Biogenic Amines (Biogenic Amine)

A group of naturally occurring amines derived by enzymatic decarboxylation of the natural amino acids. Many have powerful physiological effects (e.g., histamine, serotonin, epinephrine, tyramine). Those derived from aromatic amino acids, and also their synthetic analogs (e.g., amphetamine), are of use in pharmacology.

Also Known As:

Networked: 706 relevant articles (8 outcomes, 57 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Shpakov, A O: 4 articles (01/2012 - 01/2005)
2.	Ormazábal, Aida: 3 articles (11/2015 - 08/2010)
3.	Artuch, Rafael: 3 articles (11/2015 - 08/2010)
4.	Andreeva, L A: 3 articles (02/2008 - 08/2003)
5.	Maslova, M V: 3 articles (08/2007 - 08/2003)
6.	Sokolova, N A: 3 articles (08/2007 - 08/2003)
7.	Goncharenko, E N: 3 articles (08/2007 - 08/2003)
8.	Graf, A V: 3 articles (08/2007 - 08/2003)
9.	Molero-Luis, Marta: 2 articles (11/2015 - 06/2013)
10.	García-Cazorla, Angels: 2 articles (11/2015 - 06/2013)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2008 - "The developed method has been successfully applied to the determination of biogenic amines in human plasma of three healthy volunteers and four cancer patients. " 01/01/2008 - "Biogenic amines occur in all living organisms and have an effect on the cell growth, although at high concentrations they can be toxic; some are used as cancer markers in health protection or as spoilage markers in foods. " 03/01/2001 - "Moreover, the presence of VMATs provides the basis for a diagnostic application of biogenic amine-derived tracers in positron emission tomography of SCLC tumors." 01/01/2001 - "The development of fluorescence procedures for detecting biogenic amines at the cellular level provided information about endocrine cell function of normal cells and related tumors. " 11/01/2000 - "Characteristics shared by these syndromes include the involved cell type, most of the tumors are composed of one or more specific polypeptide- and biogenic amine-producing cell types (APUD--amine precursor uptake and decarboxylation). "
2.	Rett Syndrome (Rett's Disorder) 01/01/1987 - "Reduction in cerebrospinal biogenic amine metabolites and characteristic alterations in respiratory, sleep, and EEG patterns were helpful in supporting the clinical diagnosis in the fifteen patients with typical features of Rett syndrome. " 01/01/1987 - "Reduced concentrations and increased metabolism of biogenic amines in a single case of Rett-syndrome: a postmortem brain study." 01/01/2010 - "Given our current knowledge and the tools available, modulating biogenic amine metabolism may prove to be the most promising strategy for improving the life quality of Rett syndrome patients in the short term." 01/01/2010 - "Biogenic amines appear to have an important role in the pathophysiology of Rett syndrome, for several reasons. " 01/01/2010 - "Biogenic amines in Rett syndrome: the usual suspects."
3.	Hypertension (High Blood Pressure) 04/01/1987 - "Platelets have the ability to take up, store and release biogenic amines and have therefore been used as models for neurons in studies of neuropsychiatric disorders and hypertension. " 06/01/1992 - "Biogenic amine metabolism may be altered in hypertension and thus contribute to its pathophysiology. " 01/01/1991 - "[Changes in kinetics of deaminated biogenic amines in spontaneous hypertension]." 12/01/1990 - "Biogenic amine depletion is now believed to underlie the organic nature of depression, and many of the drugs used to treat hypertension interfere with this system. " 08/01/1986 - "[External respiratory function, blood oxygenation and the biogenic amine content in different hemodynamic variants of hypertension]."
4.	Mood Disorders (Mood Disorder) 11/01/2001 - "The therapeutic utility of these agents supports biogenic amine theories of affective disorders and raises the question as to whether SERT and NET exhibit a functional genetic variation that could influence risk for behavioral disorders. " 03/26/1981 - "The implications of these findings for biogenic amine theories of affective disorders are discussed." 01/01/1980 - "Biogenic amines and affective disorders. " 01/01/1980 - "II. Role of changes in the biogenic amine system in the pathogenesis of affective disorders]." 03/01/1979 - "The significance of these results is discussed in relation to biogenic amine dysfunction in the major affective disorders."
5.	Epilepsy (Aura) 12/01/1983 - "A study of urinary excretion of biogenic amine metabolites in epilepsy." 01/01/1975 - "[The role of biogenic amines in the pathogenesis of epilepsy]." 03/01/1973 - "Brain concentrations and synthesis rates of biogenic amines during chronic cobalt experimental epilepsy in the rat." 11/01/2015 - "We did not find a link between rate of efficacy for the ketogenic diet and etiologies of epilepsy, nor did we find a link between the rate of efficacy for the ketogenic diet and cerebrospinal fluid pterins and biogenic amines concentrations. " 11/01/2015 - "The values of some amino acids were significantly different in relationship with the ketogenic diet efficacy; however, the epilepsy etiology and the cerebrospinal fluid biogenic amine and pterin values were not."

Related Drugs and Biologics

1.	Serotonin (5 Hydroxytryptamine)
2.	Norepinephrine (Noradrenaline)
3.	Hormones
4.	Antidepressive Agents (Antidepressants)
5.	Pterins
6.	Cations
7.	Adrenocorticotropic Hormone (ACTH)
8.	Hypothalamic Hormones
9.	Gastrointestinal Hormones (Hormones, Gastrointestinal)
10.	Histamine (Histamine Dihydrochloride)

Related Therapies and Procedures

1.	Ketogenic Diet
2.	Ligation
3.	Laser Therapy (Surgery, Laser)
4.	Renal Dialysis (Hemodialysis)
5.	Enterosorption