Biliary Fistula

03/01/1986 - "The present studies were undertaken 1) to assess the quantitative absorption of total bile acids in the portal vein of normally fed, unanesthetized pigs with an intact biliary tract and 2) to evaluate the effect of a chronic reentrant biliary fistula on absorption. "
04/01/1996 - "The steady-state absorption of eight conjugated bile acids from a perfused jejunal segment was measured in the anesthetized biliary fistula guinea pig. "
01/01/1996 - "The compound was administered intravenously to anesthetized biliary fistula rats at doses of 1, 3, or 5 mu mol/kg-min and to hamsters at 3 mu mol/min-kg. Biliary bile acids and radioactivity were analyzed by thin-layer chromatography (TLC), high pressure liquid chromatography (HPLC), and gas chromatography-mass spectrometry (GC-MS). "
03/01/1986 - "Enterohepatic circulation of bile acids in pigs: diurnal pattern and effect of a reentrant biliary fistula."
10/01/2003 - "In 15 out of 21 patients clinical symptoms improved after PEBD and liver function tests normalised (blood bile acids), 1 patient had to be converted to IB due to too high output biliary fistula, 2 patients were transplanted and 3 are considered for transplantation. "

01/01/1991 - "It was established that intravenous administration of antibiotics at the maximum dosages with purposeful sanation of the bile ducts via the external biliary fistula at the preoperative period improved the immediate and long-term results of treatment of the patients. "
10/01/2010 - "We report herein a case of thoraco diaphragmatico biliary fistula in a 24-year-old male who was managed conservatively with antibiotics and tube thoracostomy and had complete radiological clearance."
08/01/1996 - "Our policies include 1) meticulous and accurate dissection and enteric anastomosis at the porta hepatic with the use of hepatic mobilization, 2) use of a complete external biliary fistula (Sawaguchi method), 3) use of an intussusception-type anti-reflux valve in the Roux-en-Y limb, 4) prompt reoperation if necessary, 5) prolonged use of antibiotics and choleretics, 6) in-patient care for as long as 3 months after hepatic portoenterostomy, etc. 19 of 21 patients, treated at National Children's Hospital and University of Tokyo, became jaundice-free, and we conclude that these policies mentioned above are necessary to keep the jaundice-free ratio at 90%, not at 70% which is the average ratio at all Japanese institutions."
06/01/2014 - "For all patients blood samples were obtained before HBO treatment or the placebo procedure (T0); at the end of HBO session or placebo procedure (T1); on the first post-operative day (POD)(T2) and on seventh POD(T3) day, measuring interleukin (IL)-1, IL-6, IL-8, IL-10, IL-12 and TNF-α, recording postoperative pancreatic fistula (POPF), biliary-fistula, fever, intra-abdominal abscess, bleeding, pulmonary complications, delayed gastric emptying and requirement for post-operative antibiotics. "

04/01/1990 - "These results suggest that SMS 201-995 might be useful in the treatment of external biliary fistulas."
01/01/1996 - "Successful control of external biliary fistula by using SMS 201-995 in a child."
05/01/1995 - "In the patient with the biliary fistula a 30% reduction was observed twice following the administration of octreotide, and an increase occurred when it was withheld. "
01/01/1996 - "The use of Sandostatin in the management of a case of complicated biliary fistula is reported; it controlled the fistula reducing its daily output from 200 ml to less than 5 ml per day."
05/01/1995 - "Within 24 hours of octreotide treatment, a mean reduction of 52% in the intestinal fistulas' output, 40% in the pancreatic fistulas, and 30% in the biliary fistula was noted. "

08/01/1997 - "To assess the effect of side chain length on the metabolism and physiological effects of homologues of chenodeoxycholic acid (CDCA), dinorCDCA, the C22 homologue, was synthesized and its hepatic biotransformation, transport kinetics, and choleretic properties were defined in rat and hamster biliary fistula and in isolated perfused rat liver. "
06/25/1979 - "Incorporation of 18O in cholic anc chenodeoxycholic acid was determined after inhalation of 18O2 by rats with biliary fistula. "
04/15/1991 - "In subsequent in vivo studies, a model FBAL-BA conjugate, FBAL-chenodeoxycholate (FBAL-CDC), was introduced into the lumen of the small intestine of anesthetized rats with biliary fistulas to quantitate the intestinal absorption, metabolism and tissue distribution of the conjugate. "
02/01/1992 - "Radiolabeled chenodeoxycholic acid (CDC) and its N-acyl amidates with glycine (CDC-Gly) or taurine (CDC-Tau) were introduced into the lumen of the upper small intestine in the biliary fistula rats, and radioactive metabolites in bile, blood, urine, and tissues were identified and quantitated by high-performance liquid chromatography. "
02/01/1987 - "The biliary recovery and effect on bile flow and biliary bicarbonate secretion of infused norchenodeoxycholate (nor-CDC), the synthetically prepared C23 homologue of chenodeoxycholate (CDC), were defined in the anesthetized biliary fistula hamster, rat, and guinea pig and compared with those of its taurine conjugate as well as those of the natural C24 bile acid, CDC. "

12/01/1971 - "A case of rickets due to external biliary fistula--study on vitamin D effect upon Ca absorption and retention."
05/31/1938 - "Our experience indicates that vitamin A and vitamin D supplements do not correct the prothrombin deficiency in biliary fistula animals."

07/15/2006 - "Acute rat biliary fistula and chronic cholestasis induced by 17alpha-ethynyl-estradiol (17EE) models were used to study and compare the effects of UPF-680 (dose range 0.6-6.0 micromol/kg min) with UDCA on bile flow, biliary bicarbonate (HCO(3)(-)), lipid output, biliary bile acid composition, hepatic enzymes and organic anion pumps. "

04/01/2004 - "The aim of this study was to investigate the effects of melatonin or L-tryptophan on amylase secretion in vivo in anaesthetized rats with pancreato-biliary fistulas, and in vitro using isolated pancreatic acini. "

05/31/1938 - "Variations in the rate of prothrombin depletion in biliary fistula dogs kept on constant diet indicate the existence of additional factors which require further study. "
05/31/1938 - "In biliary fistula dogs the plasma prothrombin falls eventually to low levels and bleeding commonly occurs. "

04/01/2006 - "The extrahepatic biliary tree was first visualized in 1918 when Reich injected bismuth and petrolatum and defined a biliary fistula, thus opening the field for further studies of the biliary tree. "

04/01/2004 - "The aim of this study was to investigate the effects of melatonin or L-tryptophan on amylase secretion in vivo in anaesthetized rats with pancreato-biliary fistulas, and in vitro using isolated pancreatic acini. "

10/01/1994 - "In our experience the treatment of postoperative biliary fistula with a distal obstruction bile flow by endoscopic sphincterotomy is a safe and effective procedure, and should be recommended as the first option in those patients."
11/01/2014 - "Endoscopic sphincterotomy, biliary stenting, and nasobiliary tube drainage are effective for treating postoperative biliary fistulas."
06/01/2002 - "Endoscopic sphincterotomy is safe and effective and should be considered the minimally invasive procedure of choice for the management of postoperative biliary fistula due to HHD because it obviates the need for reoperation. "
01/01/2005 - "A biliary fistula appeared after 4 days and was successfully treated by endoscopic sphincterotomy. "
02/01/2003 - "In the majority of patients, endoscopic sphincterotomy allows healing of postoperative external biliary fistulas, and should be performed as early as possible. "

01/01/2000 - "Endoscopic biliary stent placement is a rapid, safe and effective treatment for persistent post-traumatic biliary fistula demonstrated by ERCP."
08/01/2010 - "This 10 F stent is superior to other endoscopic approaches in the treatment of biliary fistulas."
02/01/2013 - "No patients developed a biliary fistula, required percutaneous drainage, or had endoscopic stent placement. "
01/01/2012 - "Two patients developed a biliary fistula: one resolved spontaneously and the other required percutaneous drainage and an endoscopic biliary stent. "
10/01/2011 - "Management involved establishing a controlled biliary fistula followed by ERCP to confirm the nature of the injury and decompress the bile duct with stent insertion. "

05/01/2012 - "Treatment is focused on urgent laparotomy and resolution of the intestinal occlusion, leaving management of the biliary fistula to only selected cases."
10/01/1994 - "The only complication worth mentioning out of 27 choledocholithotomies performed is an external biliary fistula (3.7%) treated with a following laparotomy operation. "
03/01/2007 - "Biliary fistula occurred in two of the five thoracotomy patients surviving operation and in two laparotomy patients (2/6). "
11/01/2012 - "Once therapy was completed and the child was deemed free of disease, she underwent exploratory laparotomy with Roux-en-Y biliary cystenterostomy for definitive management, resulting in resolution of her biliary fistula, jaundice, and marked improvement in her nutritional status. "
08/01/1983 - "The present study was designed to evaluate the efficacy of chemotherapy by NCS for advanced and/or recurrent carcinoma of the pancreas, mainly nonresectable cases in which exploratory laparotomy or construction of biliary fistula were performed. "

03/01/2010 - "Placement of drains was effective in a considerable proportion of patients undergoing hepatectomy, with regard to reducing the frequency of development of subphrenic fluid collections and biliary fistula/biloma formation."
01/01/2016 - "The diagnosis and management of bile leaks after hepatectomy are heterogeneous because there is no agreement on the definition of post-hepatectomy biliary fistula. "
01/01/2014 - "One patient had biliary fistula after final hepatectomy. "
06/16/2001 - "The prevalence of biliary fistula was 11.2%, which was mainly related to the type of hepatectomy (major hepatectomy; p = 0.002) and a biliary-enteric anastomosis (p < 0.001). "
01/01/1992 - "[External biliary fistula after right lateral sectorial hepatectomy for liver injury. "

09/01/1996 - "Hepatic artery-biliary fistula during infusion chemotherapy."
08/01/2015 - "The biliary fistula/bile leakage was more frequent in laparoscopic intervention (P<0.001) and fever occurred more in PAIR plus chemotherapy patients."
08/01/1983 - "The present study was designed to evaluate the efficacy of chemotherapy by NCS for advanced and/or recurrent carcinoma of the pancreas, mainly nonresectable cases in which exploratory laparotomy or construction of biliary fistula were performed. "