Bacteriorhodopsins

Rhodopsins found in the PURPLE MEMBRANE of halophilic archaea such as HALOBACTERIUM HALOBIUM. Bacteriorhodopsins function as an energy transducers, converting light energy into electrochemical energy via PROTON PUMPS.

Also Known As:

Networked: 22 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Deyev, Sergey M: 1 article (01/2022)
2.	Frolova, Anastasiya Yu: 1 article (01/2022)
3.	Kakuev, Dmitry L: 1 article (01/2022)
4.	Martynov, Vladimir I: 1 article (01/2022)
5.	Pakhomov, Alexey A: 1 article (01/2022)
6.	Sungurova, Anna S: 1 article (01/2022)
7.	Hsu, Shan-Hui: 1 article (12/2021)
8.	Huang, Hung-Jin: 1 article (12/2021)
9.	Ko, Ling-Ning: 1 article (12/2021)
10.	Wong, Chui-Wei: 1 article (12/2021)

Related Diseases

1.	Dehydration (Water Stress) 02/03/1981 - "Photochemical studies of the effects of temperature, pH, and dehydration on the formation and back photoreaction of the M412 intermediate in the photocycle of light-adapted bacteriorhodopsin (bR570) are carried out. " 06/13/2003 - "This assignment is supported by an experiment showing interconversion of the species upon intentional dehydration and by crystallographic data, which have indicated an in-plane unit cell in 3D crystals comparable to that of dehydrated bacteriorhodopsin membranes. " 06/13/2003 - "Compositional heterogeneity reflects partial dehydration in three-dimensional crystals of bacteriorhodopsin." 11/01/2000 - "Water and carboxyl group environments in the dehydration blueshift of bacteriorhodopsin." 04/28/1994 - "Blue form of bacteriorhodopsin and its order-disorder transition during dehydration."
2.	Rupture 01/31/2023 - "To identify factors that determine the force rupture levels in force-induced membrane protein unfolding, we applied our near-atomic-level Upside molecular dynamics package to study the vertical and lateral pulling of bacteriorhodopsin (bR) and GlpG, respectively. "
3.	Metrorrhagia (Spotting) 04/15/2006 - "The three main results of our study concern: 1), reliable functionalization of micromechanical cantilever arrays with proteoliposomes using ink jet spotting; 2), successful detection of the prosthetic retinal removal (bleaching) from the bacteriorhodopsin protein by measuring the induced nanomechanical surface stress change; and 3), the quantitative response thereof, which depends linearly on the amount of removed retinal. "
4.	Neoplasms (Cancer) 01/01/2022 - "It was reported earlier that a bacteriorhodopsin-derived pH low insertion peptide (pHLIP) targets acidic tumors and has the ability to translocate low molecular weight cargoes across the cancer cell membrane. " 01/14/2020 - "A peptide corresponding to bacteriorhodopsin (bR) helix C, later named pHLIP, inserts across lipid bilayers as a monomeric α-helix at acidic pH, but is an unstructured surface-bound monomer at neutral pH. As a result of such pH-responsiveness, pHLIP targets acidic tumors and has been used as a vehicle for imaging and drug-delivery cargoes. "
5.	Carcinogenesis 07/01/2001 - "Molecular Science of the Living Organism was presented in the case of G-proteins: i.e., the atomically controlled mechanism of 1. the carcinogenesis which originates from the point mutation of ras p21, 2. the activation of a receptor protein at the cell membrane, especially in the case of bacteriorhodopsin, 3. the activation of an inactive G-protein by the activated receptor protein."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Membrane Proteins (Integral Membrane Proteins)
3.	Retinaldehyde (Retinal)
4.	proteoliposomes
5.	Peptides (Polypeptides)
6.	Schiff Bases (Schiff Base)
7.	Aromatic Amino Acids (Aromatic Amino Acid)
8.	GTP-Binding Proteins (G-Protein)
9.	Protons (Proton)
10.	Muramidase (Lysozyme)