Bile Reflux

09/01/2001 - "The symptom score and the acid and bile reflux improved significantly, whereas the motility parameters did not change during the study period. "
01/01/2022 - "Non-acid reflux has been associated with ESCC in small observational studies, and in animal models bile reflux can promote the development of ESCC. "
09/01/2011 - "The effect of the composition of reflux bile acids, especially the ratio of hydrophobic to hydrophilic ones, on the development of Barrett's oesophagus has not been fully investigated in human studies. "
01/01/2008 - "Esophageal motility, 24 hr pH study and Bilitec 2000, after 6 months of Nissen shows high significant increase in LESP, decrease in acid and bile reflux. "
05/01/2004 - "Posttherapeutic monitoring of acid and bile reflux is recommended in future clinical trials of PPI treatment vs laparoscopic antireflux surgery."

02/15/2015 - "Rabeprazole is effective for bile reflux oesophagitis after total gastrectomy in a rat model."
02/15/2015 - "With this model, rabeprazole is good effect for reflux esophagitis after total gastrectomy from bile reflux. "
03/01/2010 - "Rabeprazole combined with hydrotalcite is effective for patients with bile reflux gastritis after cholecystectomy."
03/01/2010 - "To assess the efficacy of rabeprazole and hydrotalcite in patients with bile reflux gastritis after cholecystectomy. "
03/01/2010 - "Rabeprazole combined with hydrotalcite is an effective therapeutic option in the treatment of patients with bile reflux gastritis after cholecystectomy."

01/01/2000 - "This in vivo study used controlled 'iatrogenic' episodes of bile reflux to determine the ability of the Bilitec system to detect bile acids in the oesophageal lumen. "
06/01/1990 - "In this study we measured the fasting total bile acid concentration (BAC) in gastric juice and used it to represent the bile reflux. "
07/20/2022 - "This paper reviews in detail the relationship between bile reflux and GIM and the mechanisms by which bile acids induce GIM."
07/20/2022 - "Bile reflux is also a pathogenic factor in GIM and can continuously irritate the gastric mucosa, and bile acids in refluxed fluid have been widely reported to be associated with GIM. "
01/01/2022 - "Our results demonstrate that bile reflux significantly alters the oral, gastric, and intestinal bile acids profiles but only influences the oral and gut microbiota composition. "

01/01/2019 - "Our results showed that impaired coordination between antral contraction and pyloric closure can result in delayed gastric emptying, rapid gastric emptying and bile reflux."
01/01/1979 - "Gastric ulceration following an antireflux fundoplication procedure is the result of bile reflux into the stomach and not a consequence of gas bloat, antral distention or hypergastrinemia. "
09/01/2001 - "Antral biopsies were examined "blind" to clinical group and graded for a series of histological features from which the "reflux gastritis score" (RGS) and "bile reflux index" (BRI) could be calculated. "
06/01/1999 - "These results suggest that bile reflux due to the disturbance of gastric antral movement is a cause of the spontaneous gastric ulcers in W/Wv mice."
04/01/1989 - "Manometric evaluation of the interdigestive antroduodenal motility in subjects with fasting bile reflux, with and without antral gastritis."

01/01/2010 - "These data suggest that ketamine may prevent LPS-induced gastric bleeding by decreasing bile reflux through improved intestinal transit or by local changes in nitric oxide, prostaglandin, and carbon monoxide metabolism."
01/01/1988 - "Offensive factors include NSAIDs, hydrochloric acid-peptic activity, bile reflux, and some products of the lipoxygenase pathway such as leukotriene B4; whereas defensive processes are largely mediated by prostaglandins through poorly understood mechanisms uniformly termed cytoprotection. "

02/01/1976 - "Speculation from animal models implicates bile reflux in aspirin-induced and shock-related gastric ulceration and assigns to bile a possible explanation, in part at least, for the apparent therapeutic efficacy of a carbenoxalone derivative and an antipepsin agent. "
01/01/1973 - "Bile reflux in gastric ulcer: the effect of smoking, metoclopramide and carbenoxolone sodium."

07/01/2021 - "The results of the network meta-analysis showed that Weiyankang capsules combined with hydrotalcite had the best effect in the treatment of bile reflux among the 14 interventions. "
03/01/2010 - "Rabeprazole combined with hydrotalcite is effective for patients with bile reflux gastritis after cholecystectomy."
03/01/2010 - "To assess the efficacy of rabeprazole and hydrotalcite in patients with bile reflux gastritis after cholecystectomy. "
03/01/2010 - "Rabeprazole combined with hydrotalcite is an effective therapeutic option in the treatment of patients with bile reflux gastritis after cholecystectomy."
03/01/2010 - "Postcholecystectomy patients with bile reflux gastritis confirmed by endoscopy and 24 h gastric bilirubin monitoring were randomly assigned to one of four eight-week treatments: observation (group A), rabeprazole alone (group B), hydrotalcite alone (group C) and rabeprazole in combination with hydrotalcite (group D). "

01/01/2010 - "These data suggest that ketamine may prevent LPS-induced gastric bleeding by decreasing bile reflux through improved intestinal transit or by local changes in nitric oxide, prostaglandin, and carbon monoxide metabolism."

01/01/2010 - "Ketamine improved intestinal transit, prevented LPS-induced bile reflux, and diminished gastric bleeding. "
01/01/2010 - "Ketamine suppresses LPS-induced bile reflux and gastric bleeding in the rat."
01/01/2010 - "We hypothesized that ketamine would improve LPS-induced ileus and therefore examined its effects on gastric emptying and intestinal transit as well as duodenogastric bile reflux and associated gastric bleeding. "
01/01/2010 - "These data suggest that ketamine may prevent LPS-induced gastric bleeding by decreasing bile reflux through improved intestinal transit or by local changes in nitric oxide, prostaglandin, and carbon monoxide metabolism."

01/01/2016 - "Moluodan improved dysplasia score in histopathology, and erythema and bile reflux score in endoscopy, and superior to folic acid in improving epigastric pain, epigastric suffocation, belching and decreased appetite. "

01/01/2006 - "Jejunal pouch interposition (JPI) reconstruction after total gastrectomy has proven effective for improving postoperative quality of life; however, evaluation of bile reflux into the esophagus shows that the reflux of digestive juice is not sufficiently prevented. "
07/01/2008 - "The aim of this study was to determine whether reconstruction methods after the distal subtotal gastrectomy influenced the degree of food residue and bile reflux. "
12/01/2002 - "The aim of this study was to investigate which reconstructive procedure would most effectively prevent bile reflux into the gastric remnant and esophagus after distal gastrectomy. "
03/01/2023 - "Proximal gastrectomy (PG) has been excluded from the arsenal of western surgical oncologists for fear of bile reflux and diet intolerance. "
12/01/2020 - "Therefore, we report a series of three cases that describe the development of BE after total gastrectomy and provides additional support on the role that bile reflux plays in patients with BE."

09/01/2008 - "Although it is more complex, the Roux-en Y procedure can prevent bile reflux, is safe, and is superior to the Billroth I procedure both functionally and symptomatically. "
09/15/2021 - "Roux-en-Y reconstruction probably reduces the incidence of bile reflux compared to Billroth-I reconstruction (RR 0.40, 95% CI 0.25 to 0.63; I² = 22%; 4 studies; 399 participants; moderate-certainty evidence). "
10/01/2023 - "Annual endoscopic findings revealed more residual food and less bile reflux in the delta group (P<0.001) than in the Billroth II group. "
01/01/2022 - "Furthermore, URY anastomosis was better than Billroth-II with Braun (OR = 0.07, 95%confidence interval (CI): [0.02, 0.28], P = 0.0001) and Billroth-II (OR = 0.14, 95%CI: [0.09, 0.24], P < 0.00001) anastomoses for preventing bile reflux. "
09/15/2021 - "Roux-en-Y reconstruction probably reduces the incidence of bile reflux into the remnant stomach compared to Billroth-I reconstruction. "

01/01/2023 - "The present study aims to investigate the relationship between bile reflux (BR) and diameter of the common bile duct (CBD) in patients after cholecystectomy. "
08/17/1985 - "In an experimental study the effect of cholecystectomy on bile reflux into the stomach was investigated. "
01/01/2023 - "The relationship between bile reflux and common bile duct diameter after cholecystectomy: a clinical case-control study."
03/01/2017 - "Cholecystectomy alters bile release dynamics from pulsatile meal-stimulated to continuous, and results in retrograde duodeno-gastric bile reflux (DGR). "
08/01/2009 - "Clinical and epidemiological data suggest a potential association between cholecystectomy (CCE) and augmented bile reflux. "

01/01/2021 - "Braun Procedure Is Effective in Treating Bile Reflux Following One Anastomosis Gastric Bypass: a Case Series."
04/01/2021 - "Bile reflux after one anastomosis gastric bypass surgery: A review study."
08/01/2002 - "Duodenogastric bile reflux after gastric bypass: a cholescintigraphic study."
12/01/1986 - "Our study demonstrates a significant discrepancy between bile reflux observed endoscopically and the histologic findings after gastric bypass surgery. "
09/10/2023 - "One anastomosis gastric bypass (OAGB) is mainly criticized for the supposed carcinogenic effect of bile reflux on the gastric pouch mucosa. "

05/01/2004 - "A long Henley's loop was more effective in preventing bile reflux than a long Roux-en-Y loop. "
05/01/1982 - "Although the Henley loops in this series of patients may have been too short to be completely effective in preventing bile reflux into the stomach, we prefer the Roux-en-Y diversion because it is technically easier and safer."
07/01/1983 - "Bile reflux and the Roux en Y anastomosis."
01/01/2023 - "Compared with traditional Roux-en-Y anastomosis, due to the high recanalization rate, the URY group developed more severe gastrointestinal symptoms, the incidence of bile reflux and the grade of residual gastritis increased and the incidence of postoperative RSS was not reduced."
11/01/1982 - "Combining antrectomy with a Roux-en-Y anastomosis prevents postoperative bile reflux gastritis and thereby the need for further revision on this account. "