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Arteriosclerosis

Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
Also Known As:
Arterioscleroses
Networked: 3850 relevant articles (97 outcomes, 344 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hypertension (High Blood Pressure)
2. Obesity
3. Inflammation (Inflammations)
4. Neoplasms (Cancer)
5. Cardiovascular Diseases (Cardiovascular Disease)

Experts

1. Ensminger, Stephan M: 18 articles (01/2022 - 01/2002)
2. Shimokawa, Hiroaki: 17 articles (01/2016 - 02/2002)
3. Xu, Qingbo: 13 articles (12/2020 - 01/2002)
4. Spriewald, Bernd M: 13 articles (01/2015 - 01/2002)
5. Weyand, Michael: 12 articles (01/2022 - 01/2003)
6. Tellides, George: 12 articles (01/2014 - 03/2004)
7. Pober, Jordan S: 10 articles (11/2011 - 03/2004)
8. Wood, Kathryn J: 10 articles (07/2010 - 01/2002)
9. Valdivielso, Pedro: 9 articles (11/2022 - 03/2011)
10. Hu, Yanhua: 9 articles (12/2020 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Arteriosclerosis:
1. CholesterolIBA
2. LipidsIBA
3. proanthocyanidinIBA
4. Antihypertensive Agents (Antihypertensives)IBA
5. Lipoproteins (Lipoprotein)IBA
6. Biomarkers (Surrogate Marker)IBA
7. rho-Associated KinasesIBA
01/01/2013 - "In a series of experimental and clinical studies, it has been demonstrated that Rho-kinase-mediated pathway plays an important role in various cellular functions not only in vascular smooth muscle hyperconstriction but also in actin cytoskeleton organization, cell adhesion and motility, cytokinesis, and gene expressions, all of which may be involved in the pathogenesis of arteriosclerosis. "
04/01/2007 - "In a series of experimental and clinical studies, we have demonstrated that Rho-kinase-mediated pathway plays an important role in various cellular functions, not only in vascular smooth muscle hyperconstriction but also in actin cytoskeleton organization, cell adhesion and motility, cytokinesis, and gene expression, all of which may be involved in the pathogenesis of arteriosclerosis. "
08/01/2004 - "Recent studies have demonstrated that upregulated Rho-kinase plays an important role in the pathogenesis of arteriosclerosis and vasospasm in both animals and humans. "
08/01/2004 - "Since inflammatory mechanisms have been implicated in the pathogenesis of arteriosclerosis and vasospasm, we examined whether inflammatory stimuli upregulate Rho-kinase in vitro and in vivo. "
03/01/2002 - "Accumulating evidence has demonstrated that the Rho/Rho-kinase-mediated pathway plays an important role in various cellular functions, not only in vascular smooth muscle contraction but also in actin cytoskeleton organization, cell adhesion and motility, cytokinesis, and gene expressions, all of which may be involved in the pathogenesis of arteriosclerosis/atherosclerosis. "
8. Fish OilsIBA
9. Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
10. Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA

Therapies and Procedures

1. Therapeutics
2. Transplantation
3. Heart Transplantation (Grafting, Heart)
4. Kidney Transplantation
5. Drug Therapy (Chemotherapy)