Azo Compounds

09/01/1952 - "[Cytological study of the azo dye hepatoma of rat through the course of its development]."
10/01/1989 - "Azo-dye-induced primary hepatoma and a gradual increase in thermosensitivity."
08/15/1974 - "Activation by reductive cleavage of potentially cytotoxic azo compounds by human hepatocellular carcinoma."
12/01/1973 - "Humoral cytotoxic factor in isograft immunity against azo-dye induced hepatoma."
07/01/1972 - " Administration of azo dye to 6-week-old rats for 10 weeks also decreased AFP in serum to undetectable levels over the next 2 weeks, except in 2 of 45 rats who developed large hepatomas early and remained positive. "

07/01/2017 - "Significant decreases in inflammation and a noticeable improvement in the liver, kidney, spleen, and small intestine of rats treated with LAB and food azo dyes simultaneously were observed. "
02/28/1996 - "Non-steroidal anti-inflammatory drugs have widespread cross-reactions with aspirin, while azo-dyes and food preservatives may induce a similar chronic inflammation of the airways. "

01/01/1972 - "Model studies for azo dye carcinogenesis."
04/01/1966 - "Studies on the hepatocyte in azo dye carcinogenesis."
07/01/1963 - "Studies on azo-dye carcinogenesis in rat liver. "
01/01/2012 - "This review highlights how azo dyes are metabolized by intestinal bacteria, mechanisms of azo reduction, and the potential contribution in the carcinogenesis/mutagenesis of the reduction of the azo dyes by intestinal microbiota."
02/16/2000 - "For the 17 azo compounds, the assay was positive in at least one organ; (1) 14 and 12 azo compounds induced DNA damage in the colon and liver, respectively, (2) the genotoxic effect of most of them was greatest in the colon, and (3) there were high positive responses in the gastrointestinal organs, but those organs are not targets for carcinogenesis. "

03/01/2023 - "This study may focus the attention on azo-dye agents that may represent an insufficient exploited source of agents for cancer treatment."
05/01/1952 - "A study of the inhibition of tumor growth in mice and rats with azo compounds."
06/01/1951 - "Study of liver tumor development and histologic changes in other organs in rats fed azo dye 3-methyl-4-dimethylaminoazobenzene."
01/01/2023 - "Molecular docking analysis of the oral tumor target JAK STAT 3 with oxo-azo compounds."
07/01/2021 - "Biofabricated CuONPs may therefore be an important biomedical research for the aid of bacterial/cancer diseases and photocatalytic degradation of azo dyes."

01/01/2008 - "The NAT2 distribution observed in the 83 cases is comparable to the proportion in 40 occupationally exposed bladder cancer cases in a Department of Urology located close to a former German production site of benzidine-based azo dyes, but higher than in most studies involving NAT2 genetic status in bladder cancer cases."
09/01/2001 - " In this study, 88% of cases and 65% of controls were of the "slow" acetylation and phenotype, The result point to and impact of the slow acetylation status as an individual risk factor for bladder cancer in persons occupationally exposed to amounts of carcinogenic aromatic amines released from water-soluble azo dyes."
01/01/2012 - "Bladder cancer may be produced by azo dyes due to the presence of carcinogenic aromatic amines. "
01/01/2012 - "Bladder cancer in crack testers applying azo dye-based sprays to metal bodies."
01/01/2008 - "Occupational exposure to aromatic amines is a known bladder cancer risk factor, whereas the impact of exposure to azo dyes, which may release aromatic amines in humans, is at present controversial. "