunolol on aqueous humor dynamics in a double-masked study in 18 patients with ocular hypertension. " 02/01/1983 - "A single drop of placebo or levobunolol (at concentrations of 0.03%, 0.3%, 0.6%, 1%, and 2%) was administered to one eye of each of 48 patients with ocular hypertension. "
2.	Open-Angle Glaucoma (Glaucoma, Open Angle) 01/01/1993 - "We treated both eyes of 38 African American patients who have stable open angle glaucoma with either levobunolol b.i.d. " 09/01/1982 - "Data from two short-term double-masked studies using 24 and 16 subjects suggest that topically applied levobunolol safely and effectively treats open-angle glaucoma and ocular hypertension. " 02/01/1988 - "The authors evaluated the efficacy of once-daily treatment with levobunolol in patients with primary open-angle glaucoma or ocular hypertension in an open-labeled, two-phase titration clinical trial. " 05/01/1992 - "Effects of a single instillation of levobunolol, a new nonselective beta-adrenoblocker, in normal subjects and patients with various forms of glaucoma were under study, as were the effects of prolonged administration of this drug in patients with open-angle glaucoma. " 05/01/2008 - "27 eyes of 27 patients were consecutively randomized to receive preserved or unpreserved levobunolol; all patients had a recent diagnosis of primary open angle glaucoma (POAG) or ocular hypertension and were not previously treated with topical medications. "
3.	Glaucoma 09/15/1992 - "In a randomized, double-masked, placebo-controlled study, we evaluated the effect of levobunolol 0.5%, a nonselective beta-blocker, on intraocular pressure, volume amplitude, and ocular pulsatile flow in healthy individuals and patients with glaucoma. " 05/01/1992 - "[Results of the clinical study of a new adrenergic beta blocker levobunolol hydrochloride in healthy subjects and in patients with glaucoma]." 09/01/1985 - "The results of these studies indicate that levobunolol is an effective therapy for the long-term treatment of glaucoma." 11/01/2003 - "A 72-year-old man with long-standing bilateral glaucoma became refractory to levobunolol ophthalmic solution therapy after many years. " 10/01/1992 - "Vistagan is a new beta-blocker produced by Allergan that is used for treatment of glaucoma. "
4.	Contact Dermatitis (Eczema, Contact) 07/01/1999 - "Contact dermatitis from levobunolol eyedrops." 04/01/1997 - "Contact dermatitis due to levobunolol in eyedrops." 07/01/1995 - "Contact dermatitis from levobunolol and befunolol." 09/01/1989 - "A case is described in which, following local application of glaucoma eye drops containing Levobunolol, a recurring allergic contact eczema with periocular localisation occurred. " 12/01/2006 - "Contact dermatitis to levobunolol eyedrops superimposed on IgE-mediated rhinoconjunctivitis."
5.	Allergic Contact Dermatitis 07/01/2006 - "Allergic contact dermatitis due to levobunolol in an ophthalmic preparation." 01/01/2007 - "Allergic contact dermatitis due to levobunolol with cross-sensitivity to befunolol." 07/01/1995 - "Allergic contact dermatitis from levobunolol eyedrops." 08/01/1995 - "Allergic contact dermatitis due to timolol and levobunolol in eyedrops, with no cross-sensitivity to other ophthalmic beta-blockers."

Related Drugs and Biologics

1.	Timolol (Blocadren)
2.	Betaxolol (Kerlon)
3.	Ophthalmic Solutions (Eye Drops)
4.	Levobunolol (AKBeta)
5.	Metipranolol
6.	Pilocarpine (Ocusert)
7.	Isoproterenol (Isoprenaline)
8.	dipivefrin (Propine)
9.	Propranolol (Inderal)
10.	Carteolol (Carteolol Hydrochloride)

Related Therapies and Procedures

1.	Filtering Surgery
2.	Trabeculectomy (Trabeculoplasty)
3.	Topical Administration