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Tricyclic Antidepressive Agents (Tricyclic Antidepressants)

Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
Also Known As:
Tricyclic Antidepressants; Antidepressive Agents, Tricyclic; Antidepressant Drugs, Tricyclic; Agent, Tricyclic Antidepressive; Agents, Tricyclic Antidepressive; Antidepressant Drug, Tricyclic; Antidepressant, Tricyclic; Antidepressive Agent, Tricyclic; Drug, Tricyclic Antidepressant; Drugs, Tricyclic Antidepressant; Tricyclic Antidepressant Drugs; Antidepressants, Tricyclic; Tricyclic Antidepressant; Tricyclic Antidepressant Drug; Tricyclic Antidepressive Agent
Networked: 2843 relevant articles (327 outcomes, 294 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Barrot, Michel: 8 articles (12/2021 - 03/2008)
2. Yalcin, Ipek: 8 articles (12/2021 - 03/2008)
3. Jensen, Troels S: 8 articles (01/2021 - 04/2001)
4. Wiffen, Philip J: 7 articles (05/2019 - 12/2012)
5. Attal, N: 6 articles (09/2021 - 11/2006)
6. Derry, Sheena: 6 articles (05/2019 - 12/2012)
7. Moore, R Andrew: 6 articles (05/2019 - 12/2012)
8. Dworkin, Robert H: 6 articles (02/2015 - 11/2003)
9. Berger, Ariel: 6 articles (03/2012 - 04/2004)
10. Oster, Gerry: 6 articles (03/2012 - 04/2004)

Related Diseases

1. Pain (Aches)
2. Neuralgia (Stump Neuralgia)
3. Panic Disorder (Panic Attack)
4. Depressive Disorder (Melancholia)
5. Anxiety Disorders (Anxiety Disorder)

Related Drugs and Biologics

1. Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)
2. Antidepressive Agents (Antidepressants)
3. Amitriptyline (Elavil)
4. Serotonin (5 Hydroxytryptamine)
5. Anticonvulsants (Antiepileptic Drugs)
6. Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)
7. Gabapentin (Neurontin)
8. Norepinephrine (Noradrenaline)
9. Imipramine (Janimine)
10. Opioid Analgesics (Opioids)

Related Therapies and Procedures

1. Therapeutics
2. Analgesia
3. Drug Therapy (Chemotherapy)
4. Transcutaneous Electric Nerve Stimulation (TENS)
5. Physical Therapy Modalities (Physical Therapy Technique)