Arachnidism (Spider Bite)

10/01/2004 - "Additional considerations in presumptive brown recluse spider bites and dapsone therapy."
02/01/1985 - "Dapsone in the treatment of presumed brown recluse spider bite of the eyelid."
01/01/1985 - "Recent reports have suggested the use of dapsone for brown spider bites. "
05/01/2002 - "This progressive necrosis is analogous to that seen with brown recluse spider bites, where dapsone is an established mode of therapy, minimizing the area of tissue loss by a proposed antiinflammatory mechanism. "
11/01/2000 - "Dapsone should be used only in adult patients who experience necrotic arachnidism and who have been screened for glucose-6-phosphate dehydrogenase deficiency. "

06/01/2014 - "Verified spider bites in Oregon (USA) with the intent to assess hobo spider venom toxicity."
03/01/2012 - "Although wolf spider venom has been implicated in necrotic arachnidism without acceptably documented verification, limited, prospectively collected data demonstrate a lack of cutaneous necrosis. "
01/01/2013 - "Sphingomyelinases D (SMases D) or dermonecrotic toxins are well characterized in Loxosceles spider venoms and have been described in some strains of pathogenic microorganisms, such as Corynebacterium sp. After spider bites, the SMase D molecules cause skin necrosis and occasional severe systemic manifestations, such as acute renal failure. "
12/01/1999 - "The authors used a rabbit model of dermonecrotic arachnidism to address the therapeutic efficacy of intradermal (id) polyclonal anti-Loxosceles Fab fragments (alphaLoxd Fab) raised against Loxosceles deserta spider venom. "
06/01/1999 - "Loxosceles spider venom induces the production of alpha and beta chemokines: implications for the pathogenesis of dermonecrotic arachnidism."

05/01/2005 - "To compare the efficacy of dapsone, diphenhydramine, colchicine, and intralesional triamcinolone in the treatment of brown spider bites. "

12/01/1999 - "Intradermal anti-loxosceles Fab fragments attenuate dermonecrotic arachnidism."
12/01/1999 - "The authors used a rabbit model of dermonecrotic arachnidism to address the therapeutic efficacy of intradermal (id) polyclonal anti-Loxosceles Fab fragments (alphaLoxd Fab) raised against Loxosceles deserta spider venom. "

05/01/2005 - "To compare the efficacy of dapsone, diphenhydramine, colchicine, and intralesional triamcinolone in the treatment of brown spider bites. "

05/01/2005 - "To compare the efficacy of dapsone, diphenhydramine, colchicine, and intralesional triamcinolone in the treatment of brown spider bites. "

03/01/2011 - "Misdiagnosis of spider bites: bacterial associates, mechanical pathogen transfer, and hemolytic potential of venom from the hobo spider, Tegenaria agrestis (Araneae: Agelenidae)."
04/01/2008 - "This spider bites its prey by using a pairs of chelicerae, and injecting venom into the fly. "
02/01/2004 - "Mouse spider bites are unlikely to cause major envenoming but the clinical effects are consistent with neurotoxic venom and are more severe than the trapdoor spiders."
05/01/2002 - "The latter quantity was selected because this is the observed maximum amount of venom we detect when inoculating dermis with amounts likely to be deposited by a spider bite. "
09/01/1999 - "Specific treatment for spider bites is provided by the polyvalent anti-arachnidic antiserum produced by Butantan Institute, São Paulo, Brazil by immunizing horses with mixtures of venoms from Tityus serrulatus and T. "

08/01/2014 - "The finding of platelet antibodies after a Loxosceles spider bite has not been previously reported."
04/18/2000 - "Factor VIII antibodies developing after a spider bite."
01/01/1993 - "To study the effects of loxosceles laeta venom on red blood cells and the possible factors involved in hemolysis during arachnidism, in vitro models were designed to measure the role of loxosceles venom, calcium, complement and antibodies in the mechanism of red blood cell destruction. "

12/01/2004 - "The biology and epidemiology of the brown spider, the histopathology of envenomation and the immunogenicity of Loxosceles venom are reviewed, as are the clinical features, diagnosis and therapy of brown spider bites. "
09/01/2000 - "Detection of Loxosceles venom in lesional hair shafts and skin: application of a specific immunoassay to identify dermonecrotic arachnidism."
01/01/1993 - "To study the effects of loxosceles laeta venom on red blood cells and the possible factors involved in hemolysis during arachnidism, in vitro models were designed to measure the role of loxosceles venom, calcium, complement and antibodies in the mechanism of red blood cell destruction. "

01/01/2013 - "Brown Recluse spider bite mediated hemolysis: clinical features, a possible role for complement inhibitor therapy, and reduced RBC surface glycophorin A as a potential biomarker of venom exposure."
01/01/1993 - "To study the effects of loxosceles laeta venom on red blood cells and the possible factors involved in hemolysis during arachnidism, in vitro models were designed to measure the role of loxosceles venom, calcium, complement and antibodies in the mechanism of red blood cell destruction. "

12/01/2014 - "In a multicenter randomized placebo-controlled trial of redback spider antivenom for latrodectism, 224 patients (>7 years) with a redback spider bite and severe pain, with or without systemic effects, were randomized to receive normal saline solution (placebo) or antivenom after receiving standardized analgesia. "

01/01/2012 - "CASE REPORT Management of Periauricular and Auricular Necrotizing Wound From Brown Recluse Spider Bite Using Negative Pressure Wound Therapy and Wound Interface Modulation."
03/01/2007 - "Although not much is known regarding the application of negative pressure wound therapy (NPWT) to spider bites, this therapy has considerable literature support for its efficacy, cost-effectiveness and ease of use in chronic, difficult-to-heal wounds. "

07/01/1994 - "Local factors leading to infection were identified in nine of the cases and included motor vehicle accident-related and other trauma, surgery, a spider bite, and an intravenous infusion catheter. "

02/01/1977 - "A patient who had had an augmentation mammaplasty two years previously sustained a spider bite on one breast. "

11/01/1985 - "Treatment of spider bites with silver-impregnated porcine xenografts."