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Boronic Acids

Subscribe to New Research on Boronic Acids

Inorganic or organic compounds that contain the basic structure RB(OH)2.

Also Known As:

Acids, Boronic

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Acids: 3146
  - Noncarboxylic Acids
    - Boronic Acids: 7
- Boron Compounds: 53
  - Boronic Acids: 7
Organic Chemicals: 58
- Boron Compounds: 53
  - Boronic Acids: 7

Experts

1.	Herscheid, J Koos D M: 1 article (10/2014)
2.	Orru, Romano V A: 1 article (10/2014)
3.	Sewing, Claudia: 1 article (10/2014)
4.	van der Born, Dion: 1 article (10/2014)
5.	Windhorst, Albert D: 1 article (10/2014)
6.	Vugts, Danielle J: 1 article (10/2014)
7.	Matteson, Donald S: 1 article (10/2013)
8.	Deb, Tushar B: 1 article (08/2012)
9.	Yenugonda, Venkata Mahidhar: 1 article (08/2012)
10.	Riggins, Rebecca B: 1 article (08/2012)

Related Diseases

1.	Neoplasms (Cancer) 08/01/1960 - "The localization of boronic acids in mouse neoplasm." 05/15/2009 - "Inhibition of the human cytosolic isoforms I and II and transmembrane, tumor-associated isoforms IX and XII with boronic acids." 07/01/2012 - "Our group, amongst others, have used boronic acids/esters as triggers for developing ROS-activated anticancer prodrugs that target cancer cells. " 05/15/2009 - "A series of aromatic, arylalkenyl- and arylalkyl boronic acids were assayed as inhibitors of four physiologically relevant carbonic anhydrase (CA, EC 4.2.1.1) isoforms, the cytosolic human (h) hCA I and II, and the transmembrane, tumor-associated hCA IX and XII. The best hCA I and II inhibitor was biphenyl boronic acid with, a K(I) of 3.7-4.5 microM, whereas the remaining derivatives showed inhibition constants in the range of 6.0-1560 microM for hCA I and of 6.0-1050 microM for hCA II, respectively. "
2.	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 10/18/2013 - "(α-Amidoalkyl)boronic acids include biochemically significant serine protease inhibitors, one of which is the clinically successful proteasome inhibitor bortezomib, used for treatment of multiple myeloma and mantle cell lymphoma. "
3.	Multiple Myeloma 10/18/2013 - "(α-Amidoalkyl)boronic acids include biochemically significant serine protease inhibitors, one of which is the clinically successful proteasome inhibitor bortezomib, used for treatment of multiple myeloma and mantle cell lymphoma. "
4.	Dehydration (Water Stress) 07/07/2011 - "The values of ΔH(298)(0) for boroxine formation via dehydration from the endo–exo conformers of these aliphatic boronic acids ranged from −2.9 for (H2N)3B3O3 to +12.2 kcal/mol for H3B3O3 at the MP2/aug-cc-pVTZ level in vacuo; for H3B3O3, the corresponding values in PCM/UFF implicit carbon tetrachloride and aqueous media were +11.2 and +9.8 kcal/mol, respectively. "
5.	Conversion Disorder (Astasia Abasia) 10/06/2014 - "In particular, the [(18)F]trifluoromethylation of boronic acids was found to outperform [(18)F]trifluoromethylation reactions of halogenated aryl precursors with regard to conversion, reaction conditions, and kinetics."

Related Drugs and Biologics

1.	Proteasome Endopeptidase Complex (Proteasome)
2.	Protein Isoforms (Isoforms)
3.	Serine Proteinase Inhibitors (Serine Protease Inhibitors)
4.	Prodrugs
5.	Esters
6.	Carbonic Anhydrases (Carbonic Anhydrase)
7.	Carbon Tetrachloride (Tetrachloromethane)
8.	bortezomib (Velcade)
9.	diphenyl (biphenyl)