Antibodies

Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).

Networked: 92632 relevant articles (2923 outcomes, 8217 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Vincent, Angela: 152 articles (12/2015 - 01/2002)
2.	Shoenfeld, Yehuda: 108 articles (06/2015 - 01/2002)
3.	Dalmau, Josep: 90 articles (01/2016 - 07/2002)
4.	Shoenfeld, Y: 70 articles (02/2015 - 01/2000)
5.	Graus, Francesc: 61 articles (01/2016 - 03/2003)
6.	Gershwin, M Eric: 58 articles (06/2015 - 02/2002)
7.	Hashimoto, Takashi: 57 articles (11/2015 - 11/2002)
8.	Vincent, A: 51 articles (08/2015 - 04/2000)
9.	Yuki, Nobuhiro: 51 articles (06/2015 - 03/2002)
10.	Marsh, Kevin: 46 articles (01/2016 - 02/2002)

Related Diseases

1.	Infection 01/01/2008 - "Immunogenicity evaluations in human papillomavirus (HPV) vaccine trials have relied on serological samples, yet cervical antibodies are likely to be most relevant for protection against infection. " 03/23/2013 - "The protease is highly immunogenic and antibodies against AsaP1 evoke a passive protection against infection with A. " 01/01/2013 - "Because pre-existing AIV antibodies can infer some protection against highly pathogenic AIV (HPAI H5N1), our results imply that some wild waterfowl in Alaska could be protected from lethal HPAIV infections. " 01/01/2013 - "Furthermore, captive chimpanzees are highly susceptible to human pathogens, and their induced antibodies reveal not only their history of infection, but also the possibility of protection against human pathogens." 10/18/2012 - "HIV-1-specific antibodies and CD8(+) cytotoxic T cells are detected in most HIV-1-infected people, yet HIV-1 infection is not eradicated. "
2.	Neoplasms (Cancer) 07/01/2008 - "Importantly, most studies of EPO-R detection in tumor tissue have provided falsely positive results because of the lack of EPO-R specific antibodies. " 06/01/1991 - "2) In an animal model on tumor localization and biodistribution studies, CEA-specific antibodies obtained more highly tumor targeting and cleared more rapidly from the blood and non-tumor organs than CEA-nonspecific antibodies did, so that tumor to nontumor ratios was increased. " 12/01/2015 - "The patient's disease remained in remission 2 years after the diagnosis with a remarkable reduction of tumor burden and a persisting high titer of anti-Hu antibodies. " 03/01/2013 - "Combination of antibodies with irradiation was most effective in reducing cell survival and tumor growth. " 12/01/2012 - "Blockade of Olfml3 by anti-Olfml3 antibodies is highly effective in reducing tumor vascularization, pericyte coverage, and tumor growth. "
3.	Malaria 12/01/2014 - "Mouse model studies have highlighted the essential role that CD8(+) T cells play in protection against preerythrocytic stages of malaria; however, there is mounting evidence that antibodies are also important in these stages. " 10/15/2015 - "Findings suggest that naturally acquired binding-inhibitory antibodies are an important functional mechanism that contributes to protection against malaria and further supports the potential of EBA-175 as a vaccine candidate. " 02/01/2010 - "Baculovirus-based nasal drop vaccine confers complete protection against malaria by natural boosting of vaccine-induced antibodies in mice." 11/01/2015 - "In multivariate analysis, in utero malaria exposure was associated with a significant reduction in the transfer of anti-VCA-p18 and anti-EBNA1 antibodies to the neonates (P = 0.0234 and P = 0.0017, respectively). " 01/01/2015 - "Constant exposure to the pathogen leads to the acquisition of antibodies and high levels of antibodies have been associated with clinical protection against malaria. "
4.	Human Influenza (Influenza) 01/01/2015 - "Although antibodies are an important defense mechanism providing sterilizing immunity, in older adults, the cellular immune response is also needed for clinical protection against the serious complications of influenza. " 01/01/2012 - "In contrast, the elderly had high vaccine uptake and low attack rate but low levels of protective antibodies, underlining that factors other than HI antibodies are involved in protection against influenza A(H1N1)pdm09. " 04/10/2009 - "High-affinity antibodies against a conserved epitope could provide immunity to the diverse influenza subtypes and protection against future pandemic viruses. " 10/01/2014 - "Though both preexisting HAI and CDL antibodies were associated with protection against clinical influenza, our data suggested that CDL was not a better correlate than HAI. " 05/01/2012 - "Our results show that, after one dose of an H5N1 LAIV, pulmonary influenza-specific lymphocytes are the main contributors to clearance of challenge virus from the lungs and that contributions of influenza-specific enzyme-linked immunosorbent assay (ELISA) antibodies in serum and splenic CD8(+) T cells were negligible. "
5.	Lymphoma (Lymphomas) 03/01/1980 - "Inhibitory antibodies could be removed by absorption with C3 H B lymphoma cells and upon elution from antibody-coated cells proved again highly effective in inhibiting CML. " 02/01/1983 - "Immunohistochemical approach with the antibodies was very helpful for diagnosis of malignant lymphomas. " 05/15/1996 - "The BCL1 lymphoma in Balb/c mice can be successfully treated with bispecific (anti-CD3 x anti-idiotype) antibodies (BSABs). " 04/01/2008 - "TetraMcAbs, with a molecular mass only 25 kDa higher than native divalent antibodies (DiMcAb), were shown not only to be as effective in mediating CDC and antibody-dependent cellular cytotoxicity against B-lymphoma cells as DiMcAbs but also to have antiproliferative and apoptosis-inducing activity markedly superior to that of DiMcAbs. " 12/01/1987 - "Therefore, when these antibodies are used to determine the immunophenotype of malignant lymphomas, the B-cell nature can be predicted with great confidence only when two, preferably three or more, of the antibodies give positive results. "

Related Drugs and Biologics

1.	Immunoglobulin G (IgG)
2.	Antigens
3.	Immunoglobulin M (IgM)
4.	Immunoglobulin A (IgA)
5.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
6.	Vaccines
7.	Immunoglobulin E (IgE)
8.	Proteins (Proteins, Gene)
9.	Immunoglobulins (Immunoglobulin)
10.	Monoclonal Antibodies

Related Therapies and Procedures

1.	Immunotherapy
2.	Drug Therapy (Chemotherapy)
3.	Heterologous Transplantation (Xenotransplantation)
4.	Radioimmunotherapy
5.	Transplants (Transplant)