Arteriovenous Malformations (Arteriovenous Malformation)

Abnormal formation of blood vessels that shunt arterial blood directly into veins without passing through the CAPILLARIES. They usually are crooked, dilated, and with thick vessel walls. A common type is the congenital arteriovenous fistula. The lack of blood flow and oxygen in the capillaries can lead to tissue damage in the affected areas.

Also Known As:

Networked: 1543 relevant articles (54 outcomes, 75 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Intracranial Aneurysm (Cerebral Aneurysm)
2.	Hemorrhage
3.	Aneurysm (Aneurysms)
4.	Hydrocephalus (Hydrocephaly)
5.	Neoplasms (Cancer)

Experts

1.	Young, William L: 28 articles (03/2014 - 07/2002)
2.	Lawton, Michael T: 19 articles (02/2013 - 04/2003)
3.	Yang, Guo-Yuan: 12 articles (02/2010 - 04/2003)
4.	Do, Young Soo: 11 articles (12/2013 - 05/2005)
5.	Pawlikowska, Ludmila: 10 articles (06/2013 - 10/2005)
6.	McCulloch, Charles E: 10 articles (12/2012 - 10/2005)
7.	Su, Hua: 9 articles (03/2014 - 12/2008)
8.	Kim, Helen: 9 articles (06/2013 - 10/2007)
9.	Mulliken, John B: 8 articles (03/2014 - 12/2003)
10.	Park, Kwang Bo: 8 articles (12/2013 - 06/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Arteriovenous Malformations:

1.	Ethanol (Ethyl Alcohol)IBA 03/01/2008 - "Ethanol embolization is effective for the treatment of pelvic arteriovenous malformations, though there is a chance of a major complication." 06/01/1997 - "The goal was to determine the safety and efficacy of absolute ethyl alcohol treatment in the management of intra-axial brain arteriovenous malformations (AVMs). " 07/01/2015 - "Absolute Ethanol Embolization of Infiltrating-diffuse Extracranial Arteriovenous Malformations in the Head and Neck." 06/01/2015 - "Absolute ethanol embolization of arteriovenous malformations in the periorbital region." 06/01/2014 - "Obvious change of HR and BP were observed before and after injection of absolute ethanol into arteriovenous malformation. "
2.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 05/01/1987 - "The photothrombotic technique may be useful in the treatment of arteriovenous malformations owing to its significant enhancement of the efficiency and permanency of vessel occlusion." 11/01/2014 - "This study explored the value of using a vessel fusion technique for visualizing and evaluating the vessel structure of patients diagnosed with arteriovenous malformations (AVMs). " 04/01/2015 - "Here we report spontaneous regression in size of both the feeder vessel and the vascular bed of the congenital hepatic arteriovenous malformation. " 10/01/2013 - "Intramuscular small vessel arteriovenous malformation of the left ventricle in an asymptomatic adolescent: a case report and literature review." 08/01/2013 - "Abnormal vessel of the ear associated with congenital arteriovenous malformation in the postauricular region."
3.	OxygenIBA 01/01/2009 - "The benefits of additional pulsatile pulmonary blood flow include the potential growth of pulmonary arteries, possible improvement in arterial oxygen saturation, and possible prevention of development of pulmonary arteriovenous malformations. " 03/01/2010 - "To evaluate the efficacy of susceptibility-weighted (SW) magnetic resonance (MR) imaging for the assessment of the posttreatment change in oxygen saturation in the draining vein in patients with spinal arteriovenous malformation (AVM). " 11/01/1995 - "The purpose of this study was to determine the effects of percutaneous transcatheter coil embolization of pulmonary arteriovenous malformations on arterial oxygen saturation, pulmonary gas exchange, anatomic right-to-left shunt, and lung function and to assess the complications of the procedure. " 01/01/1989 - "Positron emission tomography studies of changes in cerebral blood flow and oxygen metabolism in arteriovenous malformation of the brain." 01/05/2010 - "Endovascular embolization of pulmonary arteriovenous malformations can significantly improve blood oxygen saturation and reduce serious complications such as cerebral infaction. "
4.	Indocyanine Green (Cardio-Green)FDA LinkGeneric 11/01/2015 - "Role of intraoperative indocyanine green video-angiography to identify small, posterior fossa arteriovenous malformations mimicking cavernous angiomas. " 03/01/2015 - "The potential utility of intraoperative microscope-integrated indocyanine green (ICG) fluorescence angiography in the surgery of brain arteriovenous malformations (AVMs) and evaluation of the completeness of resection is debatable. " 03/01/2015 - "Comparison of indocyanine green fluorescent angiography to digital subtraction angiography in brain arteriovenous malformation surgery." 02/01/2015 - "To evaluate the quantitative assessment of flow dynamics during surgery for arteriovenous malformations (AVMs) with FLOW 800 with indocyanine green videoangiography. " 01/01/2015 - "Usefulness of repetitive intraoperative indocyanine green-based videoangiography to confirm complete obliteration of micro-arteriovenous malformations."
5.	EnbucrilateIBA 07/01/2009 - "The aim of this study was to analyze the histopathological changes in a consecutive series of 32 patients with brain arteriovenous malformations that were resected after undergoing endovascular embolization (22 using Onyx and 10 using N-butyl cyanoacrylate [NBCA]). " 04/01/2015 - "Dosimetric measurements of an n-butyl cyanoacrylate embolization material for arteriovenous malformations." 11/01/2014 - "[A case of arteriovenous malformation of the pancreas treated with n-butyl-2-cyanoacrylate transcatheter arterial embolization]." 01/01/2014 - "Pancreatic arteriovenous malformation (AVM) was diagnosed based on the findings of contrast-enhanced computed tomography (CT) and angiography, and transcatheter arterial embolization (TAE) with N-butyl-2-cyanoacrylate (NBCA) was performed without complications. " 01/01/2014 - "A successful case of transcatheter arterial embolization with n-butyl-2-cyanoacrylate for pancreatic arteriovenous malformation."
6.	Gadolinium DTPA (Magnevist)FDA Link 11/01/1992 - "In the spine, T2-weighted images and MR-angiography were too insensitive to detect arteriovenous malformations, whereas gadolinium-DTPA first-pass studies sensitively detected the malformation and the changes after embolizations." 11/01/1992 - "The combination of T2-weighted images, MR angiography, and gadolinium-DTPA first-pass studies nicely demonstrated the arteriovenous malformations and the effect of embolisation which ranged from negligible to almost complete. " 12/01/1993 - "Gadolinium-DTPA enhanced magnetic resonance imaging of dural sinus occlusion in dural arteriovenous malformation: a case report." 04/01/1990 - "[A case of spinal dural arteriovenous malformation associated with the broad lesion within spinal cord--diagnostic value of MRI with Gd-DTPA enhancement]." 10/01/1989 - "(4) Gd-DTPA was found to be effective in enhancing MRI in all cases of spinal cord tumors with exception of two cases of arteriovenous malformations. "
7.	Protons (Proton)IBA 04/01/2013 - "The present study investigated whether brain temperature measured by proton magnetic resonance (MR) spectroscopy can detect cerebral hemodynamic impairment in patients with arteriovenous malformations (AVMs) as shown by single photon emission computed tomography (SPECT). " 01/01/2016 - "Positive correlation between occlusion rate and nidus size of proton beam treated brain arteriovenous malformations (AVMs)." 01/01/2013 - "[Proton three-demensional conformal radiosurgery of arteriovenous malformation of the brain]." 01/01/2011 - "Long-term outcome of proton beam radiosurgery for arteriovenous malformations larger than 30 mm in diameter." 01/01/2011 - "The report discusses the results of proton stereotactic irradiation in 27 children, aged 6-15 (mean--12.5 yrs.), and 21 adults, aged 16-47 (mean--23 yrs.), with arteriovenous malformations (AVM) in the brain. "
8.	PolymersIBA 09/01/1986 - "Uterine arteriovenous malformation successfully embolized with a liquid polymer, isobutyl 2-cyanoacrylate." 11/01/2002 - "To determine efficacy, safety, and requirements for adjunctive embolization or surgery in the treatment of symptomatic arteriovenous malformations (AVMs) with superabsorbent polymer microsphere (SAP-MS) particles. " 11/01/2002 - "Embolization of high flow arteriovenous malformations: experience with use of superabsorbent polymer microspheres." 05/01/1994 - "Hydrophilic polymer-coated guide wire combined with progressive suppleness pursil catheter for safer, more definitive embolisation of arteriovenous malformations." 01/01/2002 - "The present study deals with the synthesis and characterization of radiopaque polymers which could, when solubilized in an appropriate water-miscible solvent, be useful embolic materials for the treatment of cerebral aneurysms and arteriovenous malformations. "
9.	Bucrylate (Bucrilate)IBA 01/01/1986 - "Improved technique of bucrylate embolisation in brain arteriovenous malformation. " 09/01/1986 - "A toxicologic-pathologic study of isobutyl-2-cyanoacrylate (Bucrylate) was carried out first in dogs and then in humans whose arteriovenous malformations were infused with this embolic agent. " 01/01/1990 - "Revascularization of brain arteriovenous malformations after embolization with bucrylate." 01/01/1990 - "The experience with embolization of intracerebral arteriovenous malformations (AVMs) with bucrylate (isobutyl-2-cyanoacrylate) in 29 patients is reported. " 09/01/1986 - "Bucrylate offers a number of advantages over other agents previously used to embolize uterine arteriovenous malformations."
10.	GadoliniumIBA 01/01/2004 - "Gadolinium-enhanced MR angiography of spinal arteriovenous malformation." 06/01/2002 - "Three-dimensional gadolinium-enhanced magnetic resonance angiography of pulmonary arteriovenous malformation." 04/01/2001 - "To determine whether three-dimensional gadolinium-enhanced magnetic resonance (MR) angiography could be used to identify pulmonary arteriovenous malformations (PAVMs) and to accurately identify the size and number of feeding arteries. " 04/01/2001 - "Pulmonary arteriovenous malformations: three-dimensional gadolinium-enhanced MR angiography-initial experience." 01/01/2000 - "Pelvic arteriovenous malformations: gadolinium-enhanced three-dimensional MR angiography findings."

Therapies and Procedures

1.	Therapeutic Embolization 11/01/2000 - "To assess the long-term efficacy of embolotherapy in combination with surgery for management of symptomatic high-flow arteriovenous malformations (HFAVMs) of the lower and upper extremities. " 04/01/1983 - "Balloon embolotherapy provided an effective treatment for pulmonary arteriovenous malformations regardless of anatomic type." 02/01/2001 - "Transcatheter embolotherapy of maternal pulmonary arteriovenous malformations performed by an experienced radiologist appears to be safe and effective after 16 weeks of gestational age." 02/01/2001 - "To determine if transcatheter embolotherapy is safe and effective for the treatment of pulmonary arteriovenous malformations during pregnancy. " 06/01/2012 - "To retrospectively evaluate the efficacy of embolotherapy in patients with iatrogenic traumatic uterine arteriovenous malformations (AVMs). "
2.	Sclerotherapy 08/01/2015 - "Management of scrotal arteriovenous malformation with transcatheter embolisation coils and percutaneous sclerotherapy under angiographic guidance." 12/01/2013 - "Slow-flow VMs (venous and lymphatic malformations) are often treated by sclerotherapy, whereas fast-flow lesions (arteriovenous malformations) are generally managed with embolization. " 07/01/2012 - "Extravascular injection of sclerotic agents does not affect vessels in the rat: experimental implications for percutaneous sclerotherapy of arteriovenous malformations." 06/01/2010 - "Sclerotherapy can be used in the outpatient clinic to treat arteriovenous malformations that have a slow flow or a venous outflow that can be compressed to artificially slow the flow during injection." 06/01/2010 - "Two cases with arteriovenous malformations of the face regions are presented in whom percutaneous sclerotherapy was performed under local anaesthesia in the outpatient clinic. "
3.	Catheters 05/01/1994 - "For safe, more definitive embolisation of arteriovenous malformations, improved selectivity of the catheter is desirable. " 10/01/2015 - "On initial MRI a grade 4 arteriovenous malformation (AVM) was identified in the right occipital lobe, which was further characterized by catheter angiography. " 09/01/2015 - "The US Food and Drug Administration recently approved a detachable-tip microcatheter, the Apollo microcatheter (eV3, Inc, Irvine, California), to prevent catheter entrapment during embolization of brain arteriovenous malformations (AVMs) using liquid embolic systems. " 12/01/2014 - "Liquid embolization using Onyx® of brain arteriovenous malformations (AVMs) is sometimes limited by micro catheter retention by Onyx® cast during the disengagement process. " 12/01/2014 - "Liquid embolization of brain arteriovenous malformation using novel detachable tip micro catheter: a technical report."
4.	Craniotomy 11/01/2015 - "Awake Craniotomy in Arteriovenous Malformation Surgery: The Usefulness of Cortical and Subcortical Mapping of Language Function in Selected Patients." 01/01/2015 - "The Spetzler-Martin arteriovenous malformation (AVM) grading system has proven to be useful in guiding treatment of cerebral AVMs with craniotomy. " 01/01/2014 - "We report the case of a 46 year-old woman presenting with unilateral postoperative visual loss after right frontal craniotomy for resection of an arteriovenous malformation in the supine position. " 01/01/2004 - "The patient was operated on via a temporo-parietal craniotomy and an arteriovenous malformation surrounded by abnormal glial tissue was observed during the exposure. " 01/01/2003 - "Dural arteriovenous malformation occurring after craniotomy for pial arteriovenous malformation."
5.	Particle Accelerators 07/01/2000 - "To prospectively demonstrate the safety and efficacy of stereotactic radiosurgery for arteriovenous malformations (AVMs) of the brain with a linear accelerator fitted with a multileaf collimator. " 01/01/2015 - "The aim of this study was to evaluate the clinical outcome of patients undergoing single-dose reirradiation using the Linear Accelerator (LINAC) for brain arteriovenous malformations (AVM). " 11/01/2011 - "This study demonstrates that complete obliteration of the nidus following linear accelerator-based stereotactic radiosurgery for arteriovenous malformations appears to be most closely related to the prescribed marginal dose. " 07/01/2014 - "Linear accelerator-based radiosurgery alone for arteriovenous malformation: more than 12 years of observation." 02/01/2009 - "We performed a retrospective study of 46 consecutive patients with more than 14 ml of arteriovenous malformations who were treated with radiosurgery using a linear accelerator and gamma knife (GK). "