Bronchogenic Cyst

A usually spherical cyst, arising as an embryonic out-pouching of the foregut or trachea. It is generally found in the mediastinum or lung and is usually asymptomatic unless it becomes infected.

Also Known As:

Networked: 167 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Bronchopulmonary Sequestration (Pulmonary Sequestration)
2.	Congenital Cystic Adenomatoid Malformation of Lung (Cystic Adenomatoid Malformation of Lung)
3.	Cysts
4.	Pneumothorax
5.	Neoplasms (Cancer)

Experts

1.	Crombleholme, Timothy M: 2 articles (01/2014 - 06/2008)
2.	Altinok, Tamer: 2 articles (01/2013 - 08/2002)
3.	Ballico, Maurizio: 1 article (01/2016)
4.	Marotta, Mario: 1 article (01/2016)
5.	Mimmi, Maria Chiara: 1 article (01/2016)
6.	Goruppi, Ilaria: 1 article (01/2016)
7.	Peiro, Jose Louis: 1 article (01/2016)
8.	Calcaterra, Valeria: 1 article (01/2016)
9.	Tonin, Elena: 1 article (01/2016)
10.	Costanzo, Federico: 1 article (01/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bronchogenic Cyst:

1.	Bleomycin (Blenoxane)FDA LinkGeneric 07/01/2010 - "CT-guided percutaneous treatment of bronchogenic cysts with large-needle aspiration and bleomycin sclerotherapy was safe and effective in this limited series. " 07/01/2010 - "The purpose of this study was to review our experience with computed tomography (CT)-guided percutaneous large-needle aspiration and bleomycin sclerotherapy of bronchogenic cysts in four patients. " 07/01/2010 - "Four patients with bronchogenic cysts at subcarinal (n = 1), paraspinal (n = 1), or intrapulmonary (n = 2) sites were treated at two medical centers with percutaneous transthoracic aspiration with a 17.5-gauge needle and sclerotherapy with use of bleomycin as the sclerosant agent. " 07/01/2010 - "CT-guided percutaneous large-needle aspiration and bleomycin sclerotherapy for bronchogenic cyst: report of four cases."
2.	Congenital lobar emphysemaIBA 01/01/2016 - "Bronchogenic cyst (BC), congenital lobar emphysema (CLE) and intrapulmonary sequestration (IPS), were analyzed with respect to a control sample. " 04/01/2012 - "Among the surgical specimens, there were 21 cases of CPAM, 11 cases of intralobar sequestration, 5 cases of congenital lobar emphysema and 17 cases of bronchogenic cyst. " 11/01/2008 - "Bronchogenic cyst: an uncommon cause of congenital lobar emphysema." 07/01/2008 - "The resected lesions included 21 congenital cystic adenomatoid malformations, 14 congenital lobar emphysema, four sequestrations and one bronchogenic cyst. " 05/01/2006 - "Congenital lobar emphysema and bronchogenic cysts occur rarely. "
3.	MucinsIBA 09/14/1973 - "[Purification and study of bronchogenic cysts mucins (author's transl)]." 11/01/2006 - "Histologically, both cysts were composed of ciliated respiratory-like epithelium with abundant mucin content, smooth muscle bundles and mature cartilage, compatible with the diagnosis of retroperitoneal bronchogenic cyst. "
4.	tebufenozide (Mimic)IBA 12/01/2013 - "Retroperitoneal bronchogenic cysts (BC) are rare clinical entities and may mimic an adrenal mass. " 11/01/2008 - "Although rare, cervical bronchogenic cysts are difficult to differentiate clinically from other cystic cervical masses because their location, radiologic characteristics, and evolution can mimic those of any other cervical mass. " 12/01/1987 - "Mere observation not only places these patients at serious risk, but also increases the possibility of missed diagnosis and delayed treatment of those lymphoproliferative malignancies involving mediastinal lymph nodes that can mimic a carinal bronchogenic cyst. " 05/01/2014 - "Cervical bronchogenic cysts mimic metastatic lymph nodes during thyroid cancer surgery." 01/01/2012 - "Bronchogenic cysts can in fact mimic hydatid cysts. "
5.	Calcium Carbonate (Limestone)FDA Link 02/01/2014 - "Bronchogenic cyst with milk of calcium." 09/01/2003 - "We report a rare case of retroperitoneal bronchogenic cyst showing characteristic imaging features of milk of calcium on plain abdominal radiography and computed tomography." 09/01/2003 - "Retroperitoneal bronchogenic cyst: a rare case showing the characteristic imaging feature of milk of calcium." 08/01/2002 - "Bronchogenic cyst with milk of calcium." 06/01/1987 - "[A case of milk of calcium fluid in a mediastinal bronchogenic cyst]."
6.	AntigensIBA 01/01/2002 - "The histological diagnosis was consistent with a bronchogenic cyst and carbohydrate antigen 19-9 could be immunohistochemically demonstrated within its epithelium." 01/01/2002 - "Subcarinal bronchogenic cyst with high carbohydrate antigen 19-9 production." 01/01/1998 - "Bronchogenic cyst with high carbohydrate antigen 19-9 in the cyst fluid and the serum." 11/01/1992 - "Antigen CA19.9 and bronchogenic cysts." 06/01/1990 - "This represents a rare case of bronchogenic cyst with abnormal increases in the respective carbohydrate antigens."
7.	CalciumIBA 07/01/1997 - "A 38-year-old man presented with a bronchogenic cyst which showed a high calcium content. " 07/01/1997 - "Calcium within a bronchogenic cyst with a fluid level." 08/01/1982 - "Radiographic evidence of calcium deposits was previously considered rare, but its demonstration with CT appears to be common in mediastinal bronchogenic cysts." 11/01/1965 - "Calcium in the fluid of mediastinal bronchogenic cyst: a new roentgenographic finding." 01/01/1988 - "Hyperlucent lung due to a calcium-containing bronchogenic cyst."
8.	CA-19-9 Antigen (CA 19-9 Antigen)IBA 05/15/1989 - "A case of bronchogenic cyst with high production of antigen CA 19-9." 01/01/2002 - "In a rare case of bronchogenic cyst with high carbohydrate antigen (CA) 19-9 production, a 57-year-old man with coughing and chest pain was diagnosed with a subcarinal mediastinal tumor. " 06/01/1989 - "Serum carbohydrate antigen (CA) 19-9 was present at high levels in pulmonary sequestration, mediastinal bronchogenic cysts, and mediastinal mature teratomas. "
9.	Pulmonary venous return anomalyIBA 03/01/2014 - "She was diagnosed with an infected bronchial cyst caused by congenital bronchial atresia with partial anomalous pulmonary venous return. " 09/01/2005 - "We describe a case of a 3-year-old child with an intrapericardial bronchogenic cyst arising from the pericardium overlying the pulmonary artery found incidentally at the time of elective repair of a sinus venosus atrial septal defect with partial anomalous pulmonary venous return. " 08/01/2015 - "Congenital lung malformations are a heterogeneous group of anomalies that involve the lungs and tracheobronchial tree (congenital airway pulmonary malformation, bronchial atresia, bronchogenic cyst, congenital lobar overinflation, pulmonary cyst, hamartoma, pulmonary isomerism and azygous lobe), vascular abnormalities (arteriovenous malformations, anomalous pulmonary venous return, pulmonary artery sling, interrupted pulmonary artery, pulmonary varix, pulmonary vein stenosis and pulmonary lymphangiectasia), or frequently both entities (pulmonary sequestration, pulmonary maldevelopment and scimitar syndrome). "
10.	Biological Tumor Markers (Tumor Markers)IBA 04/01/1998 - "We report on a case of a 43-old-male with a bronchogenic cyst in the distal esophagus, which was misdiagnosed as a malignant esophageal tumor based on preoperative imaging and high levels of the tumor markers CA 19-9 and CA 125." 02/01/2007 - "The common embryogenic origin of both respiratory and digestive apparatus can explain the increased levels of tumor markers such as CA 19-9 and carcinoembryonic antigen in bronchogenic cyst, intestinal duplication and pulmonary sequestration."

Therapies and Procedures

1.	Sclerotherapy 07/01/2010 - "CT-guided percutaneous treatment of bronchogenic cysts with large-needle aspiration and bleomycin sclerotherapy was safe and effective in this limited series. " 07/01/2010 - "The purpose of this study was to review our experience with computed tomography (CT)-guided percutaneous large-needle aspiration and bleomycin sclerotherapy of bronchogenic cysts in four patients. " 07/01/2010 - "Four patients with bronchogenic cysts at subcarinal (n = 1), paraspinal (n = 1), or intrapulmonary (n = 2) sites were treated at two medical centers with percutaneous transthoracic aspiration with a 17.5-gauge needle and sclerotherapy with use of bleomycin as the sclerosant agent. " 07/01/2010 - "CT-guided percutaneous large-needle aspiration and bleomycin sclerotherapy for bronchogenic cyst: report of four cases."
2.	Thoracotomy 03/01/2015 - "The cases with bronchogenic cysts resected by thoracotomy were confirmed by histological study. " 10/01/2015 - "The majority of the bronchogenic cysts mentioned in the literature were located mediastinally and were managed via open thoracotomy. " 03/01/2015 - "Thoracotomy is a safe procedure to resect bronchogenic cysts." 03/01/2015 - "Of the 12 cases with diagnosis of bronchogenic cysts surgically resected by thoracotomy, six were male and six female, with 50% located in lung parenchyma and 50% in mediastinum, one of the latter was para-oesophageal. " 08/01/2014 - "The conventional surgical approach for the removal of bronchogenic cyst in children is thoracotomy. "
3.	Sternotomy 11/01/2011 - "Following a complete excision via a median sternotomy, histopathologic examination identified the mass as a bronchogenic cyst with respiratory epithelial lining and cartilage elements. " 10/01/2008 - "Resection of intrapericardial bronchogenic cysts is possible, although extensive invasion of cardiac structures may necessitate the use of cardiopulmonary bypass through a sternotomy." 09/01/2014 - "[Direct ethanol injection by median sternotomy for a bronchogenic cyst compressing the pulmonary artery and the left atrium]."
4.	Thymectomy 02/01/2008 - "Histological examination after a thymectomy revealed a bronchogenic cyst in the thymus, and multiple LCH and small thymic cysts were also incidentally observed in the thymus. " 09/01/1993 - "We have reserved it for use during thymectomy in the management of new-onset myasthenia gravis and for the resection of benign thymic, pericardial, and bronchogenic cysts. " 04/01/2009 - "Weight ranged from 1.3 kg to 117 kg. The cases performed included aortopexy, congenital diaphragmatic repair, excision of a bronchogenic cyst, exploratory thoracoscopy, lung biopsy, resection extralobar sequestration, Nuss procedure, patent ductus arteriosus ligation, resection/biopsy of mediastinal lesions, resection of esophageal duplication, excision of parathyroid adenoma, hiatal hernia repair, esophagomyotomy, and thymectomy. "
5.	Thoracostomy 02/01/1992 - "Complications of successful thoracoscopy included suspected air embolus on establishing the initial pneumothorax and persistent air leak requiring tube thoracostomy after resection of a bronchogenic cyst. " 10/01/2010 - "A giant bronchogenic cyst in a 19-year-old woman presenting with pain and shortness of breath was mistaken for tension pneumothorax and initially treated with tube thoracostomy. " 11/01/1997 - "Pulmonary bronchogenic cysts with tracheobronchial communication may occasionally mimic tension pneumothorax leading to unnecessary thoracostomy. "