Anuria

Absence of urine formation. It is usually associated with complete bilateral ureteral (URETER) obstruction, complete lower urinary tract obstruction, or unilateral ureteral obstruction when a solitary kidney is present.

Also Known As:

Networked: 981 relevant articles (33 outcomes, 31 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Oliguria
2.	Calculi (Calculus)
3.	Acute Kidney Injury (Acute Renal Failure)
4.	Renal Insufficiency (Renal Failure)
5.	Exsanguination

Experts

1.	Gribouval, Olivier: 6 articles (02/2014 - 09/2005)
2.	Gubler, Marie-Claire: 5 articles (02/2014 - 04/2008)
3.	Antignac, Corinne: 4 articles (02/2014 - 09/2005)
4.	Corvol, Pierre: 4 articles (02/2014 - 04/2008)
5.	Michaud, Annie: 4 articles (02/2014 - 04/2008)
6.	Johnson, David W: 4 articles (12/2012 - 05/2003)
7.	Li, Philip Kam-Tao: 3 articles (03/2015 - 07/2003)
8.	Cui, Zhao: 3 articles (04/2014 - 01/2005)
9.	Zhang, Li: 3 articles (01/2014 - 04/2012)
10.	Brown, Fiona G: 3 articles (12/2012 - 01/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Anuria:

1.	CreatinineIBA 09/01/2013 - "The patient presented with oligo-anuria and a serum creatinine (Scr) of 9 mg/dL that improved back to baseline of 2 mg/dL after the successful procedure. " 01/01/2012 - "The patient's own convective clearance was substantial enough to maintain a modest creatinine clearance of 15 ml/min during sustained anuria. " 04/01/2002 - "To study the values of the renal resistive index (RI) before and at different points after relief of obstructive anuria and to correlate these values with the corresponding values of serum creatinine and with the recovery of renal function after release of obstruction. " 01/01/2015 - "AKI was defined as oligo-anuria (daily urine output <0.5 ml/kg/h) and/or an increase in serum creatinine (≥0.3 mg/dl from admission value within 48 hours or a 1.5 time from baseline level). " 07/01/2012 - "The former's serum creatinine returned to normal despite 3 months of anuria and the latter became dialysis-independent despite 2 months of progressive decline in renal function. "
2.	Anti-Bacterial Agents (Antibiotics)IBA 09/23/1969 - "[Effect of anuria and hemodialysis on the behavior of antibiotics]." 08/01/1997 - "Renal failure due to postrenal anuria resolved completely after intravenous antibiotics." 05/01/1986 - "Uterine evacuation, antibiotics, and vasopressor therapy were unsuccessful in reversing hypotension, coagulopathy, and anuria. " 09/01/2000 - "Multivariate analysis disclosed the following significant features separating the permanent from the reversible renal insufficiency group: patients in the first group had more tubular atrophy in their histology, more chronic use of mixed analgesics and/or NSAIDs, less oliguria or anuria as an acute symptom, fewer antibiotics as causative agents, more interstitial granuloma, more pronounced interstitial cell infiltration in their histology, and more imaging of renal shrinkage. " 02/01/1995 - "The authors recommend (1) that all patients with bloody diarrhea undergo microbiological evaluation for E coli O157:H7 before any surgical intervention; (2) avoidance of antibiotics and antimotility agents in patients with proven or suspected infection with E coli O157:H7 until the safety and efficacy of such interventions have been established in controlled trials; (3) that patients with E coli O157:H7 infections be evaluated for microangiopathic changes consistent with HUS in the week after onset of diarrhea; (4) nasogastric suction for severe symptoms, and frequent abdominal evaluations, tests (electrolytes/amylase), and roentgenograms to exclude treatable abdominal disorders; and (5) institution of hemodialysis for oliguria/anuria, acidosis, or rising creatinine. "
3.	Heparin (Liquaemin)FDA LinkGeneric 07/01/1969 - "[A case of anuria successfully treated with heparin during an acute pancreatitis. " 06/01/1993 - "Favorable outcome under simple heparin therapy of recurrent anuria due to graft renal vein thrombosis and subcapsular hematoma." 09/21/1974 - "We describe four cases treated by dialysis, corticosteroids, and heparin in anticoagulant doses in which there was remarkable improvement in renal function after prolonged anuria. " 01/01/1983 - "The patient was treated with steroid 'pulse', antiplatelet agents and heparin and a partial recovery of renal function was observed after 2 months of anuria. " 08/01/1977 - "She was treated with heparin, dipyridamole and hemodialysis; and after more than three months, her urinary output rose above 500 ml; and six months after the onset of anuria, dialysis treatment was stopped. "
4.	Urea (Carbamide)FDA LinkGeneric 06/01/1997 - "Onset of ARF; day on which oliguria or anuria detected, or serum urea first exceeded 10 mmol/L. " 06/01/1990 - "A three month old male calf showed the symptoms of anuria with ascites and high blood levels of urea. " 07/01/1976 - "These patients had unfavourable prognostic features during life, such as prolonged oliguria and anuria, absence of a diruetic phase, persistent elevations in BUN and persistently low urea excretion. " 03/01/2000 - "Regression analysis was used to estimate the mortality and TF rate ratios (RR) for peritoneal Kt/V urea (pKt/V) and pCCr, adjusting for age, gender, diabetes, months of follow-up prior to anuria, albumin, transport status, coronary artery disease, cardiovascular disease, and peripheral vascular disease. " 01/01/1993 - "DEG produced metabolic acidosis, which was completely balanced after doses of 1 and 5 ml/kg, but doses greater than 10 ml/kg produced non-compensated metabolic acidosis, hydropic degeneration of the tubuli, oliguria, anuria, accumulation of urea-N, and death in uraemic coma."
5.	ElectrolytesIBA 09/08/1957 - "[Reaction of blood electrolytes in experimental anuria]." 11/01/1957 - "[Acute anuric nephritis: reversal of cell permeability to electrolytes & corticosteroid overload; application to the control & therapy of anuria]." 03/06/1957 - "[Research on acute anuric nephritis; inversion of cellular permeability to electrolytes and corticoid overload; application to the control and treatment of anurias]." 05/01/1997 - "Acute renal insufficiency is a severe, but most frequent reversible illness followed by sudden onset, oliguria or anuria of indefinite duration, by rapid increase in decomposition products of protein catabolism in serum, by acidosis and fluid balance and electrolytes disorder. " 02/01/1995 - "The authors recommend (1) that all patients with bloody diarrhea undergo microbiological evaluation for E coli O157:H7 before any surgical intervention; (2) avoidance of antibiotics and antimotility agents in patients with proven or suspected infection with E coli O157:H7 until the safety and efficacy of such interventions have been established in controlled trials; (3) that patients with E coli O157:H7 infections be evaluated for microangiopathic changes consistent with HUS in the week after onset of diarrhea; (4) nasogastric suction for severe symptoms, and frequent abdominal evaluations, tests (electrolytes/amylase), and roentgenograms to exclude treatable abdominal disorders; and (5) institution of hemodialysis for oliguria/anuria, acidosis, or rising creatinine. "
6.	Ramipril (Altace)FDA LinkGeneric 07/15/2003 - "Of the 25 patients who still did not have complete anuria at 12 months, those assigned to ramipril had a better prognosis than did those assigned to no treatment (adjusted hazard ratio, 0.58 [CI, 0.36 to 0.94]). " 07/15/2003 - "With intention-to-treat multivariable analysis using the Cox model, it was estimated that at 3, 6, and 9 months, patients assigned to ramipril had a higher adjusted hazard of complete anuria than did patients assigned to no treatment. " 07/15/2003 - "At 12 months, 14 patients in the ramipril group and 22 in the control group developed anuria. " 01/01/2014 - "One study showed that compared with other antihypertensive drugs, long-term use (12 months) of the ACEi ramipril showed a significant reduction in the decline of residual kidney function in patients on CAPD (MD -0.93 mL/min/1.73m², 95% CI -0.75 to -0.11), and delayed the progression to complete anuria (RR 0.64, 95% CI 0.41 to 0.99). "
7.	Antihypertensive Agents (Antihypertensives)IBA 09/01/1976 - "A 29-year-old black woman with malignant hypertension and anuria was treated with hemodialysis and antihypertensive drugs. " 01/01/2014 - "One study showed that compared with other antihypertensive drugs, long-term use (12 months) of the ACEi ramipril showed a significant reduction in the decline of residual kidney function in patients on CAPD (MD -0.93 mL/min/1.73m², 95% CI -0.75 to -0.11), and delayed the progression to complete anuria (RR 0.64, 95% CI 0.41 to 0.99). "
8.	AmylasesFDA Link 02/01/1995 - "The authors recommend (1) that all patients with bloody diarrhea undergo microbiological evaluation for E coli O157:H7 before any surgical intervention; (2) avoidance of antibiotics and antimotility agents in patients with proven or suspected infection with E coli O157:H7 until the safety and efficacy of such interventions have been established in controlled trials; (3) that patients with E coli O157:H7 infections be evaluated for microangiopathic changes consistent with HUS in the week after onset of diarrhea; (4) nasogastric suction for severe symptoms, and frequent abdominal evaluations, tests (electrolytes/amylase), and roentgenograms to exclude treatable abdominal disorders; and (5) institution of hemodialysis for oliguria/anuria, acidosis, or rising creatinine. "
9.	imipenem drug combination cilastatin (Primaxin)FDA Link 01/01/1997 - "The recommended regimen in patients with anuria who receive CVVHD in this setting was estimated as intravenous imipenem-cilastatin, 500/500 mg, every 12 hrs." 01/01/1997 - "The objective of this study is to study the pharmacokinetics of imipenem-cilastatin in patients with anuria related to multiorgan failure during continuous venovenous hemodialysis (CVVHD) at a fixed blood flow rate of 60 ml/min, fixed dialysate flow rate of 20 ml/min, and drainage flow rate of 1-3 mil/min. A prospective open label study was designed in an intensive care unit in a university hospital. " 01/01/1997 - "Total body clearance of imipenem was 89.4 +/- 17.5 ml/min, including the clearance by CVVHD of 18.7 +/- 1.2 ml/min, and corresponding values for cilastatin were 31.7 +/- 9.0 ml/min and 13.7 +/- 3.4 ml/min. In conclusion, in patients with anuria, the elimination of imipenem-cilastatin was constant during CVVHD. "
10.	Uric Acid (Urate)IBA 01/01/2003 - "We report on 3 infants with obstructive anuria due to bilateral uric acid stones. " 01/01/2003 - "Dissolution of uric acid stones causing acute obstructing anuria in three consecutive infants." 06/01/1964 - "ANURIA DUE TO URIC ACID CRYSTALLURIA: AN UNUSUAL COMPLICATION OF THERAPY IN THE RETICULOSES." 09/23/1989 - "One patient had bilateral urate calculus with anuria; the other had recurrent staghorn calculus. " 10/01/1988 - "We hypothesize that oligo-anuria in this syndrome may be due to the previously recognized hyperuricemia causing a urate nephropathy superimposed on the glomerulopathy thus explaining its possible amenability to fluid and diuretic therapy."

Therapies and Procedures

1.	Artificial Kidney 12/01/1955 - "[Grave case of postoperative and post-transfusion anuria cured by use of artificial kidney]." 11/01/1955 - "[A severe case of postoperative and post-transfusional anuria cured after an application of artificial kidneys]." 11/01/1955 - "[Presentation of a grave case of postoperative and post-transfusional anuria cured by use of the artificial kidney]." 11/01/1962 - "[Therapy of anuria using the artificial kidney]." 11/01/1960 - "[Post-traumatic anuria for 27 days, necessitating prolonged respiratory assistance and 6 epurations with the artificial kidney. "
2.	Lithotripsy (Extracorporeal Shockwave Lithotripsy) 07/01/1995 - "Of 500 extracorporeal lithotripsies performed by the authors anuria arose in 2 cases on postlithotripsy days 3 and 5. There was also systemic intoxication of unclear origin." 07/01/1995 - "[Anuria following extracorporeal lithotripsy]." 01/01/2008 - "A holmium laser is a safe and effective modality of ureteroscopic lithotripsy in patients with significant renal impairment or even obstructive anuria. " 03/01/2014 - "Management of calculus anuria using ureteroscopic lithotripsy as a first line treatment: its efficacy and safety." 09/01/2011 - "Ureteroscopy and holmium laser lithotripsy represent an effective and safe modality for the treatment of anuria caused by ureteral calculi."
3.	Peritoneal Dialysis 10/01/2011 - "Persisting anuria was confirmed postnatally and peritoneal dialysis started on the second day of life. " 12/01/2008 - "1,432 peritoneal dialysis patients with anuria from January 1, 1994, to January 31, 2005, in a national sample (1,428 with Kt/V, 1,416 with Ccr). " 06/01/2008 - "Peritoneal dialysis prescription suitable for children with anuria." 09/01/2007 - "We report on a female patient who presented with anuria in the neonatal period, requiring peritoneal dialysis until 5 months of age with unexpected diuresis recovery at 2 months of age. " 05/01/2005 - "Their survival was analyzed according to their baseline peritoneal Kt/V at the time of documentation of anuria and at the time of their latest altered peritoneal dialysis (PD) prescription (subsequent Kt/V). "
4.	Continuous Ambulatory Peritoneal Dialysis (CAPD) 03/01/2015 - "This study was conducted to compare the impact of "initial anuria" and rapid RRFD on the long-term prognosis of CAPD patients. " 03/01/2015 - "For the "anuria" group, anuria was detected from CAPD initiation and persisted for > 6 months (n = 27). " 03/01/2015 - "According to the timing of anuria and the slope of RRFD, a total of 255 incident CAPD patients were divided into 3 groups. " 03/01/2015 - "Comparison of the impact of "fast decline" in residual renal function and "initial anuria" on long-term outcomes in CAPD patients." 01/01/2014 - "Multivariate analysis provided a significant discriminatory influence pertaining to age >50 years, CRP>0.6 mg/dl, male gender, diabetes, LVH, CAPD and anuria, when comparing group 1 and group 2. Risk factors most related to the development of CV disease in PD in Portugal are age >50 years, CRP>0.6 mg/dL, male gender, diabetes, LVH, CAPD and anuria."
5.	Solid-State Lasers 01/01/2008 - "In this study, we try to evaluate the efficacy and safety of holmium lasers for treatment of ureteric stones in patients with renal impairment or obstructive anuria. " 09/01/2011 - "Management of calcular anuria in adults caused by ureteric stones: By using of ureteroscopy and holmium laser." 01/01/2008 - "A holmium laser is a safe and effective modality of ureteroscopic lithotripsy in patients with significant renal impairment or even obstructive anuria. " 09/01/2011 - "To present our clinical outcomes in the management of anuria in adult patients caused by ureteral calculi by using of ureteroscopy and holmium laser. " 09/01/2011 - "Ureteroscopy and holmium laser lithotripsy represent an effective and safe modality for the treatment of anuria caused by ureteral calculi."