Azinphosmethyl (Azinphos-Methyl)

An organothiophosphorus cholinesterase inhibitor. It has been used as an acaricide and as an insecticide.

Also Known As:

Azinphos-Methyl; Guthion; Azinphos Methyl; Phosphorodithioic acid, O,O-dimethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) ester

Networked: 11 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - Organophosphates: 1942
    - Organothiophosphates: 1
      - Azinphosmethyl: 11
        azinphos ethyl
        azinphosmethyl oxon
  - Organothiophosphorus Compounds
    - Organothiophosphates: 1
      - Azinphosmethyl: 11
        azinphos ethyl
        azinphosmethyl oxon
- Sulfur Compounds: 278
  - Organothiophosphorus Compounds
    - Organothiophosphates: 1
      - Azinphosmethyl: 11
        azinphos ethyl
        azinphosmethyl oxon

Experts

1.	Adole, Prashant Shankarrao: 1 article (01/2021)
2.	Bora, Sushmita: 1 article (01/2021)
3.	Chaudhari, Vinod Ashok: 1 article (01/2021)
4.	Bishop, C A: 1 article (01/2005)
5.	Cheng, K M: 1 article (01/2005)
6.	Elliott, J E: 1 article (01/2005)
7.	Gill, H: 1 article (01/2005)
8.	Williams, T D: 1 article (01/2005)
9.	Liburd, O E: 1 article (08/2001)
10.	Stelinski, L L: 1 article (08/2001)

Related Diseases

1.	Chromosome Breakage 12/01/1976 - "In WI-38 cells, dosages of 120, 140 and 160 microng/ml of guthion were effective in inducing an average chromosome breakage of 0.042, 0.058 and 0.165 respectively per cell. "
2.	Anemia 01/01/2005 - "The main results of our study were as follows: (1) azinphos-methyl alone caused a dose-dependent inhibition of plasma and brain ChE activity; (2) p,p'-DDE in combination with azinphos-methyl did not change azinphos-methyl inhibition of ChE activity; and (3) there were suggestions of immunostimulation in birds dosed 1 year previously to p,p'-DDE and of anemia when p,p'-DDE was combined with azinphos-methyl; however, there was no dose-response for these parameters in birds subsequently dosed with p,p'-DDE."
3.	Neoplasms (Cancer) 01/01/1978 - "It is concluded that under the conditions of this bioassay, neoplasms of the thyroid and pancreatic islets suggest but do not provide sufficient evidence for the carcinogenicity of azinphosmethyl in male Osborne-Mendel rats. " 01/01/1978 - "The incidences of tumors of the pancreatic islets and of the follicular cells of the thyroid in the male rats suggest, but do not clearly implicate, azinphosmethyl as a carcinogen in these animals. " 07/01/1978 - "Of these, only nitrofen significantly increased the incidence of neoplasms of the exocrine pancreas of rats or mice (female Osborne-Mendel rats); azinphosmethyl was the only agent tested which significantly increased the incidence of islet-cell tumors of rats or mice (male Osborne-Mendel rats). "
4.	Teratogenesis 08/01/1994 - "The development of Xenopus laevis (African clawed frog) embryos exposed to the pesticide Guthion (technical grade) and Guthion 2S (commercial formulation) was evaluated in modified Frog Embryo Teratogenesis Assay--Xenopus (FETAX) tests. "
5.	Fetal Weight 01/01/1985 - "Fetal weight was reduced in three instances (cacodylic acid, endrin, and guthion), while the incidence of terata was markedly elevated for two (cacodylic acid and kepone). "

Related Drugs and Biologics

1.	Dichlorodiphenyl Dichloroethylene (DDE)
2.	Azinphosmethyl (Azinphos-Methyl)
3.	Insecticides
4.	Dimethoate (Rogor)
5.	Diazinon (Dimpylate)
6.	Benomyl
7.	benzimidazole
8.	pirimiphos methyl (Aktel)
9.	Pesticides
10.	Parathion (Ethyl Parathion)