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Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)

A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)
Also Known As:
Attention Deficit Hyperactivity Disorder; Attention Deficit Disorder; Hyperkinetic Syndrome; Disorder, Attention Deficit; ADDH; Attention Deficit Disorders with Hyperactivity; Attention Deficit Hyperactivity Disorders; Attention Deficit-Hyperactivity Disorder; Attention Deficit Disorders; Attention Deficit-Hyperactivity Disorders; Deficit Disorder, Attention; Deficit Disorders, Attention; Deficit-Hyperactivity Disorder, Attention; Deficit-Hyperactivity Disorders, Attention; Disorder, Attention Deficit-Hyperactivity; Disorders, Attention Deficit; Disorders, Attention Deficit-Hyperactivity; Dysfunction, Minimal Brain; Syndromes, Hyperkinetic; ADHD; Brain Dysfunction, Minimal; Minimal Brain Dysfunction
Networked: 13588 relevant articles (1538 outcomes, 4195 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
2. Schizophrenia (Dementia Praecox)
3. Oppositional Defiant Disorder
4. Epilepsy (Aura)
5. Tic Disorders (Tic Disorder)

Experts

1. Faraone, Stephen V: 220 articles (03/2022 - 01/2002)
2. Biederman, Joseph: 180 articles (01/2022 - 01/2002)
3. Arnold, L Eugene: 123 articles (09/2022 - 05/2002)
4. Banaschewski, Tobias: 109 articles (01/2022 - 01/2004)
5. Buitelaar, Jan K: 96 articles (01/2022 - 01/2004)
6. Newcorn, Jeffrey H: 95 articles (03/2022 - 04/2002)
7. Swanson, James M: 95 articles (02/2022 - 01/2002)
8. Cortese, Samuele: 83 articles (12/2022 - 08/2005)
9. Asherson, Philip: 82 articles (06/2022 - 04/2002)
10. Findling, Robert L: 79 articles (12/2022 - 03/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Attention Deficit Disorder with Hyperactivity:
1. Methylphenidate (Ritalin)FDA LinkGeneric
2. Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric
3. Guanfacine (Tenex)FDA LinkGeneric
4. Amphetamine (Amfetamine)FDA LinkGeneric
5. Lisdexamfetamine DimesylateFDA Link
6. Norepinephrine (Noradrenaline)FDA LinkGeneric
7. Dopamine (Intropin)FDA LinkGeneric
8. Dextroamphetamine (Dexedrine)FDA LinkGeneric
01/01/2018 - "In contrast, we found no evidence to suggest that dexamphetamine reduced the severity of ADHD symptoms (SMD -0.24, 95% CI -0.80 to 0.32; one study, 49 participants; very low-quality evidence). "
05/01/2008 - "In a placebo-controlled study in children with ADHD, less intersubject variability in T(max), C(max), and AUC from time zero to the last quantifiable concentration was seen in the 8 subjects who received LDX (percent coefficient of variation, 15.3, 20.3, and 21.6, respectively) compared with the 9 subjects who received MAS-XR (52.8, 44.0, and 42.8).In 2 clinical trials, significantly greater improvements in teacher and parent ratings of ADHD symptoms were seen with LDX compared with placebo (P<0.001).A study of the abuse potential of LDX evaluated subjective responses to the effects of oral LDX and immediate-release d-amphetamine in adults with a history of stimulant abuse. "
04/01/2006 - "ADHD symptoms improved with dextroamphetamine. "
11/01/2023 - "Correction to: d-Amphetamine Transdermal System in Treatment of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: Secondary Endpoint Results and Post Hoc Effect Size Analyses from a Pivotal Trial, by Cutler et al. J Child Adolesc Psychopharmacol 2023;33(5):176-182; doi: 10.1089/cap.2023.0005."
01/01/2023 - "d-Amphetamine Transdermal System in Treatment of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: Secondary Endpoint Results and Post Hoc Effect Size Analyses from a Pivotal Trial."
9. Bupropion (Wellbutrin)FDA LinkGeneric
10. Modafinil (Provigil)FDA Link

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Neurofeedback
4. Transcranial Direct Current Stimulation
5. Cognitive Training