Bovine Brucellosis (Bang's Disease)

01/04/2016 - "These results suggest that highly attenuated BA15ΔcydCΔcydD and BA15ΔcydCΔpurD mutants can be used effectively as potential live vaccine candidates against bovine brucellosis. "
05/21/2015 - "S19Δper mutant with intermediate rough phenotype displayed remarkable resemblance to S19 vaccine strain with improved properties of safety, immunogenicity and DIVA capability for control of bovine brucellosis. "
07/01/2022 - "This systematic review and meta-analysis aimed to recalculate the efficacy of Brucella abortus S19 and RB51 vaccine strains and discuss the main variables associated with controlled trials to evaluate bovine brucellosis vaccine efficacy (VE). "
01/01/2022 - "Efficacy of bovine brucellosis vaccines: Conceptions, challenges and meta-analysis. "
06/19/2006 - "With the goal of providing an additional tool for controlling bovine brucellosis in Brazil and evaluating the full calf dose in adult cattle, the efficacy of the rough Brucella abortus strain RB51 vaccine was tested in heifers. "

01/01/2005 - "Efficacy of several serological tests and antigens for diagnosis of bovine brucellosis in the presence of false-positive serological results due to Yersinia enterocolitica O:9."
12/15/2007 - "The present study was an investigation into the role of T lymphocytes in the killing of antigen-sensitized macrophages (M Phi) in bovine brucellosis. "
12/20/2002 - "Direct information from studies with immunized cattle supports the concepts of coordinate activation of uninfected Mø and killing of Brucella-infected Mø by antigen-specific T lymphocytes as major mechanisms of host defense in bovine brucellosis. "
03/01/2016 - "These results suggest that rMDH has the potential for use as a specific antigen in serological diagnosis for early detection of bovine brucellosis. "
01/01/2016 - "coli) as a diagnostic antigen in an Indirect ELISA (I-ELISA) for bovine brucellosis. "

06/01/1995 - "Improved competitive enzyme immunoassay for the diagnosis of bovine brucellosis."
12/01/1999 - "The purpose of this study was to evaluate the performance of the indirect enzyme immunoassay (IELISA) and the competitive enzyme immunoassay (CELISA) for the diagnosis of bovine brucellosis in comparison to conventional serological tests routinely used in Argentina. "
09/01/1998 - "Enzyme immunoassays for serological diagnosis of bovine brucellosis: A trial in Latin America."
09/01/1996 - "An indirect ELISA using a monoclonal anti-IgG1 enzyme conjugate for diagnosis of bovine brucellosis was evaluated. "
07/01/1990 - "Diagnosis of bovine brucellosis by enzyme immunoassay of milk."

07/01/2010 - "The diagnosis of bovine brucellosis mainly relies on serologic tests using smooth lipopolysaccharide (S-LPS) from B. "
05/21/2015 - "Development of an improved competitive ELISA based on a monoclonal antibody against lipopolysaccharide for the detection of bovine brucellosis."
09/01/2019 - "Using Brucella abortus Strain 19 (S19) to control bovine brucellosis is restricted due to induce antibodies to the O-side chain of the smooth lipopolysaccharide (LPS) which may be difficult to differentiate vaccinated and infected animals. "
11/01/2012 - "A rapid method for detection of the surface lipopolysaccharide antigen and the cells of the causative agent of bovine brucellosis was developed. "
11/01/2012 - "[Development of immunochromatographic test system for the rapid detection of lipopolysaccharide antigen and cells of causative agent of bovine brucellosis]."

01/01/1981 - "A simple method for the extraction of polysaccharide B from Brucella cells for use in the radial immunodiffusion test diagnosis of bovine brucellosis."
01/15/2009 - "The relative lack of the polysaccharide prevents it from inducing antibodies detectable by most of the serological tests used for the diagnosis of bovine brucellosis. "
12/01/1980 - "A radial immunodiffusion (RID) test employing a polysaccharide antigen (poly B) was compared with tests currently used in the diagnosis of bovine brucellosis. "
12/01/1980 - "Evaluation of a radial immunodiffusion test with polysaccharide B antigen for diagnosis of bovine brucellosis."
01/01/1955 - "[Diagnosis of bovine brucellosis by means of a skin test with a polysaccharide allergen from Brucella abortus. "

05/01/1989 - "Evaluation of three LPS-specific monoclonal antibodies for the immunodiagnosis of bovine brucellosis."
05/21/2015 - "Development of an improved competitive ELISA based on a monoclonal antibody against lipopolysaccharide for the detection of bovine brucellosis."
05/21/2015 - "One monoclonal antibody 3 F9, presented C epitope specificity, was used to develop a competitive ELISA for the serological detection of bovine brucellosis. "
01/01/1989 - "Bovine brucellosis: evaluation of field sera by a competitive and superimposable ELISA utilising a monoclonal antibody against Brucella abortus lipopolysaccharide."
01/01/1984 - "An enzyme immunoassay for bovine brucellosis using a monoclonal antibody specific for field strains of Brucella abortus."

05/01/2017 - "These results suggest that 2308ΔNodVΔNodW mutant is a potential live attenuated vaccine candidate and can be used effectively against bovine brucellosis."
06/01/2016 - "Brucella abortus RB51 is an attenuated vaccine strain that has been most frequently used for bovine brucellosis. "
11/01/2014 - "Both mutants should be evaluated further as a live attenuated vaccine against bovine brucellosis for their ability to stimulate a protective immune response."
11/01/2007 - "Brucella abortus strain RB51 is currently used as a live, attenuated vaccine against bovine brucellosis. "

11/01/1948 - "Successful streptomycin therapy in a case of Bang's disease."
09/01/1985 - "Efficacy of long-acting oxytetracycline alone or combined with streptomycin in the treatment of bovine brucellosis."
04/01/1950 - "[Treatment of Bang's disease with streptomycin and sulfadiazine]."

04/01/1951 - "Aureomycin in the treatment of bovine brucellosis."
02/01/1953 - "[Case of associated Malta fever with Bang's disease; aureomycin therapy]."
09/16/1950 - "[Aureomycin therapy of Bang's disease (successful therapy of brucellar osteomyelitis, strumitis and hepatitis)]."

03/16/2023 - "Novel multi-epitope vaccine against bovine brucellosis: approach from immunoinformatics to expression."
05/21/2015 - "One monoclonal antibody 3 F9, presented C epitope specificity, was used to develop a competitive ELISA for the serological detection of bovine brucellosis. "
04/01/2015 - "Improved serodiagnosis of bovine brucellosis by novel synthetic oligosaccharide antigens representing the capping m epitope elements of Brucella O-polysaccharide."

09/21/1951 - "[Therapy of Bang's disease]."
08/16/1951 - "[Former and modern therapy of Bang's disease]."
12/01/2020 - "Antibiotic therapy for bovine Brucellosis is expensive and may sometimes be ineffective as Brucella can become resistant. "
11/01/1948 - "Successful streptomycin therapy in a case of Bang's disease."
02/01/1953 - "[Case of associated Malta fever with Bang's disease; aureomycin therapy]."

06/01/2012 - "To determine whether rOmp2 has a potential benefit for use in the serodiagnosis of bovine brucellosis, rOmp28-based ELISA and latex bead agglutination test were performed. "

01/01/2021 - "Statically significant variation (P<0.05) in seroprevalence of bovine brucellosis was recorded among potential risk factors such as breed [P≤0.05; OR:8.905; CI:1.568-50.573], parity [P≤0.05; OR:0.017; CI:0.042-5.195], retained fetal membrane [P≤0.001; OR:0.018; CI:0.00-2.169], and abortion history [P≤0.001; OR:0.030; CI:0.004-0.212]. "
10/01/2018 - "The endemic circulation of bovine brucellosis in cattle herds has a markedly negative impact on economy, due to decreased fertility, increased abortion rates, reduced milk and meat production. "

09/01/2023 - "Even if 89 % of the farmers acknowledged being aware of the bovine brucellosis transmission to humans, only 46% of these farmers declared using protective gloves during calving or when handling abortions. "

09/01/2022 - "However, due to limitations associated with decreased specificity and a limited number of published articles on LAMP, the alternative use of PCR-based assays including those reported in literature is recommended while the use of LAMP for the detection of bovine brucellosis gains traction and should be evaluated more comprehensively in future."