Bronchogenic Cyst

A usually spherical cyst, arising as an embryonic out-pouching of the foregut or trachea. It is generally found in the mediastinum or lung and is usually asymptomatic unless it becomes infected.

Also Known As:

Networked: 172 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Cysts
2.	Neurofibroma
3.	Pneumothorax
4.	Neoplasms (Cancer)
5.	Bronchopulmonary Sequestration (Pulmonary Sequestration)

Experts

1.	Coletta, Riccardo: 1 article (06/2022)
2.	Dell'Otto, Fabio: 1 article (06/2022)
3.	Gonfiotti, Alessandro: 1 article (06/2022)
4.	Lo Piccolo, Roberto: 1 article (06/2022)
5.	Morabito, Antonino: 1 article (06/2022)
6.	Ugolini, Sara: 1 article (06/2022)
7.	Voltolini, Luca: 1 article (06/2022)
8.	Briski, Lawrence: 1 article (05/2022)
9.	Huerta, Carlos Theodore: 1 article (05/2022)
10.	Kodia, Karishma: 1 article (05/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bronchogenic Cyst:

1.	Bleomycin (Blenoxane)FDA LinkGeneric 07/01/2010 - "CT-guided percutaneous treatment of bronchogenic cysts with large-needle aspiration and bleomycin sclerotherapy was safe and effective in this limited series. " 07/01/2010 - "The purpose of this study was to review our experience with computed tomography (CT)-guided percutaneous large-needle aspiration and bleomycin sclerotherapy of bronchogenic cysts in four patients. " 07/01/2010 - "CT-guided percutaneous large-needle aspiration and bleomycin sclerotherapy for bronchogenic cyst: report of four cases." 07/01/2010 - "Four patients with bronchogenic cysts at subcarinal (n = 1), paraspinal (n = 1), or intrapulmonary (n = 2) sites were treated at two medical centers with percutaneous transthoracic aspiration with a 17.5-gauge needle and sclerotherapy with use of bleomycin as the sclerosant agent. "
2.	SymportersIBA 04/01/2022 - "Respecting that unlike neurofibroma, immunohistochemistry studies have confirmed Na-I symporter expression in bronchogenic epithelium; our case highlights that, although rare, paravertebral bronchogenic cysts should be considered in differential diagnosis of radioiodine-avid paravertebral lesions." 07/08/2000 - "The pathophysiology of this iodine 131 uptake in a bronchogenic cyst is still unknown: the presence of NIS symporter or a protein which can organify iodine in the mucus cells of the cyst remains to be proven."
3.	MucinsIBA 09/14/1973 - "[Purification and study of bronchogenic cysts mucins (author's transl)]." 11/01/2006 - "Histologically, both cysts were composed of ciliated respiratory-like epithelium with abundant mucin content, smooth muscle bundles and mature cartilage, compatible with the diagnosis of retroperitoneal bronchogenic cyst. "
4.	CarbohydratesIBA 08/01/2022 - "We present an asymptomatic lady patient with a retroperitoneal cystic lesion that was submitted to endoscopic ultrasound-guided biopsies and intracystic fluid aspiration with histology excluding malignance despite intracystic fluid biochemical analysis that disclosed extremely high carbohydrate antigen 19-9. Definite diagnosis of bronchogenic cyst was only possible after complete surgical resection of the lesion. " 01/01/2002 - "The histological diagnosis was consistent with a bronchogenic cyst and carbohydrate antigen 19-9 could be immunohistochemically demonstrated within its epithelium." 01/01/2002 - "Subcarinal bronchogenic cyst with high carbohydrate antigen 19-9 production." 01/01/1998 - "Bronchogenic cyst with high carbohydrate antigen 19-9 in the cyst fluid and the serum." 06/01/1990 - "This represents a rare case of bronchogenic cyst with abnormal increases in the respective carbohydrate antigens."
5.	AntigensIBA 08/01/2022 - "Retroperitoneal Bronchogenic Cyst Mimicking a Pancreatic Cystic Lesion with Extremely High Level of Intralesional Fluid CA-19.9 Antigen: Benign in Disguise." 11/01/1992 - "Antigen CA19.9 and bronchogenic cysts." 08/01/2022 - "We present an asymptomatic lady patient with a retroperitoneal cystic lesion that was submitted to endoscopic ultrasound-guided biopsies and intracystic fluid aspiration with histology excluding malignance despite intracystic fluid biochemical analysis that disclosed extremely high carbohydrate antigen 19-9. Definite diagnosis of bronchogenic cyst was only possible after complete surgical resection of the lesion. " 01/01/2002 - "The histological diagnosis was consistent with a bronchogenic cyst and carbohydrate antigen 19-9 could be immunohistochemically demonstrated within its epithelium." 01/01/2002 - "Subcarinal bronchogenic cyst with high carbohydrate antigen 19-9 production."
6.	Calcium Carbonate (Limestone)FDA Link 02/01/2014 - "Bronchogenic cyst with milk of calcium." 09/01/2003 - "We report a rare case of retroperitoneal bronchogenic cyst showing characteristic imaging features of milk of calcium on plain abdominal radiography and computed tomography." 09/01/2003 - "Retroperitoneal bronchogenic cyst: a rare case showing the characteristic imaging feature of milk of calcium." 08/01/2002 - "Bronchogenic cyst with milk of calcium." 06/01/1987 - "[A case of milk of calcium fluid in a mediastinal bronchogenic cyst]."
7.	CalciumIBA 07/01/1997 - "A 38-year-old man presented with a bronchogenic cyst which showed a high calcium content. " 07/01/1997 - "Calcium within a bronchogenic cyst with a fluid level." 08/01/1982 - "Radiographic evidence of calcium deposits was previously considered rare, but its demonstration with CT appears to be common in mediastinal bronchogenic cysts." 11/01/1965 - "Calcium in the fluid of mediastinal bronchogenic cyst: a new roentgenographic finding." 01/01/1988 - "Hyperlucent lung due to a calcium-containing bronchogenic cyst."
8.	Anesthetics (Anesthetic Agents)IBA 07/01/2017 - "Anesthetic management for lobectomy of a 2-month-old infant with bronchogenic cyst: Case report along with review of literature." 10/01/2007 - "Perioperative risk associated with an unrecognized bronchogenic cyst: clinical significance and anesthetic management." 10/01/1994 - "Fluoroscopy as an aid to anesthetic management for bronchogenic cyst resection." 04/01/1993 - "Anesthetic management of the patient with a bronchogenic cyst: a review of 24 cases."
9.	CA-19-9 Antigen (CA 19-9 Antigen)IBA 05/15/1989 - "A case of bronchogenic cyst with high production of antigen CA 19-9." 01/01/2002 - "In a rare case of bronchogenic cyst with high carbohydrate antigen (CA) 19-9 production, a 57-year-old man with coughing and chest pain was diagnosed with a subcarinal mediastinal tumor. " 06/01/1989 - "Serum carbohydrate antigen (CA) 19-9 was present at high levels in pulmonary sequestration, mediastinal bronchogenic cysts, and mediastinal mature teratomas. "
10.	Carcinoembryonic AntigenIBA 01/01/2003 - "Bronchogenic cyst with high serum carcinoembryonic antigen." 08/26/2022 - "A unique intra-abdominal ectopic bronchogenic cyst with a mucinous neoplasm that was producing carcinoembryonic antigen (CEA), harboring a GNAS mutation, is reported. " 02/01/2007 - "The common embryogenic origin of both respiratory and digestive apparatus can explain the increased levels of tumor markers such as CA 19-9 and carcinoembryonic antigen in bronchogenic cyst, intestinal duplication and pulmonary sequestration."

Therapies and Procedures

1.	Sclerotherapy 07/01/2010 - "CT-guided percutaneous treatment of bronchogenic cysts with large-needle aspiration and bleomycin sclerotherapy was safe and effective in this limited series. " 07/01/2010 - "The purpose of this study was to review our experience with computed tomography (CT)-guided percutaneous large-needle aspiration and bleomycin sclerotherapy of bronchogenic cysts in four patients. " 05/01/2023 - "Percutaneous aspiration and absolute ethanol sclerotherapy in the treatment of symptomatic bronchogenic cyst." 01/01/2023 - "Endoscopic ultrasound-guided fenestration and lauromacrogol sclerotherapy for esophageal bronchogenic cyst." 07/01/2010 - "CT-guided percutaneous large-needle aspiration and bleomycin sclerotherapy for bronchogenic cyst: report of four cases."
2.	Therapeutics 08/01/2023 - "Bronchogenic cysts are uncommon mediastinal masses necessary for surgical therapy when discovered. " 12/01/2019 - "A complete excision is the most reliable therapy for bronchogenic cysts (BC) but is often accompanied by technical difficulties due to severe adhesions. " 01/01/2018 - "We present a unique case of an infected large bronchogenic cyst treated with endobronchial ultrasound drainage combined with conservative medical therapy. " 11/01/2007 - "Alcohol ablation therapy of an atypically located symptomatic bronchogenic cyst: a case report." 02/01/1982 - "Heterotopic pancreatic tissue in a bronchogenic cyst-diagnosis and therapy."
3.	Thoracotomy 10/05/2022 - "The objectives of our study are to evaluate our surgical experience of mediastinal bronchogenic cyst (MBC) and to determine the results of resection by video-assisted thoracic surgery (VATS) and posterolateral thoracotomy (PLT). " 03/01/2015 - "The cases with bronchogenic cysts resected by thoracotomy were confirmed by histological study. " 10/05/2022 - "Mediastinal Bronchogenic Cysts Resection in Adults: Results of Vats and Thoracotomy Procedures." 02/01/2018 - "The bronchogenic cyst was resected by thoracotomy and the patient was discharged 12 days after the operation without any complications over 5 years of follow-up." 09/01/2016 - "Video-assisted thoracic surgery compared with posterolateral thoracotomy for mediastinal bronchogenic cysts in adult patients."
4.	Segmental Mastectomy (Lumpectomy) 11/01/2017 - "A video-assisted thoracoscopic anterior basal segmentectomy was eventually performed, and an intrapulmonary bronchogenic cyst was the diagnosis based on histology." 11/01/1994 - "Surgical excision by segmentectomy or lobectomy for intrapulmonary lesions and simple excision for extralobar sequestrations and bronchogenic cysts are safe and have a low incidence of complications. " 06/01/2003 - "Thoracotomy and a segmentectomy of the apical segment of the lower lobe was performed, confirming the diagnosis of a ruptured bronchogenic cyst. " 03/01/2016 - "Operative procedures included thymectomy (9 ; 30%), lobectomy with nodes resection (11 ; 38%), segmentectomy (4 ; 14%), lymphadenectomy (3 ; 10%), Bronchogenic cyst (2, 5%) and posterior mediastinal mass resection (1 ; 3%). " 10/01/2015 - "We describe the case of a large gastric bronchogenic cyst in an asymptomatic 61-year-old woman who underwent an abdominal computerized tomography as part of a routine follow-up after lumpectomy due to breast cancer. "
5.	Esophagectomy 09/01/2023 - "[Esophagectomy for Bronchogenic Cyst within the Esophageal Muscle Layer with Dysphagia:Report of a Case]." 01/01/2018 - "Surgical treatment of an esophageal bronchogenic cyst with massive upper digestive tract hematoma without esophagectomy: a case report and the review of the literature." 08/01/2021 - "Paratracheal air cyst and bronchogenic cyst in patients with esophageal cancer who received thoracoscopic esophagectomy: A case series of three patients." 01/01/2018 - "Here we report a case of massive upper digestive tract hematoma and bronchogenic cyst mimicking aortic dissection that was safely removed without esophagectomy. " 11/14/2020 - "The first one is a case of anastomotic leak after esophagectomy for cancer complicated by pleuro-mediastinal abscess, while the second one is a leak of an esophageal suture, few days after resection of a bronchogenic cyst perforated into the esophageal lumen. "