Antivenins (Antivenoms)

02/01/2012 - "This study elucidated the active compounds, accounting for the antivenin activity of traditionally used herbs and suggested the most suitable formulation, which may help to develop potent medicines for the treatment of snake bite in the future."
11/01/1998 - "A large-scale clinical trials was conducted, according to World Health Organization Good Clinical Practice guidelines, in 7 centres in north Cameroon to determine the safety and efficacy of a polyvalent antivenom composed of purified F(ab')2. This study included 223 patients presenting clinically with obvious snake bite, predominantly due to Echis ocellatus (viper), the most abundant species in this savannah region. "
08/01/2022 - "Snakebite envenomation is responsible for over 100,000 deaths and 400,000 cases of disability annually, most of which are preventable through access to safe and effective antivenoms. "
03/01/2022 - "Antivenom has been used successfully to treat systemic and progressive, local manifestations of envenomations inflicted by Echis coloratus, the second most common cause of snake envenomation in Israel. "
10/30/2020 - "Antivenoms are currently the most effective medication used in the treatment of snakebites. "

12/01/2020 - "Searching for more effective and safe antivenom is mandatory for viper bites treatment. "
09/01/2002 - "Despite considerable evidence regarding the safety and efficacy of antivenin in the treatment of rattlesnake bites in adults, controversy persists regarding the roles of antivenin and surgery in the treatment of rattlesnake envenomations in children. "
11/19/2023 - "The usual antivenom dose for effective treatment of a Boomslang bite is two 10 ml vials. "
04/01/2022 - "To describe the South Australian paediatric redback spider bite experience and to examine the hypothesis that redback antivenom (RBAV) treatment in children is clinically effective. "
01/01/2022 - "However, in China, there are only four types of terrestrial snake antivenoms, none of which are effective in the treatment of sea snake bites. "

01/01/1998 - "The advance in supportive care and antivenom efficacy has markedly improved the outcome of patients with scorpion envenomation."
05/14/2009 - "In a randomized, double-blind study, the efficacy of scorpion-specific F(ab')(2) antivenom, as compared with placebo, was assessed in 15 children 6 months to 18 years of age who were admitted to a pediatric intensive care unit with clinically significant signs of scorpion envenomation. "
04/01/2016 - "Nowadays, antivenom derived from hyper immune horses is the only effective treatment for sever scorpion stings. "
09/01/2016 - "These scFvs are potential candidates to be part of a novel recombinant antivenom of human origin that could confer protection against scorpion stings. "
01/01/2018 - "Efficacy of Scorpion Antivenom in Grade III and IV Scorpion Envenomation."

11/01/2016 - "Antivenom is most effective when administered early because this will halt the progression of edema and may reverse the systemic effects of envenomation. "
03/01/1999 - "Antivenom was fully effective in the neutralization of lethal, hemorrhagic, edema-forming, myotoxic and indirect hemolytic effects of B. "
03/01/1999 - "atrox, the antivenom completely neutralized the lethal, hemorrhagic, myotoxic and indirect hemolytic effects, and was partially effective in neutralizing edema-forming activity. "
06/02/2023 - "These results were confirmed by a histological study, which showed that monospecific antivenoms neutralized severe signs of mortality, such as congestion of blood vessels in the heart and kidneys, pulmonary and renal edema, cytoplasmic vacuolization of hepatocytes in the liver, and infiltration of inflammatory cells in the brain and spleen. "
10/01/2022 - "MLV was recognized by anti-elapid serum, but this antivenom did not neutralize edema formation. "

07/01/2017 - "The most useful treatment for spider bite is anti-venom administration. "
03/01/2005 - "Antivenom is scarce; capture of the offending spider appears to be most helpful in the diagnosis and proper treatment of spider bites."
01/01/2016 - "A better knowledge of the burden and risk factors associated with severity due to spider bites would lead to improved management with a reduction of sequelae usually seen for this neglected health problem, and would ensure proper use of antivenoms in remote localities in the Brazilian Amazon. "
01/01/2019 - "The Efficacy of Antivenin Latrodectus (Black Widow) Equine Immune F(ab')2 Versus Placebo in the Treatment of Latrodectism: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial."
08/01/2006 - "The efficacy of antivenom in loxoscelism treatment."