Bloodletting

Puncture of a vein to draw blood for therapeutic purposes. Bloodletting therapy has been used in Talmudic and Indian medicine since the medieval time, and was still practiced widely in the 18th and 19th centuries. Its modern counterpart is PHLEBOTOMY.

Networked: 294 relevant articles (32 outcomes, 26 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Guo, Yi: 8 articles (08/2021 - 09/2012)
2.	Zhang, Sai: 7 articles (04/2021 - 09/2013)
3.	Cheng, Shi-Xiang: 4 articles (01/2020 - 09/2013)
4.	Tu, Yue: 4 articles (10/2019 - 09/2013)
5.	Fernández-Durán, Elena: 3 articles (07/2022 - 01/2021)
6.	Luque-Ramírez, Manuel: 3 articles (07/2022 - 01/2021)
7.	Ortiz-Flores, Andrés E: 3 articles (07/2022 - 01/2021)
8.	Quintero-Tobar, Alejandra: 3 articles (07/2022 - 01/2021)
9.	Álvarez-Blasco, Francisco: 3 articles (07/2022 - 01/2021)
10.	Zhou, Dan: 3 articles (08/2021 - 10/2019)

Related Diseases

1.	Chronic Urticaria 02/01/2019 - "Many trials have shown that bloodletting therapy is effective in treating chronic urticaria. " 01/01/2019 - "Many trials have reported that bloodletting therapy is effective when treating chronic urticaria. " 01/01/2019 - "Bloodletting therapy might be an effective and safe treatment for chronic urticaria, but the evidence is scarce. " 01/01/2020 - "To assess the efficacy of bloodletting therapy (acupoint pricking and cupping) in patients with chronic idiopathic urticaria (CIU) in a randomized, control, parallel-group trial. " 01/01/2020 - "Efficacy of Bloodletting Therapy in Patients with Chronic Idiopathic Urticaria: A Randomized Control Trial."
2.	Pain (Aches) 12/31/2022 - "Only the pain scores in the fire needling, bloodletting, and herbal medicine combination groups demonstrated significant improvement. " 01/01/2022 - "Our study aims to analyse the effect of using a vacutainer with cartoon characters on preschoolers' pain and fear levels during the bloodletting process. " 01/01/2020 - "This study has limited inclusion and exclusion criteria and a well-controlled intervention, and it will be the first randomized controlled trial to investigate pain of bloodletting device using the principle of "prestimulation neurodisturbance." This study provides insights into the underlying mechanisms of the pain-reducing effect of the developed bloodletting device and will lay the groundwork for further studies." 01/01/2020 - "In this study, we will investigate pain of bloodletting device during blood collection and will identify the safety of the device. " 01/01/2020 - "Pain assessment of a new bloodletting device: A study protocol for a randomized, controlled, double-blind, matched-paired clinical trial."
3.	Insulin Resistance 01/01/2021 - "Scheduled bloodletting does not improve insulin sensitivity in women with functional hyperandrogenism on COC." 03/01/2008 - "Bloodletting ameliorates insulin sensitivity and secretion in parallel to reducing liver iron in carriers of HFE gene mutations: response to Equitani et al." 01/01/2008 - "Bloodletting ameliorates insulin sensitivity and secretion in parallel to reducing liver iron in carriers of HFE gene mutations." 01/01/2021 - "Changes in insulin sensitivity index and frequency of prediabetes/diabetes, and percentage of women in whom bloodletting resulted in plasma hemoglobin <120 g/L and/or hematocrit <0.36. " 01/01/2017 - "In the subgroup of patients who lost weight, glycemia, homeostasis model of assessment of insulin resistance, serum ferritin, lipid profile, and liver function tests improved irrespective of bloodletting. "
4.	Iron Overload 01/01/2017 - "Metabolic and hepatic effects of bloodletting in dysmetabolic iron overload syndrome: A randomized controlled study in 274 patients." 06/30/1999 - "Today, however, bloodletting is being restored in modern medicine as the most effective method of treating the increasing frequent disorders caused by iron overload." 08/18/2022 - "Correction to: Iron Overload in Functional Hyperandrogenism: In a Randomized Trial, Bloodletting Does Not Improve Metabolic Outcomes." 01/01/2021 - "Iron Overload in Functional Hyperandrogenism: In a Randomized Trial, Bloodletting Does Not Improve Metabolic Outcomes." 06/01/2011 - "The objective was to determine whether periodic bloodletting could decrease triglyceride concentrations in subjects with HH and iron overload. "
5.	Pneumonia (Pneumonitis) 11/01/2006 - "Bernard praised the clinical researches of Pierre Louis aiming to assess the efficacy of bloodletting in the treatment of pneumonitis. " 01/01/2006 - "He eliminated bloodletting in pneumonia therapy. " 01/01/2021 - "The aim of this study was to explore, whether treatment with bloodletting at Shaoshang and Shangyang acupuncture points would affect therapy outcome and prognosis for severe community-acquired pneumonia (SCAP) in the elderly. " 10/01/2021 - "Benefits of bloodletting in pneumonia patients were contested during the 19th century. " 01/01/2021 - "Effect of Bloodletting at Shaoshang and Shangyang Acupuncture Points on Outcome and Prognosis of Severe Community-Acquired Pneumonia in the Elderly."

Related Drugs and Biologics

1.	Iron
2.	Aspirin (Acetylsalicylic Acid)
3.	Ferritins (Ferritin)
4.	Analgesics (Analgesic Drugs)
5.	Sodium
6.	Penicillins (Penicillin)
7.	Lipids
8.	Interferons
9.	Hydroxyurea (Hydrea)
10.	Chelating Agents

Related Therapies and Procedures

1.	Therapeutics
2.	Acupuncture Points (Acupuncture Point)
3.	Percutaneous Collagen Induction
4.	Punctures
5.	Ear Acupuncture