Borrelia Infections

01/01/2021 - "Finally, qPCR and culture data show that both the OspA-OMV and the vaccine based on recombinant OspA with OMV as adjuvant provided significant, yet partial protection, against Borrelia infection. "
10/08/2018 - "The combination of all these proteins in a vaccine should allow improved protection against Borrelia infection."

01/01/2023 - "The results from this study suggest that there is an immunological protein pattern that can distinguish a present Borrelia infection from a previous exposure as well as anti-Borrelia antibody negative blood donors. "
05/01/2006 - "afzelii (one of the causative agents of Ixodes tick borne Borrelia infections) and the chromosomal gene coding protein P66 in 22 isolates, that in the natural focus located in the Middle Urals two different genetic subgroups (VS461 and NT28) of this genospecies simultaneously circulate. "
10/08/2018 - "The combination of all these proteins in a vaccine should allow improved protection against Borrelia infection."
01/01/2012 - "Factor H, in the case of Borrelia infection, is combined by CRASPs proteins of spirochetes, and thus prevents C3b molecules from contact with the pathogen, opsonisation and lysis of bacteria. "
11/01/2020 - "Outer surface protein A (OspA) is a pivotal protein in Borrelia infection, which is the etiological agent of Lyme disease. "

06/15/2008 - "Notably, this specific association was also observed in persons who did not recall Borrelia infection yet tested positive for anti-Borrelia antibodies (OR = 4.2 [2.0-8.9]). "
01/01/2008 - "The important and diverse roles of antibodies in the host response to Borrelia infections."
05/01/2005 - "The versatile roles of antibodies in Borrelia infections."
01/01/2004 - "The kits from Abbot and DAKO, that often predict clinically relevant Borrelia infection and do not detect antibodies in sera from patients without strong suspicion of Borrelia infection, were considered the most useful in the population studied. "
01/01/2001 - "Anti-Borrelia antibodies as well as Borrelia-specific T-cell responses were evident in 9 asymptomatic donors, strongly supporting a current or previous asymptomatic Borrelia infection."

10/01/2008 - "The specificity of an isolated Borrelia IgM titer in serum was 81%, and the positive predictive value for Borrelia infection only 50% in our material. "
01/01/2015 - "Borrelia infection was confirmed by the positivity of PCR and the presence of IgM antibodies. "
08/01/2011 - "The number of IgM- and/or IgG-positive ELISA results in the group of patients suspected of Borrelia infection ranged from 34 to 59%. "
01/31/1992 - "Serological tests demonstrated a recent Borrelia infection (rise of IgG antibody titre to 1:2048, IgM antibody titre to 1:128). "
12/23/1998 - "Specific anti-HGE IgG and/or IgM antibodies were more often discovered in cases of early Borrelia infection (stage I: 13.6%, stage II: 18.4%) than in patients with stage III disease (0%) or in seropositive but asymptomatic patients (6.8%). "

01/01/2016 - "Thus, 7.6% had IgG positivity, consistent with exposure to Borrelia infection. "
08/01/2011 - "The number of IgM- and/or IgG-positive ELISA results in the group of patients suspected of Borrelia infection ranged from 34 to 59%. "
01/31/1992 - "Serological tests demonstrated a recent Borrelia infection (rise of IgG antibody titre to 1:2048, IgM antibody titre to 1:128). "
11/01/1986 - "These two Borrelia infections, when left untreated, are now known to be capable of causing neurological problems, cardiac problems, relapses as much as ten years later, increased IgG/albumin ratio and increased lymphocytes. "
12/23/1998 - "Specific anti-HGE IgG and/or IgM antibodies were more often discovered in cases of early Borrelia infection (stage I: 13.6%, stage II: 18.4%) than in patients with stage III disease (0%) or in seropositive but asymptomatic patients (6.8%). "

12/12/2011 - "On suspicion of Borrelia infection the patient was prescribed penicillin treatment for 28 days with convincing effect. "
11/01/1989 - "Furthermore, two cases of erythema chronicum migrans, which is considered pathognomonic for Borrelia infection, were treated with penicillin perorally. "
02/01/1986 - "Investigations in 5 patients who developed neurologic symptoms after tick-borne borrelia infection revealed specific antibodies (IgM, IgG) against Borrelia burgdorferi in all sera, and all the patients recovered, one of them without treatment and the others under penicillin or tetracyclines. "

02/01/1986 - "Investigations in 5 patients who developed neurologic symptoms after tick-borne borrelia infection revealed specific antibodies (IgM, IgG) against Borrelia burgdorferi in all sera, and all the patients recovered, one of them without treatment and the others under penicillin or tetracyclines. "

03/01/2000 - "This suggested that amoxicillin and minocycline could be useful for the treatment of Chinese Borrelia infection."

03/01/2000 - "This suggested that amoxicillin and minocycline could be useful for the treatment of Chinese Borrelia infection."

11/01/2018 - "The study compares diagnostic parameters of different commercial serological kits based on three different antigen types and correlates test results with the status of the patient's Borrelia infection. "
04/18/2008 - "Population-based study of diagnostic assays for Borrelia infection: comparison of purified flagella antigen assay (Ideia, Dako Cytomation) and recombinant antigen assay (Liaison, DiaSorin)."
07/01/2015 - "Broad diversity of host responses of the white-footed mouse Peromyscus leucopus to Borrelia infection and antigens."
08/15/2007 - "A small part of these dogs also had antibodies directed against the IR6 (C6) antigen which indicates persistent active Borrelia infection. "
01/01/2007 - "From an initial screening of 244 patients with suspected Borrelia infection or disease, 4 informative recombinant antigens were selected: OspC (Borrelia afzelii), p41-1 (Borrelia garinii), p41-2 (B. "

08/01/1997 - "Early diagnosis and therapy of an acute Borrelia infection restrict the extent of the lesions and prevent ocular and general late manifestations. "
09/01/1994 - "Juxta-articular fibrotic nodules in Borrelia infection--ultrastructural details of therapy-induced regression."
12/01/2012 - "The article summarizes the latest knowledge about the etiology, epidemiology, pathogenesis, clinical signs, diagnostic procedures and therapy of erythema migrans (EM), a cutaneous form of Borrelia infection. "
11/14/2019 - "Potential Persistent Borrelia Infection and Response to Antibiotic Therapy; a Clinical Case Study and Review of Recent Literature."
04/14/2018 - "We present evidence of persistent Borrelia infection despite antibiotic therapy in patients with ongoing Lyme disease symptoms. "

04/01/2010 - "Because the clinical symptoms of Borrelia infection are widely variable, neuroborreliosis should be considered in patients with brainstem encephalitis refractory to conventional immunotherapies."

12/01/2003 - "Borrelia infection was observed in 95% of mice by the co-feeding method, in 92% of mice by xenodiagnosis, in 69% and in 68% of mice by cultivation of ear and back skin biopsies, respectively. "

12/01/1989 - "Since intrauterine transmission of Borrelia infection has been described, the inevitable question of whether this disease can also be transmitted as a result of blood transfusion becomes a major concern. "

11/01/2002 - "Our interpretation of the results is that the remaining neuropathy signs after treatment of ACA are neurological sequelae and not manifestations of persisting Borrelia infection."