Blood Platelet Disorders (Thrombocytopathy)

06/01/1994 - "A study on the efficacy of a phospholipid solution in dogs with aspirin-induced thrombocytopathy."
09/01/2002 - "In this study of healthy male baboons, both the survival and function of autologous fresh, liquid-preserved, and cryopreserved platelets in the correction of an aspirin-induced thrombocytopathy was evaluated. "
01/01/1972 - "Studies on the metabolic mechanisms in aspirin-induced thrombocytopathy."
01/01/2014 - "We present two cases that were diagnosed with an aspirin-like defect as an inherited thrombocytopathy, even though their PFA-100 closure times were within the normal range. "
05/01/2009 - "[Clinical and laboratory aspects of the Aspirin-like defect as hereditary thrombocytopathy]."

12/01/1999 - "Although the number of patients is small, our study suggests that rFVIIa may be an alternative to platelet transfusions in patients with a severe congenital thrombocytopathy."
06/15/2005 - "Modification of biological parameters after treatment with recombinant factor VIIa in a patient with thrombocytopathy due to storage pool disease."
03/01/2005 - "In two patients with thrombocytopathy, rFVIIa helped to discriminate surgical bleeding from bleeding caused by a defect in hemostasis. "
09/20/1998 - "Recombinant Factor VIIa, a new therapeutic tool to treat severe bleeding caused by inhibitory haemophilia cases, some cases of thrombocytopenia and thrombocytopathy (e.g. "
03/01/2007 - "Recombinant activated factor VII (rFVIIa), originally developed for the treatment of life-threatening bleeding in hemophilic patients with inhibitors to factors VIII or IX, has been increasingly used to control hemorrhage unresponsive to conventional treatment, in the absence of a defined coagulopathy or thrombocytopathy. "

07/01/1977 - "Secondary disturbances of hemostasis occur in urosepsis as a consequence of an impairment of liver (hypoproduction of coagulation factors, decrease of the clearance of activated coagulation factors) and kidney function (thrombocytopathy by uremic toxins). "
08/01/2006 - "Coagulation factor defects, thrombocytopenia, and thrombocytopathy are associated with cirrhosis. "

01/01/2015 - "Renal insufficiency is characterized by thrombocytopathy, caused by the accumulation of water soluble and protein bound waste products of protein metabolism, which are not adequately eliminated by the kidney. "

11/01/2011 - "Desmopressin is well tolerated and affective in patients with VWD 1 and thrombocytopathy."
11/01/2011 - "[Desmopressin parenteral in patients with VWD1, VWD 2A and thrombocytopathy]."
05/01/2011 - "Despite about 3 decades of clinical experience with the therapy of inherited thrombocytopathies (HTP) with desmopressin (DDAVP) the mechanisms of haemostatic effects of DDAVP in these diseases remain unclear. "
11/01/2011 - "In the present study effectiveness of DDAVP was tested and side effects were recorded in patients with VWD 1, von Willebrand disease type 2 (VWD 2) or thrombocytopathy (TCP). "
05/01/2011 - "Evaluation of desmopressin effect on primary haemostasis in pediatric patients with aspirin-like defect as hereditary thrombocytopathy."

10/29/1988 - "Platelet aggregation studies do not permit etiologic diagnosis of the thrombocytopathy except for the well-defined membrane glycoprotein deficiencies. "

08/20/1976 - "Hemorrhage due to thrombocytopathies can in most cases be stopped by application of the homologous coagulation-active phospholipide complex Fibraccel, as shown in a study in which 78 patients suffering from various thrombocytopathies were checked. "

01/01/2016 - "Sticky platelet syndrome (SPS) is a prothrombotic thrombocytopathy with familial occurrence, characterized by hyperaggregability of platelets in response to adenosine diphosphate (ADP), epinephrine (EPI) or both. "
09/01/2013 - "Sticky platelet syndrome (SPS) is a thrombophilic thrombocytopathy with familial occurrence and autosomal dominant trait, characterized by an increased in vitro platelet aggregation in response to low concentrations of adenosine diphosphate (ADP) and/or epinephrine (EPI). "
01/01/1988 - "The leukemic patients were with a preliminary proved thrombocytopathy type "empty thrombocytic pool disease" which had been proved via aggregation measurement by the ATP and ADP levels in the thrombocytes and by the thrombocytic factor 4 level. "
01/01/1979 - "These findings suggest that the thrombocytopathy in our patient is due to an impaired ADP release from the platelet granules containing normal quantities of adenine nucleotides. "
01/01/1979 - "[Aspirin-like defect - a hereditary thrombocytopathy due to impaired release of platelet adenosine diphosphate]."

01/01/1998 - "[Thrombocytopathy due to defective response to thromboxane A2]."
01/01/1990 - "[Hereditary thrombocytopathy due to a thromboxane A2 deficiency in a newborn infant]."
06/01/1981 - "Constitutional thrombocytopathy with subnormal response to thromboxane A2."
03/01/1979 - "Thrombocytopathy in preleukaemia: association with a defect of thromboxane A2 activity."

09/21/2002 - "Because serotonin promotes platelet aggregation, too low an amount of serotonin in the platelets can result in thrombocytopathy. "
07/01/2002 - "In patients with preproliferative DR and central chorioretinal dystrophy serotonin insufficiency was associated with decreased concentration of serotonin and thrombocytopathy. "
07/01/2002 - "Serotonin insufficiency in patients with proliferative DR was paralleled by increased plasma serotonin concentration and thrombocytopathy. "
01/01/2008 - "The relationship of excessive bleeding during orthopaedic surgery secondary to thrombocytopathy and low levels of serotonin caused by drugs that inhibit the reuptake of serotonin is presented."
01/26/2015 - "These findings were suggestive of a mutation in the factor IX propeptide, but thrombocytopathy induced by selective serotonin re-uptake inhibitors could have worsened the bleeding. "

07/01/1998 - "After treatment the thrombocytopathy improved in 7 of 11 patients (63%), in four it persisted. "
06/15/2005 - "Modification of biological parameters after treatment with recombinant factor VIIa in a patient with thrombocytopathy due to storage pool disease."

12/01/1999 - "Although the number of patients is small, our study suggests that rFVIIa may be an alternative to platelet transfusions in patients with a severe congenital thrombocytopathy."

01/01/1964 - "[INDICATIONS FOR FRESH BLOOD TRANSFUSIONS IN BLOOD PLATELET DISORDERS]."
07/01/1978 - "[Characteristics of blood transfusion therapy in treating acute hemorrhage in thrombocytopathies]."
01/01/1950 - "[Success of a blood transfusion with silicone-treated syringe in a case of hemorrhagic thrombocytopathy: importance of silicone for survival of platelets after transfusion]."
01/01/1988 - "[The effectiveness of the combined treatment of thrombocytic hemorrhagic diathesis of dogs with prednisolone and blood transfusion in the model of an aspirin-produced thrombocytopathy]."

01/01/1983 - "[Modification of uremic thrombocytopathy by hemodialysis]."
10/01/1983 - "Scurvy and thrombocytopathy in a chronic hemodialysis patient."
08/01/2004 - "Hemodialysis, erythropoietin and megakaryocytopoiesis: factors in uremic thrombocytopathy and thrombophilia."

05/01/2001 - "Drug-induced thrombocytopathy can induce pathological hemorrhages in the perioperative period of ACS."